Results 31 to 40 of about 9,791 (194)

TIR1-produced cAMP as a second messenger in transcriptional auxin signalling. [PDF]

Nature
Abstract The phytohormone auxin (Aux) is a principal endogenous developmental signal in plants. It mediates transcriptional reprogramming by a well-established canonical signalling mechanism. TIR1/AFB auxin receptors are F-box subunits of an ubiquitin ligase complex; after auxin perception, they associate with Aux/IAA transcriptional ...
Chen H, Qi L, Zou M, Lu M, Kwiatkowski M, Pei Y, Jaworski K, Friml J.   +7 more
europepmc   +3 more sources

Auxin-induced SCFTIR1-Aux/IAA interaction involves stable modification of the SCFTIR1 complex [PDF]

, 2004
The plant hormone auxin can regulate gene expression by destabilizing members of the Aux/IAA family of transcriptional repressors. Auxin-induced Aux/IAA degradation requires the protein-ubiquitin ligase SCFTIR1, with auxin acting to enhance the ...
Abel, Berleth, Deshaies, Dharmasiri, Gray, Gray, Hennig, Kepinski, O. Leyser, Ouellet, Ramos, Rouse, Ruegger, S. Kepinski, Tian, Tiwari, Ulmasov, Yoshida, Zenser   +18 more
core   +2 more sources

A spontaneous TIR1 loss-of-function allele in C. elegans

microPublication biology, 2023
The auxin-inducible degron (AID) system is a widely-used system for conditional protein depletion. During the course of an experiment, we depleted the nuclear hormone receptor transcription factor NHR-23 to study molting, and we recovered a spontaneous suppressor allele that bypassed the L1 larval arrest caused by NHR-23 depletion.
Myles, Krista M., Vo, An A., Ragle, James Matthew, Ward, Jordan D.   +3 more
openaire   +2 more sources

MiR393 regulation of auxin signaling and redox-related components during acclimation to salinity in Arabidopsis. [PDF]

PLoS ONE, 2014
One of the most striking aspects of plant plasticity is the modulation of development in response to environmental changes. Plant growth and development largely depend on the phytohormone auxin that exerts its function through a partially redundant ...
María José Iglesias, María Cecilia Terrile, David Windels, María Cristina Lombardo, Carlos Guillermo Bartoli, Franck Vazquez, Mark Estelle, Claudia Anahí Casalongué   +7 more
doaj   +1 more source

Auxin regulates SCFTIR1-dependent degradation of AUX/IAA proteins [PDF]

, 2001
The plant hormone auxin is central in many aspects of plant development. Previous studies have implicated the ubiquitin-ligase SCFTIR1 and the AUX/IAA proteins in auxin response.
Estelle, M., Gray, W.M., Kepinski, S., Leyser, O., Rouse, D.   +4 more
core   +1 more source

Molecular genetics of auxin signaling [PDF]

, 2002
The plant hormone auxin is a simple molecule similar to tryptophan, yet it elicits a diverse array of responses and is involved in the regulation of growth and development throughout the plant life cycle.
Leyser, O
core   +1 more source

Plasma membrane association by N-acylation governs PKG function in Toxoplasma gondii [PDF]

, 2017
Cyclic GMP (cGMP)-dependent protein kinase (protein kinase G [PKG]) is essential for microneme secretion, motility, invasion, and egress in apicomplexan parasites, However, the separate roles of two isoforms of the kinase that are expressed by some ...
Brown, Kevin M, Long, Shaojun, Sibley, L. David   +2 more
core   +2 more sources

Chemical hijacking of auxin signaling with an engineered auxin–TIR1 pair [PDF]

Nature Chemical Biology, 2018
The phytohormone auxin indole-3-acetic acid (IAA) regulates nearly all aspects of plant growth and development. Despite substantial progress in our understanding of auxin biology, delineating specific auxin response remains a major challenge. Auxin regulates transcriptional response via its receptors, TIR1 and AFB F-box proteins.
Naoyuki Uchida, Koji Takahashi, Rie Iwasaki, Ryotaro Yamada, Masahiko Yoshimura, Takaho A Endo, Seisuke Kimura, Hua Zhang, Mika Nomoto, Yasuomi Tada, Toshinori Kinoshita, Kenichiro Itami, Shinya Hagihara, Keiko U Torii   +13 more
openaire   +2 more sources

HSP90 stabilizes auxin receptor TIR1 and ensures plasticity of auxin responses [PDF]

Plant Signaling & Behavior, 2017
Heat shock protein 90 (HSP90) is a highly conserved molecular chaperone that facilitates the maturation of target proteins. Here, we report that the auxin receptor TIR1 is a target of cytosolic HSP90 and that HSP90 and TIR1 form a complex. Inhibition of HSP90 compromised the nuclear localization of TIR1, and abrogated plant responses to the hormone ...
Etsuko Watanabe, Shoji Mano, Ikuko Hara-Nishimura, Mikio Nishimura, Kenji Yamada   +4 more
openaire   +3 more sources

The eta7/csn3-3 auxin response mutant of Arabidopsis defines a novel function for the CSN3 subunit of the COP9 signalosome. [PDF]

PLoS ONE, 2013
The COP9 signalosome (CSN) is an eight subunit protein complex conserved in all higher eukaryotes. In Arabidopsis thaliana, the CSN regulates auxin response by removing the ubiquitin-like protein NEDD8/RUB1 from the CUL1 subunit of the SCF(TIR1/AFB ...
He Huang, Marcel Quint, William M Gray
doaj   +1 more source