Results 131 to 140 of about 337,177 (299)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Tin-doped perovskite mixed conducting membrane for efficient air separation

, 2014
In this study, we propose a new tin-doped perovskite oxide, BaCo0.7Fe0.2Sn0.1O3-δ (BCFSn0.1), as a promising alternative material for a ceramic oxygen-permeating membrane.
Y. Hao (7758140), Y. Chen (6162), Shaomin Liu (566712), Zongping Shao (1440175), Moses Tade (1664692), Z. Zhang (551978)   +5 more
core  

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Tin-based composite anodes for potassium-ion batteries

, 2016
An anode based on the tetragonal tin (Sn) phase that can alloy electrochemically with potassium is demonstrated for potassium-ion batteries.
Ying (Ian) Chen (13074204), T Ramireddy (13346832), I Sultana (13434186), AM Glushenkov (15794987), Md Mokhlesur Rahman (13090230)   +4 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Influence of TiN-coatings of hard alloy knives on exploitation of wood-cutting milling tool when processing laminated chipboard

, 2020
The influence of TiN-coatings surface of cutters mill wood tools on wear of cutters for milling special woods was investigated. The TiN-coatings were formed on surfaces of import cutting inserts of mill tools by the method of condensation from a plasma
Garanin, V. N., Grishkevich, A. A., Chayevski, V. V., Alifanov, A. V.   +3 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

A new osteoporotic animal model for implant-related infected non-unions after intramedullary fixation of the femur

Bone Reports, 2020
Ronald Man Yeung Wong, Jie Li, Tsz Kiu Li, Simon Kwoon Ho Chow, Margaret Ip, Wing-Hoi Cheung   +5 more
doaj   +1 more source

Kidney Involvement in Primary Sjögren Syndrome: Focus on Tubulointerstitial Nephritis. [PDF]

Medicina (Kaunas)
Giannese D, Moriconi D, La Rocca G, Ceccarelli L, Migliorini P, Della Buona I, Giannini A, Bonadio AG, Ferro F, D'Elios S, Ricchiuti G, D'Alessandro C, Panichi V, Baldini C.   +13 more
europepmc   +1 more source