Results 51 to 60 of about 46,934 (254)

Evaluating the Effects of Blade Tip Clearance in Various Stages on the Performance of an Axial Compressor

open access: yesJournal of Applied Fluid Mechanics, 2018
In the current study, the influence of blade tip clearance in different stages of a three-stage compressor is investigated. Performance diagrams of compressor were verified against experiment when there is no change in the tip clearance, after which the ...
M. Ostad, R. Kamali
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

An Investigation on the Effect of Blade Tip Clearance on the Performance of a Single-Stage Axial Compressor

open access: yesJournal of Applied Fluid Mechanics, 2019
In the present study, the numerical analysis of blade tip geometry effect on the performance of a single-stage axial compressor has been the focus of attention. The studied geometries included a rotor with variable tip clearance. For the first model, the
M. Ostad, R. Kamali
doaj  

Design of Tip Clearance in the D.D.I. Process to Manufacture Pressure Vessel [PDF]

open access: yes한국정밀공학회지, 2018
The liner of CNG pressure vessel was manufactured using a deep drawing and ironing (D.D.I.) process with a single punch. Tip clearance between billet and die suggested in the actual field has been widely used to reduce forming load and to improve die ...
Hyo Seo Kwak, Gun Young Park, Chul Kim
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Flow and Fast Fourier Transform Analyses for Tip Clearance Effect in an Operating Kaplan Turbine

open access: yesEnergies, 2019
The Kaplan turbine is an axial propeller-type turbine that can simultaneously control guide vanes and runner blades, thus allowing its application in a wide range of operations.
Hyoung-Ho Kim   +3 more
doaj   +1 more source

Numerical Investigation on Flow Field Distribution of Eccentric Compressors Based on Steady and Unsteady CFD Methods

open access: yesEnergies, 2020
The tip clearance has an important effect on the performance of an engine compressor. While the impact of tip clearance on a concentric compressor has been widely explored in previous research, the flow field distribution of an eccentric compressor has ...
Chao Jiang   +3 more
doaj   +1 more source

Blade Serial Number Identification Based on Blade Tip Clearance without OPR Sensor

open access: yesShock and Vibration, 2021
Blade serial number identification is one of the key issues in blade tip-timing vibration measurement without once-per-revolution (OPR) sensor. In order to overcome the shortcomings of the existing blade serial number identification methods without OPR ...
Liang Zhang   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Effects of a Nonuniform Tip Clearance Profile on the Performance and Flow Field in a Centrifugal Compressor

open access: yesInternational Journal of Rotating Machinery, 2012
This paper presents a numerical investigation of the effects of a nonuniform tip clearance profile on the performance and flow field in a centrifugal compressor with a vaneless diffuser.
Yohan Jung   +3 more
doaj   +1 more source

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