Upregulation of matrix metalloproteinase 9 (MMP9)/tissue inhibitor of metalloproteinase 1 (TIMP1) and MMP2/TIMP2 ratios may be involved in lipopolysaccharide-induced acute lung injury [PDF]
Journal of International Medical Research, 2020 Objective This study aimed to examine the changes and significance of matrix metalloproteinase 9 (MMP9), MMP2, tissue inhibitor of metalloproteinase 1 (TIMP1), and TIMP2 in rats with lipopolysaccharide (LPS)-induced acute lung injury (ALI).
Guobing Chen, Bizhen Zhu, Huixuan Shi
exaly +3 more sources
Inactivation of tissue inhibitor of metalloproteinase‐1 by peroxynitrite [PDF]
FEBS Letters, 1996 Peroxynitrate (ONOO−) has recently been implicated in connective tissue destruction in vivo. We have studied the effect of ONOO− on the activity of tissue inhibitor of metalloproteinase‐1 (TIMP‐1) in vitro. The inactivation of TIMP‐1 by ONOO− was dose dependent with 50 μM ONOO− reducing the inhibitory activity of TIMP‐1 towards gelatinase‐A by 50 ...
Frears, Emma R. +4 more
openaire +3 more sources
Tissue inhibitor of metalloproteinase-1 [PDF]
Springer Reference Medizin, 2018 S. Holdenrieder, P. Stieber
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Urinary matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 biomarkers for predicting renal scar in children with urinary tract infection [PDF]
Urology Research and Practice, 2019 Objective: Urinary tract infection occurs in 1.8–6.6% of children under 6 years old. The aim of this study was to assess the urinary concentrations of matrix metalloproteinase 9 (MMP9) and tissue inhibitor of metalloproteinase 1 (TIMP1), in children with
Seyed Mohammad Abedi +4 more
doaj +2 more sources
Tissue Inhibitor of Metalloproteinase 1 Measurement [PDF]
Definitions, 2020 openaire +2 more sources
Multifunctionality of tissue inhibitor of metalloproteinase-1 in central nervous system diseases
Brain Research BulletinCentral nervous system (CNS) diseases are characterized by high morbidity, long disease courses, and irreversible neurological impairment, often resulting from damage to the neurovascular unit (NVU).
Linke Zhong +6 more
doaj +3 more sources
Prognostic value of determination of matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 in follicular fluid in patients in vitro fertilization programs [PDF]
Гинекология, 2021 Aim. To determine the prognostic significance of matrix metalloproteinase-1 (MMP-1) and tissue metalloproteinase-1 inhibitor (TIMP-1) in the follicular fluid (FF) in patients with infertility to improve the effectiveness of in vitro fertilization (IVF ...
Olga A. Marinova +2 more
doaj +1 more source
Increased matrix metalloproteinase-9 to tissue inhibitor of metalloproteinase-1 ratio in smokers with airway hyperresponsiveness and accelerated lung function decline. [PDF]
Int J Chron Obstruct Pulmon Dis, 2018 Background Airway hyperresponsiveness (AHR) is associated with airway inflammation and a rapid decline in lung function and is a predictor of future risk of COPD among smokers.
Lo CY +8 more
europepmc +2 more sources
Journal of Advanced Biotechnology and Experimental Therapeutics, 2023 SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2 which is the causative agent of spreading coronavirus disease 2019 that is known as COVID-19 pandemic, the disease leads to severe acute respiratory illness. Matrix metalloproteinases-
May K. Ismael +2 more
doaj +1 more source
Tissue inhibitor of metalloproteinase-1 predicts adiposity in humans [PDF]
European Journal of Endocrinology, 2007 Objective: Tissue inhibitor of metalloproteinase (TIMP)-1 is upregulated in fat of obese rodents and promotes adipose tissue development in these animals. However, it is unclear whether TIMP-1 independently predicts adiposity in humans and whether serum levels are increased in s.c. and visceral obesity. Design: Twenty-four lean, 16 s.c.
Susan, Kralisch +6 more
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