Stem Cells International, 2018 Mesenchymal stem cells (MSCs) are known for homing to sites of injury in response to signals of cellular damage. However, the mechanisms of how cytokines recruit stem cells to target tissue are still unclear.
Ming-Siou Chen +5 more
doaj +1 more source
N-Cadherin cleavage during activated hepatic stellate cell apoptosis is inhibited by tissue inhibitor of metalloproteinase-1. [In supplement: 11th International Symposium on the Cells of the Hepatic Sinusoid and their Relation to Other Cells] [PDF]
, 2004 Apoptosis of hepatic stellate cells (HSC) has previously been shown to occur during spontaneous resolution of experimental liver fibrosis. TIMP-1 has also been shown to have a key role because of its ability to inhibit apoptosis of HSC via matrix ...
Iredale, John P. +15 more
core +1 more source
Biomolecules & Biomedicine, 2009 Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a natural inhibitor of matrix metalloproteinas-es (MMPs). Aim of this study was to assess the immunohistochemical expression of TIMP-1 in invasive breast carcinomas, and to examine its association with
Suada Kuskunović +6 more
doaj +1 more source
Role of vascular remodeling markers in the development of osteoporosis in idiopathic pulmonary arterial hypertension [PDF]
Терапевтический архив, 2016 Aim. To define the role of circulating biomarkers for the metabolism of collagen and intercellular substance and vascular remodeling in the development of osteoporosis (OP) in idiopathic pulmonary arterial hypertension (IPAH).
V A Nevzorova +4 more
doaj +1 more source
Tissue inhibitor of metalloproteinases 1, a novel biomarker of tuberculosis
Molecular Medicine Reports, 2016 Tuberculosis (TB) is an important infectious disease of humans and other animals. Conventional diagnostic methods, including the tuberculin skin test, chest X‑rays and bacterial culture, have certain innate disadvantages for the early, rapid and specific diagnosis of tuberculosis.
Chen, Y. +9 more
openaire +3 more sources
Promoter variants in tissue inhibitor of metalloproteinase-3 (TIMP-3) protect against susceptibility in pigeon breeders' disease. [PDF]
, 2004 BACKGROUND: Tissue inhibitors of metalloproteinases (TIMPs) play a major role in extracellular matrix turnover in the lung. However, in chronic lung disorders such as idiopathic pulmonary fibrosis (IPF) and pigeon breeders' disease (PBD), TIMPs may ...
Briggs, L +7 more
core +1 more source
Tissue Inhibitor of Metalloproteinases-1 Regulation by Aldosterone [PDF]
Hypertension, 2016 See related article, pp 1309–1320 Primary aldosteronism (PA), first characterized by Conn in 1955,1 results in hypertension secondary to the excessive production of aldosterone by the adrenal cortex—in many cases because of the presence of a benign aldosterone-producing adenoma.
Criselda, Mendoza-Milla +1 more
openaire +2 more sources
Recombinant GPI-anchored TIMP-1 stimulates growth and migration of peritoneal mesothelial cells. [PDF]
, 2012 Mesothelial cells are critical in the pathogenesis of post-surgical intraabdominal adhesions as well as in the deterioration of the peritoneal membrane associated with long-term peritoneal dialysis.
Elfriede Noessner +43 more
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Journal of Medicine in Scientific Research, 2018 Background The imbalance between matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) may play an important role in impaired healing of diabetic foot ulcer.
Ghada H Sayed +4 more
doaj +1 more source
Assessment of the Biological Variation of Plasma Tissue Inhibitor of Metalloproteinases-1
The International Journal of Biological Markers, 2008 Background Tissue inhibitor of metalloproteinases-1 (TIMP-1) measurements in plasma may be useful for the early detection and prognosis of colorectal cancer (CRC). Data on analytical performance and normal intra- and interindividual biological variation are required in order to interpret the utility of TIMP-1 in
Frederiksen, C.B. +8 more
openaire +4 more sources