Results 11 to 20 of about 6,111 (204)

Efficacy and safety of tirofiban in acute ischemic stroke patients with ideal reperfusion: A cohort study of LAA and CE subgroups [PDF]

European Journal of Neurology, Volume 32, Issue 1, January 2025.
Abstract Background and Objectives Despite achieving ideal reperfusion (eTICI = 3) through endovascular treatment (EVT), some acute ischemic stroke (AIS) patients still experience poor outcomes. This study aims to evaluate the efficacy and safety of tirofiban in AIS patients with ideal reperfusion, focusing on its effects in large artery ...
Chengsong Yue, Xiang Liu, Changwei Guo, Lilan Wang, Wenlong Zhao, Wenzhe Sun, Jiaxing Song, Jie Yang, Linyu Li, Nizhen Yu, Shihai Yang, Xiaolei Shi, Jiacheng Huang, Weiling Kong, Zhenqiang Li, Shunyu Yang, Shuang Yang, Wenjie Zi, Yi Lin, Fengli Li   +19 more
wiley   +2 more sources

Tirofiban Benefits the Outcome of Stroke Patients With Large Artery Atherosclerosis Achieving Full Reperfusion and High NIHSS Scores [PDF]

Eur J Neurol
European Journal of Neurology, Volume 32, Issue 2, February 2025.
Adrià Arboix, Olga Parra
wiley   +2 more sources

Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model [PDF]

Nature Communications
Venous thrombosis (VT) is a common vascular disease associated with reduced survival and a high recurrence rate. VT is initiated by the accumulation of platelets and neutrophils at sites of endothelial cell activation. A role for platelet αIIbβ3 in VT is
Brian D. Adair, Conroy O. Field, José L. Alonso, Jian-Ping Xiong, Shi-Xian Deng, Hyun Sook Ahn, Eivgeni Mashin, Clary B. Clish, Johannes van Agthoven, Mark Yeager, Youzhong Guo, David A. Tess, Donald W. Landry, Mortimer Poncz, M. Amin Arnaout   +14 more
doaj   +2 more sources

Preoperative and intraoperative tirofiban during endovascular thrombectomy in large vessel occlusion stroke due to large artery atherosclerosis [PDF]

European Journal of Neurology, Volume 31, Issue 10, October 2024.
Abstract Background and purpose The aim of this study is to investigate the efficacy and safety of preoperative versus intraoperative tirofiban in patients with large vessel occlusion (LVO) due to large artery atherosclerosis (LAA). Methods This is a retrospective multicenter cohort study based on the RESCUE‐RE (Registration Study for Critical Care of ...
Zhiqiang Sun, Shuhan Huang, Wei Li, Yi Yang, Ya Wu, Xue Ma, Ximing Nie, Wangsheng Jin, Chengchun Liu, Xiaoshu Li, Yaning Xu, Jun Dong, Yisi Liao, Binlu Sun, Wenjun Han, Qing Zhao, Huaqiao Chi, Yanjiang Wang, Liping Liu, Meng Zhang   +19 more
wiley   +2 more sources

The impact of intraarterial, intravenous, and combined tirofiban on endovascular treatment for acute intracranial atherosclerotic occlusion [PDF]

Frontiers in Neurology
Background and purposeAdjunctive tirofiban administration in patients undergoing endovascular treatment (EVT) for acute large vessel occlusion (LVO) has been investigated in several studies. However, the findings are conflict. This study aimed to compare
Zhiping Bu, Dapeng Sun, Gaoting Ma, Baixue Jia, Xu Tong, Xiaochuan Huo, Anxin Wang, Ning Ma, Feng Gao, Dapeng Mo, Ligang Song, Xuan Sun, Yiming Deng, Xiaoqing Li, Bo Wang, Gang Luo, Deguo Su, Zhongrong Miao   +17 more
doaj   +2 more sources

Tirofiban combined with Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY): protocol for a multicentre, randomised controlled trial [PDF]

Stroke and Vascular Neurology
Background Perforating artery territorial infarction (PAI) caused by branch atheromatous disease (BAD) is prone to recurrence and early progression without an effective and well-documented antiplatelet treatment regimen.
Liping Liu, Yongjun Wang, Yilong Wang, Xingquan Zhao, Xiaoling Liao, Weiqi Chen, Yuesong Pan, Hui Qu, Shuo Feng, Yicong Wang   +9 more
doaj   +2 more sources

Cost-effectiveness of tirofiban for acute ischemic stroke without large or medium-sized vessel occlusion: A Markov modelling analysis from the Chinese and United States perspectives. [PDF]

PLoS ONE
BackgroundThe RESCUE BT2 trial recently showcased the efficacy of tirofiban in treating acute ischemic stroke (AIS) without large or medium-sized vessel occlusion.
Li Wang, Yuhong Zeng, Limei Zhou, Ping Xu, Xianbin Guo, Yu Xie, Junxiu Cai, Min Pan, Jie Tang, Qingtao Gong, Rong Su, Yan Liu, Yake Lou   +12 more
doaj   +2 more sources

Number of Retrieval Attempts and the Association of Intravenous Tirofiban with Symptomatic Intracranial Hemorrhage in Patients with Successful Endovascular Therapy: Results of the RESCUE BT Trial [PDF]

Clinical Interventions in Aging
Xiangxiang Peng,1,* Changwei Guo,2,* Jie Yang,2 Shitao Fan,2 Xu Xu,2 Jinfu Ma,2 Zhixi Wang,2 Shihai Yang,2 Wenjie Zi,2 Xianjun Huang,1 Hongjun Wang3 1Department of Neurology, Yijishan Hospital of Wannan Medical College, Wuhu, Anhui Province ...
Peng X, Guo C, Yang J, Fan S, Xu X, Ma J, Wang Z, Yang S, Zi W, Huang X, Wang H   +10 more
doaj   +2 more sources

The safety and efficacy of intra-arterial low-dose tirofiban administration during endovascular therapy in patients with large ischemic core volume [PDF]

Scientific Reports
This study aimed to evaluate the safety and efficacy of intra-arterial (IA) administration of low- dose tirofiban during endovascular therapy in patients with large ischemic core volumes on initial brain CT. Patients were divided into two groups based on
Kwang-Chun Cho, Nak-Hoon Son, So Hyeon Gwon, Jin Wook Choi, Woo Sang Jung   +4 more
doaj   +2 more sources

Tirofiban potentiates agonist-induced platelet activation and degranulation, despite effectively inhibiting aggregation

Platelets, 2022
We aimed to investigate the effects of integrin αIIbβ3 inhibitor tirofiban on hallmarks of platelet activation, degranulation, and aggregation during its use to analyze activated but non-complexed platelets via flow cytometry.
Martina Aguiar Bucsai, Christian Idel, Barbara Wollenberg, Christine Mannhalter, Admar Verschoor   +4 more
doaj   +1 more source