Results 1 to 10 of about 31,315,155 (203)
A Case of Atrophic Dermatofibroma Overexpressing Matrix Metalloproteinase-1 [PDF]
Case Reports in Dermatology, 2019 This case report describes the importance of considering this tumor as one of the differential diagnoses when we encounter a flat and/or atrophic and depressible lesion in the upper portion of the trunk.
Atsuko Yano-Takamori +4 more
doaj +5 more sources
Matrix metalloproteinase 1: role in sarcoma biology. [PDF]
PLoS ONE, 2010 In carcinomas stromal cells participate in cancer progression by producing proteases such as MMPs. The expression MMP1 is a prognostic factor in human chondrosarcoma, however the role in tumor progression is unknown.
Muhammad Umar Jawad +6 more
doaj +4 more sources
Leptin and Pro-Inflammatory Stimuli Synergistically Upregulate MMP-1 and MMP-3 Secretion in Human Gingival Fibroblasts. [PDF]
PLoS ONE, 2016 Gingival fibroblast-mediated extracellular matrix remodelling is implicated in the pathogenesis of periodontitis, yet the stimuli that regulate this response are not fully understood.
Rachel C Williams +5 more
doaj +3 more sources
Patologìâ, 2023 Airway remodeling is a significant factor in the progression of respiratory failure in bronchial asthma (BA). Obesity can contribute to inflammation, and consequently – airway remodeling, by increased production of matrix proteinase (MMP).
V. V. Kachkovska, L. N. Prystupa
doaj +4 more sources
Mechanism of the Early Catalytic Events in the Collagenolysis by Matrix Metalloproteinase-1. [PDF]
Chemphyschem, 2023 AbstractThe front cover artwork is provided by Dr. Karabencheva‐Christova's group at Michigan Technological University. The images show the initially formed and the catalytically productive conformations of MMP‐1 complex with the Triple Helical Peptide (THP), the free energy profile connecting them as well as the coordination geometry of the catalytic ...
Waheed SO +6 more
europepmc +5 more sources
Changes in Serum Levels of Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinases-1 in Patients with Essential Hypertension. [PDF]
Bioengineering (Basel), 2022 Hypertension (HTN) is a leading risk factor for cardiovascular (CV) disease. Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are thought to be actively involved in the remodeling of the CV extracellular matrix (ECM) during hypertensive damage.
Kostov K, Blazhev A.
europepmc +4 more sources
Saudi Dental Journal, 2014 Background: Matrix metalloproteinase-1 (MMP-1) is a member of a family of enzymes that can degrade most extracellular matrix macromolecules. Extracellularly, MMPs are controlled by tissue inhibitors of metalloproteinases (TIMPs) and by mechanisms of pro ...
Pallavi S. Ghodpage +3 more
doaj +3 more sources
Frontiers in Mechanical Engineering, 2022 Chronic joint pain is a major health problem that can result from abnormal loading of the innervated ligamentous capsule that surrounds synovial joints.
Meagan E. Ita +2 more
doaj +1 more source
Matrix Metalloproteinase-1 and Matrix Metalloproteinase-9 in the Aqueous Humor of Diabetic Macular Edema Patients. [PDF]
PLoS ONE, 2016 To assess the concentrations of matrix metalloproteinase (MMP)-1 and MMP-9 in the aqueous humor of diabetic macular edema (DME) patients.The concentrations of MMP-1 and MMP-9 in the aqueous humors of 15 cataract patients and 25 DME patients were compared.
Jin-Woo Kwon, Jin A Choi, Donghyun Jee
doaj +1 more source
Role of matrix metalloproteinases 1, 2, and 9 and tissue inhibitor of matrix metalloproteinase-1 in chronic venous insufficiency [PDF]
Journal of Vascular Surgery, 2001 Increased transforming growth factor-beta(1) (TGF-beta(1)) activity is associated with chronic venous insufficiency (CVI) disease progression and dermal skin pathology. Because TGF-beta(1) stimulates collagen synthesis and alters the levels of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs), we investigated the hypothesis that increased ...
Saito, Satoshi +8 more
openaire +2 more sources