Results 111 to 120 of about 12,125 (226)

Tirofiban Preserves Endothelial Junctions and Decreases Endothelin-1

, 2008
It has been verified that glycoprotein IIb/IIIa inhibitor tirofiban can attenuate myocardial no-reflow. Myocardial no-reflow has been associated with alterations in endothelial junctions.
Yue-Jin YANG, Run-Lin GAO, Ya-Xin LIU, Mei ZHAI, Yu-Hua SUN, Wei-Dong PEI, Jing-Lin Zhao   +6 more
core   +1 more source

Intravenous Thrombolysis Plus Tirofiban in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis.

Journal of Emergency Medicine
BACKGROUND Acute ischemic stroke is a cerebrovascular disease associated with high disability and mortality. Tirofiban, a platelet glycoprotein IIb/IIIa receptor antagonist, is used in conjunction with IV thrombolysis for bridging therapy, but its ...
Yu-Han Liu, Li-Bin Zheng, Cheng-Cheng Zhang, Ping-Ping Wang, Yixin Zhang, Peiyue Peng, Xinyu Zhang, Qing-Feng Ma, Xun Li, Lu Liu   +9 more
semanticscholar   +1 more source

Stent Retriever AssIsted Lysis Technique with Tirofiban: A Potential Bailout Alternative to Angioplasty and Stenting

American Journal of Neuroradiology
BACKGROUND AND PURPOSE: Angioplasty and stent placement have been described as a bailout technique in individuals with failed thrombectomy. We aimed to investigate Stent retriever AssIsted Lysis (SAIL) with tirofiban before angioplasty and stent ...
M. Rodrigo-Gisbert, Matúš Hoferica, Á. García-Tornel, M. Requena, M. Rubiera, M. De Dios Lascuevas, M. Olivé-Gadea, Francesco Diana, F. Rizzo, M. Muchada, T. Carmona, N. Rodriguez-Villatoro, D. Rodriguez-luna, J. Juega, J. Pagola, D. Hernández, Carlos A. Molina, A. Tomasello, C. Cognard, M. Ribó   +19 more
semanticscholar   +1 more source

Intravenous thrombolysis plus tirofiban versus tirofiban alone in Caucasian patients with acute anterior choroidal or paramedian pontine infarction

Brain Circulation
BACKGROUND: Tirofiban has been shown to be superior to aspirin in achieving functional independence at 3 months for acute ischemic stroke of atheromatous or microatheromatous origin.
Moussa Toudou-Daouda, Roger-Venant Yatwa-Zaniwe, N. Aminou-Tassiou, M. Baby, D. Soumah, Tony Altarcha, M. Aghasaryan, Olga Lainé, N. Chausson, D. Smadja   +9 more
semanticscholar   +1 more source

Tirofiban counteracts endothelial cell apoptosis through the VEGF/VEGFR2/pAkt axis

, 2016
Tirofiban is used in the treatment of patients with acute coronary syndrome submitted to percutaneous coronary intervention (PCI). We have, previously, shown that tirofiban stimulates VEGF expression and promotes proliferation of endothelial cells.
Biondi-Zoccai, Giuseppe, Ferraro, Paolo, Biondi Zoccai, Giuseppe, Corcione, Nicola, D'ANGELILLO, ANNA, Giordano, Arturo, Avellino, Raffaella, Messina, Stefano, ROMANO, MARIA FIAMMETTA, ROMANO, SIMONA   +9 more
core   +1 more source

Tirofiban provides 'platelet anesthesia' during cardiopulmonary bypass in baboons

, 1997
Objective: Tirofiban (Aggrastat) is a reversible, nonpeptide inhibitor of platelet glycoprotein II/IIIa receptors. We tested the hypothesis that tirofiban preserves platelet number and function and shortens postoperative bleeding times in baboons after ...
Niewiarowski, S., Harry L. Anderson, Cezary Marcinkiewicz, Gorman III, J. H., Yuji Hiramatsu, Gikakis, N., Nicolas Gikakis, Joseph H. Gorman, Anderson III, H. L., Kirklin, J. K., L.Henry Edmunds, Bidstrup, B. P., Robert J. Gould, Marcinkiewicz, C., Edmunds L.H., Jr, Gould, R. J., Hiramatsu, Y., Stefan Niewiarowski, Verrier, E. D.   +18 more
core   +1 more source

Effect of intravenous tirofiban on the radiologic classification of intracranial hemorrhage after endovascular treatment in acute anterior circulation occlusive stroke: results from the RESCUE BT trial

Journal of Stroke and Cerebrovascular Diseases
Purposes: Intracranial hemorrhage (ICH) is a serious complication after endovascular treatment (EVT) for large vessel occlusive stroke. Using data from RESCUE BT, we aimed to investigate the relationship between intravenous tirofiban preceding EVT and ...
Feng Peng, MD, Chunzhen Zhang, MD, Shuiwen Li, MD, Wenjie Zi, PhD, Changwei Guo, PhD, Zhouzhou Peng, PhD, Yun Xiao, MD, Shitao Fan, PhD, Fengli Li, PhD   +8 more
doaj   +1 more source

Safety Profile of Intra-Arterial Tirofiban as a Rescue Therapy during Mechanical Thrombectomy in Acute Ischemic Stroke

Journal of Clinical Interventional Radiology ISVIR
Objective  This article studies the safety profile and role of intra-arterial (IA) tirofiban as a rescue therapy in acute ischemic stroke (AIS) patients undergoing mechanical thrombectomy.
K. M. Athiyappan, M. Cherian, Pankaj Mehta, S. Poyyamoli, N. H. Reddy, Anupchakravarthy Jayaraj, S. A. Palathingal   +6 more
semanticscholar   +1 more source

Effect of Intravenous Tirofiban Versus Placebo on First‐Pass Successful Reperfusion in Endovascular Stroke Thrombectomy: Insights From the RESCUE BT Randomized Clinical Trial

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease
Background First‐pass successful reperfusion (FPSR), defined as a successful/complete reperfusion achieved after a single thrombectomy pass, is predictive of favorable outcome in patients with acute ischemic stroke with large‐vessel occlusion.
Jun-Jie Yuan, Han-Ming Ge, Zhaojun Tao, Huijie An, Qin Han, J. Saver, Thanh N. Nguyen, Simin Zhou, An Mao, Yue-Lu Wu, Raul G. Nogueira, Ya-Xuan Sun, Shun-Fu Jiang, Li-Ping Wei, Xin-Min Fu, Yong-Jie Bai, Shun-Yu Yang, Wei Hu, Gu-Ling Zhang, Chen-Hui Pan, Shuai Zhang, Lin Qiao, Qiong Chen, Hong-Fei Sang, Zhongming Qiu, Fengfu Wu, Ming-Ze Chang, Zhong-Fan Ruan   +27 more
semanticscholar   +1 more source

Safety and efficacy of tirofiban treatment in the endovascular treatment of patients with acute ischaemic stroke - A meta-analysis.

Clinical neurology and neurosurgery (Dutch-Flemish ed. Print)
OBJECT The use of endovascular therapy (EVT) has become a widespread strategy for the clinical management of acute ischemic stroke (AIS). However, the combination of arterial injection of tirofiban with EVT for AIS continues to be a subject of ...
Wei Li, Kangmeng Wang, Chao-Kun Zeng, KaiLai Huang, Yusi Fu, Zhen-Qiang Zhao   +5 more
semanticscholar   +1 more source