Relationship between Circulating Serpina3g, Matrix Metalloproteinase-9, and Tissue Inhibitor of Metalloproteinase-1 and -2 with Chronic Obstructive Pulmonary Disease Severity [PDF]
Biomolecules, 2019 Chronic obstructive pulmonary disease (COPD) is influenced by genetic and environmental factors. A protease-antiprotease imbalance has been suggested as a possible pathogenic mechanism for COPD.
Pelin Uysal, Hafize Uzun
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Prognostic Significance of Tissue Inhibitor of Metalloproteinase-1 in Breast Cancer [PDF]
International Journal of Breast Cancer, 2012 Introduction. Despite advances in breast cancer systemic treatment, new prognostic and predictive factors are still needed. Tissue inhibitor of metalloproteinase-1 (TIMP-1), a physiologic inhibitor of matrix metalloproteinases (MMPs), can act in both pro-
Arunee Dechaphunkul +6 more
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Tissue Inhibitor of Metalloproteinase-1 Is Increased in Chagasic Cardiomyopathy. [PDF]
Am J Trop Med Hyg, 2021 ABSTRACT. Chagas disease (CD) mainly conveys stroke risk through structural cardiac disease. However, stroke and cognitive impairment are seen in CD independently of cardiac disease severity. Chronic inflammation may be an explanation for this association, because inflammation plays an important role in the pathogenesis of acute ischemic stroke and ...
Garcia KO +17 more
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Secretory autophagy promotes Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 [PDF]
Journal of Biomedical Science, 2022 Background Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1), an inflammatory cytokine, under serum-depleted conditions which leads to suppression of lung cancer cell metastasis has been reported.
Shan-Ying Wu +8 more
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Expression of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Endometriosis Menstrual Blood [PDF]
Diagnostics, 2020 Endometriosis is a gynecological disease characterized by the presence of endometrial-like tissue outside the uterine cavity. Remodeling of the extracellular matrix (ECM) is a prerequisite for tissue implantation. The presence of matrix metalloproteinase
Tita Husnitawati Madjid +3 more
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Roles of Tissue Inhibitor of Metalloproteinase-1 in Severe Asthma. [PDF]
Allergy Asthma Immunol Res, 2023 Kim SH.
europepmc +3 more sources
Bioengineering, 2022 Hypertension (HTN) is a leading risk factor for cardiovascular (CV) disease. Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are thought to be actively involved in the remodeling of the CV extracellular matrix (ECM) during ...
Krasimir Kostov, Alexander Blazhev
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Tissue inhibitor matrix metalloproteinase 1 and risk of type 2 diabetes in a Chinese population [PDF]
BMJ Open Diabetes Research & Care, 2020 IntroductionThe non-invasive enhanced liver fibrosis (ELF) score—comprising tissue inhibitor of matrix metalloproteinases-1 (TIMP1), hyaluronic acid (HA) and amino-terminal propeptide of type III procollagen (PIIINP)—has been shown to accurately predict ...
Yeli Wang
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Tissue inhibitor of metalloproteinase-1 and interleukin-10 in serum from naïve and scrapie infected sheep [PDF]
Veterinary and Animal Science, 2019 Tissue inhibitor of metalloproteinase-1 (TIMP-1) and interleukin-10 (IL-10) were identified as potential biomarkers for ovine scrapie in a mouse model.
Marta G. Silva +4 more
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Saudi Dental Journal, 2014 Background: Matrix metalloproteinase-1 (MMP-1) is a member of a family of enzymes that can degrade most extracellular matrix macromolecules. Extracellularly, MMPs are controlled by tissue inhibitors of metalloproteinases (TIMPs) and by mechanisms of pro ...
Pallavi S. Ghodpage +3 more
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