Results 171 to 180 of about 141,946 (275)

Extracellular Vesicles Drive Invasive Characteristics and Matrix Remodelling in Organotypic Models of Colorectal Cancer Progression

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer‐related mortality, with metastasis accounting for over 90% of CRC deaths. While the role of extracellular vesicles (EVs) in cancer progression is recognised, their impact on invasive behaviour and extracellular matrix (ECM) remodelling within physiologically relevant three‐dimensional ...
Sonia Guarnerio, Laura Cole, Rawan Maani, Rob Tempest, Alex Mirnezami, Paul Hughes, Stuart Hunt, Christine Le Maitre, Keith Chapple, Nick Peake   +9 more
wiley   +1 more source

Matrix Metalloproteinases and Cardiac Remodelling in Smokers with Acute Coronary Syndrome. [PDF]

Int J Mol Sci
Aminuddin A, Samah N, Nor FM, Wan Razali WMH, Cong BB, Mohamad SF, Hamid AA, Norhisham WK, Ugusman A.   +8 more
europepmc   +1 more source

European Society for Pediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) steatotic liver disease special interest group position paper on screening, diagnosis and investigation of paediatric metabolic dysfunction‐associated steatotic liver disease

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 555-576, September 2026.
Abstract Metabolic dysfunction‐associated steatotic liver disease (MASLD) is the most common reason for elevated liver enzymes in children in Europe, affecting more than 5% of all children. Since the last iteration of this position paper, there have been substantial advances in our understanding of the disease.
Jake P. Mann, Sander Lefere, Maarten Buytaert, Anna Alisi, Cigdem Arikan, Jernej Brecelj, Rachel M. Brown, Irene Degrassi, Giulia Fiore, Emer Fitzpatrick, Sven Francque, Christian A. Hudert, Wojciech Janczyk, Lauren Johansen, Bart G. Koot, Anastasia Konidari, Eberhard Lurz, Claudia Mandato, Maria Mercadal‐Hally, Hadar Moran‐Lev, Antonella Mosca, Giusy Ranucci, Maria Rogalidou, Penelope C. Rose, Piotr Socha, Pietro Vajro, Elvira Verduci, Anita C. E. Vreugdenhil, Natalia Zavhorodnia, Aglaia Zellos, Ruth De Bruyne   +30 more
wiley   +1 more source

Growth Plate Morphogens as Potential Modulators of Cellular Tissue Remodeling by Annulus Fibrosus Cells

JOR SPINE, Volume 9, Issue 3, September 2026.
ABSTRACT Background Adolescent Idiopathic Scoliosis (AIS) is a spinal deformity of unknown etiology that begins in the intervertebral disc and emerges during pubertal growth. In the vertebral growth plate, adjacent to the disc, powerful growth plate morphogens (GPMs) modulate this growth. We evaluated whether GPMs can also alter the capacity of annulus
K. Stradovnik‐Poikilidis, M. Teunissen, F. M. Riemers, M. van Doeselaar, J. Foolen, F. Abinzano, M. A. Tryfonidou, S. J. P. Callens, K. Ito   +8 more
wiley   +1 more source

An Exploratory Study of Vitamin D and Matrix Metalloproteinase and Their Regulators in Polyendocrine Metabolic Ovarian Syndrome. [PDF]

Pharmaceuticals (Basel)
Zainalabedin M, Smahi N, Sathyapalan T, Butler AE, Atkin SL.   +4 more
europepmc   +1 more source

Inflammatory Bowel Disease: Mechanisms and Therapeutic Advances

MedComm, Volume 7, Issue 9, September 2026.
Inflammatory bowel disease (IBD), encompassing ulcerative colitis and Crohn's disease, is a rising, multifactorial chronic disorder driven by dysregulated mucosal immunity in genetically susceptible individuals and influenced by environmental and microbial factors.
Andrea Papait, Anna Cargnoni, Franco Scaldaferri, Loris Lopetuso, Antonietta Rosa Silini, Ornella Parolini   +5 more
wiley   +1 more source

Extracorporeal Shock Wave Therapy in Knee Osteoarthritis: A Mechanistic Narrative Review of Neurogenic Inflammation and the MMP/ADAMTS Axis. [PDF]

Int J Gen Med
Guo Z, Yuan Y, Su H, Dong J.
europepmc   +1 more source

Heat Shock Proteins in Cancer: Mechanisms and Therapeutic Targeting

MedComm, Volume 7, Issue 9, September 2026.
This review illustrates heat shock proteins (HSPs) as central regulators of cancer metabolic reprogramming. By stabilizing key metabolic enzymes and coordinating glycolysis, oxidative phosphorylation, redox homeostasis, and stress adaptation, HSPs support tumor growth, metastasis, and therapeutic resistance. Targeting HSP networks may therefore provide
Sheng Ma, Chen‐Qian Liu, Si‐Yang Ma, Shao‐Gang Wang, Qi‐Dong Xia, Meng‐Yao Xu   +5 more
wiley   +1 more source

Use of [TIMP-2] • [IGFBP7] to identify sepsis-related acute kidney injury in the emergency department. [PDF]

Ann Intensive Care
Cisteró B, Monforte V, Navas A, Tomasa-Irriguible TM, Camprubí-Rimblas M, Areny-Balagueró A, Campaña-Duel E, Martin I, Tomas A, Miñarro I, Vila M, Cuevas M, Teles T, Savone M, Stable C, Salom P, Guijarro C, Tajan J, Goma G, Diaz E, Blanch L, Gene E, Ostermann M, Kellum JA, Honore PM, Artigas A, Ceccato A.   +26 more
europepmc   +1 more source

Expression of TIMP-2 in HPV-16 infected oral squamous cell carcinoma in patients in Iraq

determine the expression of tissue inhibitors of metalloproteinases (TIMP-2) in oral squamous cell carcinoma (OSCC) and the difference in its expression level between positive and negative HPV-16 (human papilloma virus- 16) OSCC patients.
Habib A Manal, Habib A Huda, Hussain A Israa, Karima Al-Salihi
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