Urinary matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 biomarkers for predicting renal scar in children with urinary tract infection [PDF]
Urology Research and Practice, 2019 Objective: Urinary tract infection occurs in 1.8–6.6% of children under 6 years old. The aim of this study was to assess the urinary concentrations of matrix metalloproteinase 9 (MMP9) and tissue inhibitor of metalloproteinase 1 (TIMP1), in children with
Seyed Mohammad Abedi +4 more
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Multifunctionality of tissue inhibitor of metalloproteinase-1 in central nervous system diseases
Brain Research BulletinCentral nervous system (CNS) diseases are characterized by high morbidity, long disease courses, and irreversible neurological impairment, often resulting from damage to the neurovascular unit (NVU).
Linke Zhong +6 more
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Upregulation of matrix metalloproteinase 9 (MMP9)/tissue inhibitor of metalloproteinase 1 (TIMP1) and MMP2/TIMP2 ratios may be involved in lipopolysaccharide-induced acute lung injury [PDF]
Journal of International Medical Research, 2020 Guobing Chen, Bizhen Zhu, Huixuan Shi
exaly +2 more sources
Prognostic value of determination of matrix metalloproteinase-1 and tissue inhibitor of matrix metalloproteinase-1 in follicular fluid in patients in vitro fertilization programs [PDF]
Гинекология, 2021 Aim. To determine the prognostic significance of matrix metalloproteinase-1 (MMP-1) and tissue metalloproteinase-1 inhibitor (TIMP-1) in the follicular fluid (FF) in patients with infertility to improve the effectiveness of in vitro fertilization (IVF ...
Olga A. Marinova +2 more
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Inactivation of tissue inhibitor of metalloproteinase‐1 by peroxynitrite [PDF]
FEBS Letters, 1996 Peroxynitrate (ONOO−) has recently been implicated in connective tissue destruction in vivo. We have studied the effect of ONOO− on the activity of tissue inhibitor of metalloproteinase‐1 (TIMP‐1) in vitro. The inactivation of TIMP‐1 by ONOO− was dose dependent with 50 μM ONOO− reducing the inhibitory activity of TIMP‐1 towards gelatinase‐A by 50 ...
Frears, Emma R. +4 more
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Journal of Advanced Biotechnology and Experimental Therapeutics, 2023 SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2 which is the causative agent of spreading coronavirus disease 2019 that is known as COVID-19 pandemic, the disease leads to severe acute respiratory illness. Matrix metalloproteinases-
May K. Ismael +2 more
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Tissue inhibitor of metalloproteinase-1 predicts adiposity in humans [PDF]
European Journal of Endocrinology, 2007 Objective: Tissue inhibitor of metalloproteinase (TIMP)-1 is upregulated in fat of obese rodents and promotes adipose tissue development in these animals. However, it is unclear whether TIMP-1 independently predicts adiposity in humans and whether serum levels are increased in s.c. and visceral obesity. Design: Twenty-four lean, 16 s.c.
Susan, Kralisch +6 more
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International journal of health sciences, 2022 Colorectal cancer is reported as the third most common case worldwide in men and accounts for 10% of all cancers. Matrix metalloproteinases (MMPs) comprise a family of zinc-dependent endopeptidases that affect the degradation and remodeling of extracellular components and contribute to the three Hallmarks of cancer.
I Gusti Agung Gede Darma Putra Suryapranata +2 more
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Patologìâ, 2023 Airway remodeling is a significant factor in the progression of respiratory failure in bronchial asthma (BA). Obesity can contribute to inflammation, and consequently – airway remodeling, by increased production of matrix proteinase (MMP).
V. V. Kachkovska, L. N. Prystupa
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Tissue Inhibitor of Metalloproteinase 1 Regulates Resistance to Infection [PDF]
Infection and Immunity, 2005 ABSTRACT Tissue inhibitor of metalloproteinase 1 (TIMP-1)-deficient mice are resistant to Pseudomonas aeruginosa corneal infections. Corneas healed completely in TIMP-1-deficient mice, and infections were cleared faster in TIMP-1-deficient mice than in wild-type littermates.
Marie Mei, Lee +7 more
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