Results 11 to 20 of about 6,300 (191)
Therapeutic efficiency of tirofiban in acute coronary syndromes [PDF]
The Lancet, 2000 John R. Burnett +4 more
+9 more sources
Effects of tirofiban on haemostatic activation in vitro [PDF]
British Journal of Anaesthesia, 2004 Thrombin plays a critical role in normal haemostasis and pathological thrombosis. Heparin has long been a mainstay choice of antithrombotic regimen in cardiac patients, but persistent thrombin generation seems to occur during heparin therapy. Because platelets are integral to primary haemostasis and clot formation, we evaluated the use of tirofiban ...
Kenichi A. Tanaka +5 more
openalex +4 more sources
Tirofiban-induced thrombocytopenia
Annals of Medicine, 2023 Tirofiban is a small non-peptide ligand-mimetic Glycoprotein (GP) IIb/IIIa inhibitor which can reversibly bind to the arginine-glycine-aspartic acid (RGD) recognition site of GP IIb/IIIa to prevent platelet aggregation. It reduces the incidence of thrombotic cardiovascular events in patients with non-ST-segment elevation acute coronary syndrome (NSTE ...
Jun Wang, Dongna Zou
openaire +3 more sources
Tirofiban-Induced Profound Thrombocytopenia: A Case Report. [PDF]
CureusPlatelet glycoprotein IIB/IIIA antagonists are potent inhibitors of platelet aggregation. Although the incidence of thrombocytopenia following their administration is relatively low, it can sometimes lead to fatal consequences. We report a case of a 57-year-old gentleman presenting with non-ST elevation myocardial infarction complicated with tirofiban ...
Al Achkar Z +3 more
europepmc +3 more sources
Pakistan Journal of Health Sciences, 2023 Major Adverse Cardiovascular Events (MACE) and and Cerebrovascular Accidents (CVA) have become primary areas of interest due to the ongoing focal research in cardiovascular diseases. Objective: To assess the frequency of major adverse cardiac events and cerebrovascular accidents for intracoronary tirofiban and intravenous tirofiban. Methods: It was
Syed Husnain Raza Bukhari +5 more
openaire +1 more source
Platelets, 2022 We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry.
Martina Aguiar Bucsai +4 more
doaj +1 more source
Journal of Neurorestoratology, 2022 ObjectiveTo investigate the effectiveness and safety of tirofiban in patients with acute ischemic stroke (AIS) without large-vessel occlusions and not receiving intravenous thrombolysis.MethodsOverall, 267 cases were included in the study (134 cases in ...
Yongpeng Yu +4 more
doaj +1 more source
Hemorragia alveolar asociada con tirofiban
Revista Repertorio de Medicina y Cirugía, 2023 Case: we present a patient with alveolar hemorrhage associated with tirofiban, whose diagnosis was delayed because the initial signs, which were misinterpreted as pneumonia, were unrecognized. Discussion and conclusions: an early and accurate diagnosis is essential to guide the appropriate management of any type of bleeding complication in a patient ...
Alexander Aguilar Arias +4 more
openaire +2 more sources
Safety and efficacy of low-dose and long-course tirofiban in large hemispheric infarction
Frontiers in Neurology, 2022 BackgroundThe clinical efficacy and safety of tirofiban in the treatment of large hemispheric infarction (LHI) remain controversial.MethodsThis study prospectively enrolled patients with acute LHI who were admitted to Putuo Hospital affiliated with ...
Yinqin Hu +6 more
doaj +1 more source
BMC Neurology, 2022 Background Even undergoing mechanical thrombectomy (MT), patients with acute vertebrobasilar artery occlusion (AVBAO) still have a high rate of mortality.
Xiding Pan +6 more
doaj +1 more source