Results 51 to 60 of about 49,035 (213)

Effects of a Nonuniform Tip Clearance Profile on the Performance and Flow Field in a Centrifugal Compressor

open access: yesInternational Journal of Rotating Machinery, 2012
This paper presents a numerical investigation of the effects of a nonuniform tip clearance profile on the performance and flow field in a centrifugal compressor with a vaneless diffuser.
Yohan Jung   +3 more
doaj   +1 more source

Flow and Fast Fourier Transform Analyses for Tip Clearance Effect in an Operating Kaplan Turbine

open access: yesEnergies, 2019
The Kaplan turbine is an axial propeller-type turbine that can simultaneously control guide vanes and runner blades, thus allowing its application in a wide range of operations.
Hyoung-Ho Kim   +3 more
doaj   +1 more source

Numerical Investigation on Flow Field Distribution of Eccentric Compressors Based on Steady and Unsteady CFD Methods

open access: yesEnergies, 2020
The tip clearance has an important effect on the performance of an engine compressor. While the impact of tip clearance on a concentric compressor has been widely explored in previous research, the flow field distribution of an eccentric compressor has ...
Chao Jiang   +3 more
doaj   +1 more source

Blade Serial Number Identification Based on Blade Tip Clearance without OPR Sensor

open access: yesShock and Vibration, 2021
Blade serial number identification is one of the key issues in blade tip-timing vibration measurement without once-per-revolution (OPR) sensor. In order to overcome the shortcomings of the existing blade serial number identification methods without OPR ...
Liang Zhang   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Energy Performance and Radial Force of a Mixed-Flow Pump with Symmetrical and Unsymmetrical Tip Clearances

open access: yesEnergies, 2017
The energy performance and radial force of a mixed flow pump with symmetrical and unsymmetrical tip clearance are investigated in this paper. As the tip clearance increases, the pump head and efficiency both decrease.
Yue Hao   +5 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A Review of Tip Clearance in Propeller, Pump and Turbine

open access: yesEnergies, 2018
Propellers, pumps, and turbines are widely applied in marine equipment, water systems, and hydropower stations. With the increasing demand for energy conservation and environmental protection, the high efficiency and the stable operation of pumps and ...
Yabin Liu, Lei Tan, Binbin Wang
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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