Results 151 to 160 of about 35,159 (258)

Writing Big in Plant Genomes: Advances, Challenges and Strategies for Targeted Large‐Fragment DNA Insertion

Plant, Cell &Environment, EarlyView.
ABSTRACT Precise genome editing has transformed plant biology and crop improvement by enabling targeted modification of endogenous loci. Beyond gene knockout and base editing, the site‐specific insertion of exogenous DNA, particularly large DNA fragments, has become a central goal for engineering complex traits, reconstructing metabolic pathways and ...
Fengfeng Zhang, Daqi Yan, Jiayi Hou, Dan Yang, Yan Xiong, Mingzhang Wen, Xiaoyue Zhu   +6 more
wiley   +1 more source

Reconstructing the TIR side of the Myddosome: a paradigm for TIR-TIR interactions?

, 2015
Vyncke, Laurens, Bovijn, Celia, Pauwels, Ewald, Van Acker, Tim, Ruyssinck, Elien, Tavernier, Jan, Peelman, Frank   +6 more
openaire   +1 more source

Chemical treatment rescues reduced growth of the autoimmune mutant chs3‐2D without compromising its immune responses

Plant Biology, EarlyView.
We generated a compound by chemical modification that can efficiently rescue growth without decreasing the immune response of the chs3‐2D autoimmune mutants, thus chemically uncoupling its growth–defence trade‐off. Abstract Plant development in many species including Arabidopsis relies on the accurate balance between growth and defence.
M. Keijzer, M. Liebers, J. Seufer, L. Voll, C. Meier, S. Hoth   +5 more
wiley   +1 more source

A Hospital-Wide informatized glycemic management Team(WH-GMT) improves perioperative outcomes in type 2 diabetes: A prospective cohort study. [PDF]

Endocrine
Zhou Q, Pan X, Zhang X, Huang D.
europepmc   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Efficacy and Safety of Open-Source Hybrid Closed-Loop Automated Insulin Delivery in Perioperative Patients. [PDF]

Biomedicines
Ma D, Xu W, Yang Y, Bai L, Xie J, Tao J, Xu S, Dong K, Shi X, Song X, Zhu Y, Sun N, Huang G, Liu F, Hu X, Li J, Li M, Ao T, Yuan J, Yu X, Liu Z.   +20 more
europepmc   +1 more source

‘Who is the Gael who Would Not Weep?’: The Book of the O’Conor Don, Fearghal Óg Mac an Bhaird, and Late Bardic Poetry of Exile

Renaissance Studies, EarlyView.
Abstract This article examines how late bardic poetry transforms the condition of exile into a literary mode that reimagines community and tradition. I argue that poetry of lament, blessing and devotion articulates a broader literary consciousness that anticipates modern notions of a national consciousness. The compilation of bardic verse in manuscript
Daniel T. McClurkin
wiley   +1 more source

Impact of Missing Data and Monitoring Duration on Downstream Analyses in Continuous Glucose Monitoring. [PDF]

Diabetes Care
Kok N, Williamson WT, Lee JM, Gaynanova I.   +3 more
europepmc   +1 more source

Histiocytes: Multifaceted Regulators of Health and Disease

Veterinary Clinical Pathology, EarlyView.
ABSTRACT The mononuclear phagocyte system encompasses macrophages, dendritic cells (DCs), and monocytes. Tissue‐resident macrophages and dendritic cells arise during embryogenesis and are replenished either through self‐renewal or by monocytes during inflammation.
Erika J. Gruber
wiley   +1 more source