Results 171 to 180 of about 191,310 (286)

Evaluation of a research use only (RUO) TIMP-1 assay for use with the automated Alinity <i>i</i> platform. [PDF]

Biochem Biophys Rep
Anderson M, Grieshaber J, Ortiz J, Baclig M, Pacenti G, Munoz J, Rudolph C, Otis K, Corby J, Prostko J, Hemken P.   +10 more
europepmc   +1 more source

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, Volume 38, Issue 27, 14 May 2026.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

ADAMTS-7 Increase Contributes to Worsened Neurological Outcome in Mice on High Fat Diet. [PDF]

CNS Neurosci Ther
Xu Y, Li J, Zuo Z.
europepmc   +1 more source

Neuroprotective Properties of Litchi chinensis and Its Phytochemicals in Preclinical Models of Alzheimer's Disease

Brain and Behavior, Volume 16, Issue 5, May 2026.
ABSTRACT Purpose Alzheimer's disease (AD) is a progressive neurodegenerative disorder involving amyloid‐β deposition, tau hyperphosphorylation, oxidative stress, and neuroinflammation. This review systematically evaluates the neuroprotective effects of Litchi chinensis and its phytochemicals against AD, focusing on modulation of Aβ accumulation, tau ...
Emon Mia, Md. Arif Hossain, Asmaul Husna Bristy, Rakib Hossan, Uzma Asif, Asif Khan Sherwani, Mohammad Y. Alshahrani, Samy Selim, Imam Hossen Rakib, Noshin Tasnim Yana, Khadija Akter, Md. Sakib Al Hasan   +11 more
wiley   +1 more source

Urinary cell cycle arrest biomarkers TIMP-2 and IGFBP7 for the assessment of acute kidney injury in dogs with pyometra. [PDF]

Front Vet Sci
Braz LADN, Maia SR, Gasser B, Cruz NDRN, Alvarenga AWO, Soares LV, Uscategui RAR, de Nardi AB, Crivellenti LZ.   +8 more
europepmc   +1 more source

Diagnostic and Therapeutic Roles of Extracellular Vesicles in Chronic Kidney Disease: A Systematic Review

Journal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
This systematic review compiles and analyses 364 studies on chronic kidney disease (CKD) that investigated extracellular vesicles (EVs) for diagnostic and therapeutic applications. By systematically categorizing data according to EV source and cargo, it provides an integrated overview of EV application for CKD, highlighting common approaches and shared
Tunahan Ergunay, Alessia Brossa, Benedetta Bussolati   +2 more
wiley   +1 more source

Glycosaminoglycan-functionalized hydrogels for sustained delivery of tissue inhibitor of metalloproteinase-3 mediating matrix metalloprotease inhibition and extracellular matrix stabilization. [PDF]

Bioact Mater
Junker F, Rupf S, Schindler PM, Wilden C, Hohl M, Ruiz-Gómez G, Pisabarro MT, Wrublewsky S, Bickelmann C, Berhorst C, Alansary D, Wieland B, Bischoff M, Lee PS, Moeller S, Berg A, Dancker TA, Lauterbach MA, Ganse B, Roma LP, Steudter T, Metzger W, Tschernig T, Ampofo E, Laschke MW, Hannig M, Rother S.   +26 more
europepmc   +1 more source

Extracellular Vesicles in Osteoarthritis: From Pathogenic Mediators to Engineered Therapeutics in a Precision Medicine Roadmap

Journal of Extracellular Biology, Volume 5, Issue 5, May 2026.
ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach, Van Giang Bui, Thanh Liem Nguyen   +2 more
wiley   +1 more source

The association of multiple sclerosis with systemic inflammatory biomarkers: A case-control study exploring links with periodontal disease. [PDF]

J Oral Biol Craniofac Res
Abed OK, Abbas RF.
europepmc   +1 more source

Analysis of the Matrix Metalloproteinases Family Profile in Gastric Cancer Suggests Key Matrix Metalloproteinases for Tumor Development and Their Clinical Impact

Molecular Carcinogenesis, Volume 65, Issue 5, Page 577-588, May 2026.
ABSTRACT Gastric cancer (GC) is the fifth most common type worldwide, representing a public health problem. Among the genes related to this tumorigenesis, the family of matrix metalloproteinases (MMPs), essential regulators of the extracellular matrix (ECM), stand out for their involvement in the development and progression of GC.
Aline Costa Bastos, André Salim Khayat, Emanuele Raimunda Louzada Moraes, Ágatha Tereza Miranda Tavares, Ronald Matheus da Silva Mourão, Fabiano Cordeiro Moreira, Samir Mansour Moraes Casseb, Samia Demachki, Geraldo Ishak, Williams Fernandes Barra, Rommel Mario Rodríguez Burbano, Paulo Pimentel de Assumpção   +11 more
wiley   +1 more source