Results 41 to 50 of about 46,934 (254)
A review of blade tip clearance–measuring technologies for gas turbine engines
Measurement + Control, 2020 Blade tip clearance is one of the important parameters affecting the performance, safety and stability of a gas turbine engine. However, it is difficult to measure the tip clearance in real time and accurately during the development and test process of ...
Bing Yu +3 more
doaj +1 more source
Scientific Reports, 2022 In a multiphase pump, tip clearance is the required distance between the blade tip and the pump body wall of the impeller, forming tip leakage vortex (TLV), causing unstable flow and energy dissipation.
Zekui Shu +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Journal of Applied Fluid Mechanics, 2020 The impact of varying the tip clearance of each rotor on the performance of a counter-rotating axial compressor has been investigated based on numerical simulations.
T. Liang +4 more
doaj
Nihon Kikai Gakkai ronbunshu, 2023 Using a high-speed multistage scale model compressor simulating a middle stage of a gas turbine compressor for power generation, the effects of 3 types of rotor tip clearances on performance and operating range, and the vortex structure of rotor tip ...
Ryosuke SEKI
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Influence of Tip Clearance on Pressure Fluctuation in Low Specific Speed Mixed-Flow Pump Passage
Energies, 2017 To explore the influence of tip clearance on pressure fluctuation in a low specific speed mixed-flow pump, tip clearances δ of 0.25 mm, 0.75 mm and 1.00 mm, along with no tip clearance, were selected.
Wenwu Zhang, Zhiyi Yu, Baoshan Zhu
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source