Results 31 to 40 of about 174,270,932 (291)

METRONIDAZOLE GEL EFFECT ON RATS WITH BACTERIA-INDUCED PERIODONTITIS

ODONTO: Dental Journal, 2020
Background: Periodontitis is an inflammatory disease in the periodontal tissue and causes progressive tissue damage. Tissue Inhibitor of Matrix Metalloproteinases-1 (TIMP-1) is directly responsible for the pathogenesis of periodontal diseases.
Muhamat Muhtar S. Abdurrohman, R. Rama Putranto   +1 more
doaj   +1 more source

Dependence of TIMP-1 plasma levels on preanalytical specimen handling [PDF]

, 2008
Background: Tissue inhibitor of metalloproteinases-1 (TIMP-1) in blood might be a helpful biomarker in various diseases. However, various authors report that TIMP-1 is dependent on preanalytical procedures.
Doss, Robert, Dorothea Nagel, Barry Dowell, Stieber, Petra, Marie Dresse, Dowell, Barry, Dresse, Marie, Robert Doss, Davis, Gerard, Ganser, Eva-Maria, Gerard Davis, Eva-Maria Ganser, Nagel, Dorothea, Petra Stieber   +13 more
core   +1 more source

Gender peculiarities and prognostic value of matrix metalloproteinase and their inhibitors system in patients with acute Q-wave left ventricle myocardial infarction

Zaporožskij Medicinskij Žurnal, 2015
Matrix metalloproteinases play a key role in postinfarction remodeling of the heart. The aim was to study gender and age peculiarities of matrix metalloproteinases and their inhibitors, and determine their prognostic value in post-infarction aneurysm ...
S. M. Kyselov
doaj   +1 more source

Clinical significance of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 and 2 in Kawasaki disease [PDF]

Korean Journal of Pediatrics, 2010
Purpose : Kawasaki disease (KD) is a systemic vasculitis, a leading cause of pediatric acquired heart disease. Histopathological findings of coronary artery lesion (CAL) in KD indicate destruction of the coronary artery wall with diffuse vasculitis ...
Ki Wook Yun, Sin Weon Sin, Jung Ju Lee, Soo Ahn Chae, In Seok Lim, Eung Sang Choi, Byoung Hoon Yoo, Mi-Kyung Lee   +7 more
doaj   +1 more source

Replacement of Conserved Cysteines in Human Tissue Inhibitor of Metalloproteinases-1 [PDF]

Journal of Biological Chemistry, 1997
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is resistant to extremes of temperature and pH. This is thought to be due in part to the presence of six sulfhydryl bridges presumed to maintain the structural integrity of the molecule. As part of a study looking at structure-function relationships, a number of the conserved cysteine residues in TIMP-1
N C, Caterina, L J, Windsor, A E, Yermovsky, M K, Bodden, K B, Taylor, H, Birkedal-Hansen, J A, Engler   +6 more
openaire   +2 more sources

Serum MMP-8 and TIMP-1 as prognostic biomarkers in gastric cancer

Tumor Biology, 2018
Despite gastric cancer being rare nowadays in Western countries, it remains one of the leading causes of cancer death worldwide. The course of the disease varies, so the individual gastric cancer patient’s prognosis is difficult to determine.
Alli Laitinen, Jaana Hagström, Harri Mustonen, Arto Kokkola, Taina Tervahartiala, Timo Sorsa, Camilla Böckelman, Caj Haglund   +7 more
doaj   +1 more source

Cell surface engineering of renal cell carcinoma with glycosylphosphatidylinositol-anchored TIMP-1 blocks TGF-beta 1 activation and reduces regulatory ID gene expression [PDF]

, 2012
Tissue inhibitor of metalloproteinase 1 (TIMP-1) controls matrix metalloproteinase activity through 1:1 stoichiometric binding. Human TIMP-1 fused to a glycosylphosphatidylinositol (GPI) anchor (TIMP-1-GPI) shifts the activity of TIMP-1 from the ...
Notohamiprodjo, Susan, Jaeckel, Carsten, Djafarzadeh, Roghieh, Hofstetter, Monika, Nelson, Peter J., Rieth, Nicole   +5 more
core   +1 more source

Relationships of MMP-9 and TIMP-1 proteins with chronic obstructive pulmonary disease risk: A systematic review and meta-analysis

Journal of Research in Medical Sciences, 2016
Background: We performed this meta-analysis in order to collect all the relevant studies to clarify the correlations of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) with chronic obstructive pulmonary disease ...
Yangxue Li, Yang Lu, Zhuo Zhao, Junnan Wang, Jianxin Li, Weiming Wang, Shumei Li, Lei Song   +7 more
doaj   +1 more source

Histopathologic Findings Associated With Matrix Metalloproteinases Proceeding to Recurrence of Primary Spontaneous Pneumothorax in Adolescents

Frontiers in Pediatrics, 2021
Background: Primary spontaneous pneumothorax is potentially life-threatening, and its recurrence is always a serious problem. Pathological examination provides molecular insights into the pathophysiology of primary spontaneous pneumothorax.Objectives: To
Chih-Yung Chiu, Jim-Ray Chen, Shun-Ying Yin, Chia-Jung Wang, Tzu-Ping Chen, Tsan-Yu Hsieh   +5 more
doaj   +1 more source

Expression of matrix metalloproteinase-1 and tissue inhibitor of metalloproteinase-1 in ulcerative colitis

World Journal of Gastroenterology, 2006
To examine the expression of metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in the colonic mucosa of patients with ulcerative colitis (UC).Reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry were used to study the expression of MMP-1 and TIMP-1 at both mRNA and protein levels in patients ...
Ying-De, Wang, Pei-Yun, Yan
openaire   +2 more sources