Results 41 to 50 of about 95,143 (290)

Role of vascular remodeling markers in the development of osteoporosis in idiopathic pulmonary arterial hypertension [PDF]

Терапевтический архив, 2016
Aim. To define the role of circulating biomarkers for the metabolism of collagen and intercellular substance and vascular remodeling in the development of osteoporosis (OP) in idiopathic pulmonary arterial hypertension (IPAH).
V A Nevzorova, E A Kochetkova, L G Ugay, Yu V Maistrovskaya, E A Khludeeva   +4 more
doaj   +1 more source

Immunohistochemical Expression of Tissue Inhibitor of Metalloproteinase-1 (Timp-1) in Invasive Breast Carcinoma

Biomolecules & Biomedicine, 2009
Tissue inhibitor of metalloproteinase-1 (TIMP-1) is a natural inhibitor of matrix metalloproteinas-es (MMPs). Aim of this study was to assess the immunohistochemical expression of TIMP-1 in invasive breast carcinomas, and to examine its association with
Suada Kuskunović, Svjetlana Radović, Mirsad Dorić, Ajna Hukić, Mirsad Babić, Ivana Tomić, Ivan Selak   +6 more
doaj   +1 more source

Matrix metalloproteinases and tissue inhibitor of metalloproteinase-1 in sarcoidosis and IPF [PDF]

European Respiratory Journal, 2002
The purpose of this study was to examine the role of interstitial collagenases, members of the family of matrix metalloproteinases, in the development of pulmonary fibrosis.The activity, levels and molecular forms of collagenases (matrix metalloproteinases (MMP)-1, -8 and -13), gelatinase B (MMP-9) and its main endogenous inhibitor, tissue inhibitor of
M T, Henry, K, McMahon, A J, Mackarel, K, Prikk, T, Sorsa, P, Maisi, R, Sepper, M X, Fitzgerald, C M, O'Connor   +8 more
openaire   +2 more sources

Association of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 levels with diabetic foot ulcer in Egyptians with type 2 diabetes mellitus

Journal of Medicine in Scientific Research, 2018
Background The imbalance between matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) may play an important role in impaired healing of diabetic foot ulcer.
Ghada H Sayed, Ghada A Omar, Ayat I Ghanem, Naglaa F Mohamed, Mourad I El-Kholy   +4 more
doaj   +1 more source

Assessment of the Biological Variation of Plasma Tissue Inhibitor of Metalloproteinases-1

The International Journal of Biological Markers, 2008
Background Tissue inhibitor of metalloproteinases-1 (TIMP-1) measurements in plasma may be useful for the early detection and prognosis of colorectal cancer (CRC). Data on analytical performance and normal intra- and interindividual biological variation are required in order to interpret the utility of TIMP-1 in
Frederiksen, C.B., Lomholt, A.F., Lottenburger, T., Davis, G.J., Dowell, B.L., Blankenstein, M.A., Christensen, I.J., Brunner, N., Nielsen, H.J.   +8 more
openaire   +4 more sources

Effect of Psoriasis Activity on Metalloproteinase‐1 and Tissue Inhibitor of Metalloproteinase‐1 in Plasma and Lesional Scales

Acta Dermato-Venereologica, 2005
The aim of this study was to evaluate the association between psoriasis severity and concentrations of matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in plasma and scales from psoriatic lesions, measured with an enzyme immunoassay in 24 patients and analysed with respect to psoriasis area and severity index ...
Iwona, Flisiak, Piotr, Porebski, Bozena, Chodynicka   +2 more
openaire   +2 more sources

Plasma matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 as prognostic biomarkers in critically ill patients

Open Medicine, 2020
Matrix metalloproteinase 9 (MMP-9) plays an important role in inflammatory and pathological processes by enabling the inflow of leukocytes to the site of infection or tissue damage.
Duda Izabela, Krzych Łukasz, Jędrzejowska-Szypułka Halina, Lewin-Kowalik Joana   +3 more
doaj   +1 more source

Plasma matrix metalloproteinase-1 and tissue inhibitor of metalloproteinases-1 as biomarkers of ulcerative colitis activity

World Journal of Gastroenterology, 2003
Overexpression of mucosal metalloproteinases (MMP) has been demonstrated recently in inflammatory bowel disease. Their activity can be counterbalanced by the tissue inhibitor of metalloproteinases (TIMP). The aim of this study was to evaluate the effect of ulcerative colitis (UC) on MMP-1 and TIMP-1 plasma concentrations, as two possible biomarkers of ...
Alicja, Wiercinska-Drapalo, Jerzy, Jaroszewicz, Robert, Flisiak, Danuta, Prokopowicz   +3 more
openaire   +2 more sources

Role of tissue inhibitor of metalloproteinases-1 in the development of autoimmune lymphoproliferation

Haematologica, 2010
Inherited defects decreasing function of the Fas death receptor cause autoimmune lymphoproliferative syndrome and its variant Dianzani's autoimmune lymphoproliferative disease. Analysis of the lymphocyte transcriptome from a patient with this latter condition detected striking over-expression of osteopontin and tissue inhibitor of metalloproteinases-1.
BOGGIO E, INDELICATO M, ORILIERI E, MESTURINI R, MAZZARINO MC, CAMPAGNOLI MF, RAMENGHI U, DIANZANI, Umberto, CHIOCCHETTI, Annalisa   +8 more
openaire   +5 more sources

Adiponectin Reduces Hepatic Stellate Cell Migration by Promoting Tissue Inhibitor of Metalloproteinase-1 (TIMP-1) Secretion*

Journal of Biological Chemistry, 2015
Background: Adiponectin has been shown to limit liver fibrosis, but the molecular mechanisms remain unknown. Results: In vitro and in vivo adiponectin increases TIMP-1 secretion, which binds to the CD63/β1-integrin complex to decrease FAK activity and ...
Mehdi Ramezani-Moghadam, Jianhua Wang, V. Ho, Tristan J. Iseli, Badr Alzahrani, A. Xu, D. K. van der Poorten, L. Qiao, J. George, Lionel Hebbard   +9 more
semanticscholar   +1 more source