Results 31 to 40 of about 95,143 (290)

Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease [PDF]

Korean Journal of Pediatrics, 2010
Purpose : Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary artery wall with diffuse vasculitis ...
Ki Wook Yun, Sin Weon Sin, Jung Ju Lee, Soo Ahn Chae, In Seok Lim, Eung Sang Choi, Byoung Hoon Yoo, Mi-Kyung Lee   +7 more
doaj   +1 more source

Replacement of Conserved Cysteines in Human Tissue Inhibitor of Metalloproteinases-1 [PDF]

Journal of Biological Chemistry, 1997
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is resistant to extremes of temperature and pH. This is thought to be due in part to the presence of six sulfhydryl bridges presumed to maintain the structural integrity of the molecule. As part of a study looking at structure-function relationships, a number of the conserved cysteine residues in TIMP-1
N C, Caterina, L J, Windsor, A E, Yermovsky, M K, Bodden, K B, Taylor, H, Birkedal-Hansen, J A, Engler   +6 more
openaire   +2 more sources

Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer

Tumor Biology, 2018
Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient’s prognosis is difficult to determine.
Alli Laitinen, Jaana Hagström, Harri Mustonen, Arto Kokkola, Taina Tervahartiala, Timo Sorsa, Camilla Böckelman, Caj Haglund   +7 more
doaj   +1 more source

Histopathologic Findings Associated With Matrix Metalloproteinases Proceeding to Recurrence of Primary Spontaneous Pneumothorax in Adolescents

Frontiers in Pediatrics, 2021
Background: Primary spontaneous pneumothorax is potentially life-threatening, and its recurrence is always a serious problem. Pathological examination provides molecular insights into the pathophysiology of primary spontaneous pneumothorax.Objectives: To
Chih-Yung Chiu, Jim-Ray Chen, Shun-Ying Yin, Chia-Jung Wang, Tzu-Ping Chen, Tsan-Yu Hsieh   +5 more
doaj   +1 more source

Expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in ulcerative colitis

World Journal of Gastroenterology, 2006
To examine the expression of metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in the colonic mucosa of patients with ulcerative colitis (UC).Reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry were used to study the expression of MMP-1 and TIMP-1 at both mRNA and protein levels in patients ...
Ying-De, Wang, Pei-Yun, Yan
openaire   +2 more sources

Relationships of MMP-9 and TIMP-1 proteins with chronic obstructive pulmonary disease risk: A systematic review and meta-analysis

Journal of Research in Medical Sciences, 2016
Background: We performed this meta-analysis in order to collect all the relevant studies to clarify the correlations of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) with chronic obstructive pulmonary disease ...
Yangxue Li, Yang Lu, Zhuo Zhao, Junnan Wang, Jianxin Li, Weiming Wang, Shumei Li, Lei Song   +7 more
doaj   +1 more source

Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer

World Journal of Gastroenterology, 2011
To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer.One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study. The serum concentrations of MMP-1 and TIMP-1 in these patients and in fifty healthy controls were determined ...
Yılmaz, Özkan, KISLI, Erol, Begenik, Hüseyin, ADAS, Mine, HASIRCI, Ismail, Kemik, Ahu Sarbay, Dulger, Ahmet Cumhur, TUZUN, Sefa, KOTAN, Cetin, Kemik, Özgür, SUMER, Aziz, PURISA, Sevim   +11 more
openaire   +4 more sources

Tissue Inhibitor of Metalloproteinases-1 Regulation by Aldosterone [PDF]

Hypertension, 2016
See related article, pp 1309–1320 Primary aldosteronism (PA), first characterized by Conn in 1955,1 results in hypertension secondary to the excessive production of aldosterone by the adrenal cortex—in many cases because of the presence of a benign aldosterone-producing adenoma.
Criselda, Mendoza-Milla, Michael P, Czubryt   +1 more
openaire   +2 more sources

IL-1β-Induced Matrix Metalloprotease-1 Promotes Mesenchymal Stem Cell Migration via PAR1 and G-Protein-Coupled Signaling Pathway

Stem Cells International, 2018
Mesenchymal stem cells (MSCs) are known for homing to sites of injury in response to signals of cellular damage. However, the mechanisms of how cytokines recruit stem cells to target tissue are still unclear.
Ming-Siou Chen, Cheng-Yu Lin, Yun-Hsuan Chiu, Chie-Pein Chen, Pei-Jiun Tsai, Hwai-Shi Wang   +5 more
doaj   +1 more source

Tissue inhibitor of metalloproteinases 1, a novel biomarker of tuberculosis

Molecular Medicine Reports, 2016
Tuberculosis (TB) is an important infectious disease of humans and other animals. Conventional diagnostic methods, including the tuberculin skin test, chest X‑rays and bacterial culture, have certain innate disadvantages for the early, rapid and specific diagnosis of tuberculosis.
Chen, Y., Wang, J., Ge, P., Cao, D., Miao, B., Robertson, I., Zhou, X., Zhang, L., Chen, H., Guo, A.   +9 more
openaire   +3 more sources