Results 41 to 50 of about 246,662 (308)

Levels of matrix metalloproteinase-1 and tissue inhibitors of metalloproteinase-1 in gastric cancer

World Journal of Gastroenterology, 2011
To evaluate the levels of preoperative serum matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in gastric cancer.One hundred gastric cancer patients who underwent gastrectomy were enrolled in this study. The serum concentrations of MMP-1 and TIMP-1 in these patients and in fifty healthy controls were determined ...
Yılmaz, Özkan, KISLI, Erol, Begenik, Hüseyin, ADAS, Mine, HASIRCI, Ismail, Kemik, Ahu Sarbay, Dulger, Ahmet Cumhur, TUZUN, Sefa, KOTAN, Cetin, Kemik, Özgür, SUMER, Aziz, PURISA, Sevim   +11 more
openaire   +3 more sources

Low MMP-8/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIM P-1 may help to differentiate it from acute coronary syndrome [PDF]

, 2017
Background Matrix metalloproteinase 8 (MMP-8) is the most potent type-I collagen protease. Such collagen mainly constitutes the transient fibrosis in takotsubo cardiomyopathy (TTC) endomyocardial biopsies.
Jousilahti, Pekka, Nieminen, Mikko Tapani, Parkkonen, Olavi, Perola, Markus, Pussinen, Pirkko, Salomaa, Veikko, Sinisalo, Juha-Pekka, Sorsa, Timo, Tervahartiala, Taina, Vesterinen, Paula   +9 more
core   +4 more sources

Matrix metalloproteinase-9, its inhibitor-1 and interleukines in experimental traumatic brain injury

Patologìâ, 2016
Traumatic brain injury (TBI) is accompanied by high rates of morbidity and mortality in both developed and undeveloped countries that makes it one of the most actual medical and social problems. In recent years matrix metalloproteinases are in increasing
S. V. Ziablitsev, Ya. S. Yuzkiv
doaj   +1 more source

Matrix metalloproteinases at key junctions in the pathomechanism of stroke [PDF]

, 2011
Matrix metalloproteinases play a crucial role in the remodelling of the extracellular matrix through direct degradation of its structural proteins and control of extracellular signaling.
Amento, Ang, Asahi, Asahi, Barkho, Bergers, Bini, Cao, Cardone, Chinopoulos, Cunningham, Denker, Dong, Fabunmi, Fisher, Frisch, Galis, Galis, Galis, Galis, Gidday, Godin, Gross, Gu, Gu, Gurney, Haas, Haddad, Halliwell, Hamann, Harkness, Herman, Hornig, Hyslop, Itoh, Kumura, Langton, Lapchak, Larsen, Lee, Lelongt, Loftus, Lucivero, Luttun, McQuibban, Meredith, Montaner, Montaner, Nagase, Nagel, Nagy, Nagy, Nikkari, Pagenstecher, Qi, Rajagopalan, Ramos, Rekhter, Rolfe, Romanic, Rosell, Rosenberg, Rosenberg, Rosenberg, Rosenberg, Sarén, Sato, Seo, Shrivastava, Shubayev, Siao, Sole, Sottrup, Sternlicht, Strongin, Sukhova, Suzuki, Suzuki, Svedin, Tsuji, Turner, Van, Vogel, Wang, Wang, Webersinke, Yepes, Ying, Zhang, Zhang, Zhang, Zhao   +91 more
core   +1 more source

Interdomain Flexibility in Full-length Matrix Metalloproteinase-1 (MMP-1) [PDF]

Journal of Biological Chemistry, 2009
The presence of extensive reciprocal conformational freedom between the catalytic and the hemopexin-like domains of full-length matrix metalloproteinase-1 (MMP-1) is demonstrated by NMR and small angle x-ray scattering experiments. This finding is discussed in relation to the essentiality of the hemopexin-like domain for the collagenolytic activity of ...
BERTINI, IVANO, FRAGAI, MARCO, LUCHINAT, CLAUDIO, MELIKIAN, MAXIME THIERRY OLIVIER, E. Mylonas, SARTI, NIKO, D. Svergun   +6 more
openaire   +3 more sources

Assessment of Matrix Metalloproteinases a Prognostic Indicator in Advanced Fibrotic Lung Disease: A Systematic Review

Pakistan Journal of Medicine and Dentistry
Background: Fibrotic lung diseases were seen to have devastating effects among patients globally. Matrix metalloproteinases (MMP) including MMP-7, MMP-9, and MMP-1 have become promising biomarkers for idiopathic pulmonary fibrosis (IPF), and other ...
Mehvish Aqil, Saif Ur Rahman, Muhammad Zeeshan Aslam, Mostafa Ahmed Abdellah Ahmed, Ammar Ahmed, Sidra Javaid, Ehsan Ul Haq   +6 more
doaj   +1 more source

Plasma matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 as prognostic biomarkers in critically ill patients

Open Medicine, 2020
Matrix metalloproteinase 9 (MMP-9) plays an important role in inflammatory and pathological processes by enabling the inflow of leukocytes to the site of infection or tissue damage.
Duda Izabela, Krzych Łukasz, Jędrzejowska-Szypułka Halina, Lewin-Kowalik Joana   +3 more
doaj   +1 more source

Matrix metalloproteinases in liver injury, repair and fibrosis. [PDF]

, 2015
The liver is a large highly vascularized organ with a central function in metabolic homeostasis, detoxification, and immunity. Due to its roles, the liver is frequently exposed to various insults which can cause cell death and hepatic dysfunction ...
Baber, John, Coito, Ana J, Duarte, Sergio, Fujii, Takehiro   +3 more
core   +1 more source

Expression of matrix metalloproteinase-2 and 9 with their inhibitors, tissue inhibitors of metalloproteinase-1 and 2 in oral lichen planus

Journal of Orofacial Sciences, 2014
Objectives: The study aims to explore the expression of the matrix metalloproteinases (MMP-2, -9) and their inhibitors (tissue inhibitors of metalloproteinase [TIMP]-1, -2) as well as the correlation between them in the different morphological forms of ...
Natheer Hashim Al-Rawi, Thaer Kassim Al-Kassam, Ahlam Hameed Majeed   +2 more
doaj   +1 more source

Histopathologic Findings Associated With Matrix Metalloproteinases Proceeding to Recurrence of Primary Spontaneous Pneumothorax in Adolescents

Frontiers in Pediatrics, 2021
Background: Primary spontaneous pneumothorax is potentially life-threatening, and its recurrence is always a serious problem. Pathological examination provides molecular insights into the pathophysiology of primary spontaneous pneumothorax.Objectives: To
Chih-Yung Chiu, Jim-Ray Chen, Shun-Ying Yin, Chia-Jung Wang, Tzu-Ping Chen, Tsan-Yu Hsieh   +5 more
doaj   +1 more source