Results 11 to 20 of about 12,790 (219)

Tirofiban for Preventing Early Neurological Deterioration in Acute Ischemic Stroke Within 48 Hours of Onset: Evidence From a Dual-Method Analysis Using Propensity Score Matching and Multivariable Regression. [PDF]

CNS Neurosci Ther
Previous studies have shown that tirofiban may reduce the risk of early neurological deterioration within 24 h after symptom onset in patients with acute ischemic stroke (AIS). However, evidence on its efficacy beyond this time window is limited. This study suggests that tirofiban may still confer potential therapeutic benefits in AIS patients without ...
Wen Q, Zhao Y, Deng Y, Guan S, Zhang S, Zhou J, Zhu P, Fan X, Li J, Chen Y, Cai G, Huang Y, Zheng S, Meng H.   +13 more
europepmc   +2 more sources

Tirofiban on First-Pass Recanalization in Acute Stroke Endovascular Thrombectomy: The OPTIMISTIC Randomized Clinical Trial. [PDF]

JAMA Netw Open
Lin L, Liu F, Yi T, Zhu Y, Yang J, Zhao Y, Wang F, Xiang G, Chen C, Xiao Y, Shen H, Xu L, Long Y, Zhang Y, Huang Z, Chen C, Churilov L, Parsons MW, Chen W, Li G, OPTIMISTIC Investigators.   +20 more
europepmc   +2 more sources

Efficacy and safety of tirofiban injection with intracranial stenting in early reocclusion due to intracranial atherosclerosis

Interdisciplinary Neurosurgery, 2022
Objective: We aimed to develop an optimal protocol for failed mechanical thrombectomy (MT) in cases of emergent large vessel occlusion (ELVO) with intracranial atherosclerosis (ICAS).
Yun Ho Noh, Ji Young Lee, Seok Mann Yoon, Yu Jin Ha, Jaewoo Chung, Jung Ho Ko, Dong Seong Shin, Jae-Min Ahn, Hyuk Jin Oh, Jai-Joon Shim, Man Ryul Lee, Jae Sang Oh   +11 more
doaj   +1 more source

Tirofiban interferes with antibody-mediated transfusion-related acute lung injury by inhibiting platelet-neutrophil binding

Zhongguo shuxue zazhi, 2022
Objective To explore the feasibility of tirofiban, a platelet surface glycoprotein (GP)Ⅱb/Ⅲa receptor antagonist intervene in transfusion-related acute lung injury (TRALI), by inhibiting platelet activation and by preventing platelet and neutrophil ...
Xin YUAN, Yunhong YU, Congchao QIAO, Pan SUN, Na SU, Peng JIANG, Fangzhao LIN   +6 more
doaj   +1 more source

Comparison of the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris in long term follow‐up

Kaohsiung Journal of Medical Sciences, 2021
To investigate the effect of ticagrelor combined with tirofiban versus clopidogrel combined with tirofiban on inflammation response and prognosis of patients with unstable angina pectoris (UA).
Li Deng, Hai‐Zhen Jia, Mao‐Chun Li, Wei Zhu   +3 more
doaj   +1 more source

Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study

BMC Neurology, 2020
Background Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT).
Yong-Won Kim, Sung-Il Sohn, Joonsang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Dong-Hun Kang, Yong-Sun Kim, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Yang-Ha Hwang, Jin Soo Lee   +11 more
doaj   +1 more source

Safety and Efficacy of Low-Dose Tirofiban Combined With Intravenous Thrombolysis and Mechanical Thrombectomy in Acute Ischemic Stroke: A Matched-Control Analysis From a Nationwide Registry

Frontiers in Neurology, 2021
Purpose: Tirofiban administration to acute ischemic stroke patients undergoing mechanical thrombectomy with preceding intravenous thrombolysis remains controversial.
Gaoting Ma, Shuo Li, Baixue Jia, Dapeng Mo, Ning Ma, Feng Gao, Xiaochuan Huo, Gang Luo, Anxin Wang, Yuesong Pan, Ligang Song, Xuan Sun, Xuelei Zhang, Liqiang Gui, Cunfeng Song, Ya Peng, Jin Wu, Shijun Zhao, Junfeng Zhao, Zhiming Zhou, Zhongrong Miao   +20 more
doaj   +1 more source

Can Tirofiban Improve the Outcome of Patients With Acute Ischemic Stroke: A Propensity Score Matching Analysis

Frontiers in Neurology, 2021
Objective: To evaluate the efficacy and safety of tirofiban for patients with acute ischemic stroke (AIS), especially posterior circulation stroke (PCS).Methods: We enrolled consecutive patients with AIS who suffered large artery occlusion (LAO) and ...
Lingxin Cai, Xiaobo Yu, Jun Yu, Jing Xu, Liang Xu, Chenhan Ling, Min Lou, Cheng Yu, Cong Qian   +8 more
doaj   +1 more source

Blood Pressure Variability and 90-Day Functional Outcome in Branch Atheromatous Disease-Related Stroke: A Multicenter Prospective Study. [PDF]

J Clin Hypertens (Greenwich)
ABSTRACT Branch atheromatous disease (BAD)‐related stroke shows distinct prognostic features from other stroke subtypes, with modifiable prognostic factors remaining inconclusive. The present research investigated the association between systolic blood pressure variability (BPV) and 90‐day functional outcomes of BAD‐related stroke.
Zhou Y, Li S, Hu H, Zhu YC, Peng B, Zhou L, Ni J, BAD‐study investigators.   +7 more
europepmc   +2 more sources

Safety and efficacy of tirofiban after intravenous thrombolysis with urokinase in patients with acute ischemic stroke. [PDF]

Front Neurol
Qu D, Liu H, Wei Z, Cheng Y, Fei Y, Xu J, Lv X, Li W.   +7 more
europepmc   +3 more sources