Results 31 to 40 of about 12,125 (226)
BMC Neurology, 2022 Background Even undergoing mechanical thrombectomy (MT), patients with acute vertebrobasilar artery occlusion (AVBAO) still have a high rate of mortality.
Xiding Pan +6 more
doaj +1 more source
Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells.
, 2014 Tirofiban is a fibrinogen receptor antagonist, generated using the tripeptide Arg-Gly-Asp (RGD) as a template. RGD activates integrin receptors and integrin-mediated signals are necessary for normal cells to promote survival and stimulate cell cycle ...
D'Arrigo P +17 more
core +2 more sources
Chronic Diseases and Translational Medicine, 2015 Objective: To evaluate the efficacy and short term prognosis of Tirofiban in different treatment duration in patients with acute ST segment elevation myocardial infarction (STEMI) and percutaneous coronary intervention (PCI) combined with intracoronary ...
Zhen-Guo Ji +6 more
doaj +1 more source
Biochemistry Research International, 2020 Introduction. Limited comparative studies have reported the safety and efficacy of tirofiban in acute ischemic stroke (AIS) patients after mechanical thrombectomy (MT).
Lili Zhao +15 more
doaj +1 more source
Safety and efficacy of low-dose and long-course tirofiban in large hemispheric infarction
Frontiers in Neurology, 2022 BackgroundThe clinical efficacy and safety of tirofiban in the treatment of large hemispheric infarction (LHI) remain controversial.MethodsThis study prospectively enrolled patients with acute LHI who were admitted to Putuo Hospital affiliated with ...
Yinqin Hu +6 more
doaj +1 more source
Long-Term Outcomes of Local Tirofiban Infusion for Intracranial Atherosclerosis-Related Occlusion
Brain Sciences, 2022 Local tirofiban infusion has been reported as a rescue strategy for intracranial atherosclerotic stenosis (ICAS)-related stroke. However, the long-term outcomes of local tirofiban infusion during endovascular reperfusion therapy (ERT) for ICAS-related ...
Woochan Choi +2 more
doaj +1 more source
Tirofiban on First-Pass Recanalization in Acute Stroke Endovascular Thrombectomy
JAMA Network OpenKey Points Question Does intravenous tirofiban initiated before thrombectomy increase the likelihood of first-pass recanalization without increasing the risk of symptomatic intracranial hemorrhage in patients who have had an acute ischemic stroke ...
Longting Lin +59 more
semanticscholar +1 more source
Acute Serious Thrombocytopenia Associated with Intracoronary Tirofiban Use for Primary Angioplasty [PDF]
, 2014 Tirofiban, a specific glycoprotein IIb/IIIa inhibitor, may cause extensive thrombocytopenia with an incidence of 0.2% to 0.5%. We report the case of a 50-year-old man who developed thrombocytopenia after tirofiban use (both intracoronary and peripheral ...
Atay, M.H. +14 more
core +2 more sources
Angewandte Chemie, Volume 138, Issue 40, 28 September 2026.Peptide‐to‐Small Molecule Paradigm: Peptidomimetics have evolved from simple mimicry toward drug‐like scaffolds supported by increasing clinical successes. This Perspective highlights the geometric design principles—linear repetition, convergent fusion, and cyclization—defining the next‐generation peptidomimetic architectures capable of targeting ...
Jesang Lee +5 more
wiley +2 more sources
DrugsTirofiban is a selective inhibitor of the glycoprotein IIb/IIIa receptor that reversibly prevents platelet aggregation and clot formation—processes central to the development and progression of ischemic stroke.
Yu-Ye Jiang +3 more
semanticscholar +1 more source