Results 41 to 50 of about 7,611 (182)

Sicherheit von Tirofiban beim akuten ischämischen Schlaganfall im klinischen Alltag [PDF]

, 2009
Die vorliegende Arbeit untersuchte retrospektiv die Sicherheit von Tirofiban in der Behandlung des akuten ischämischen Schlaganfalls in Monotherapie oder in Kombination mit verschiedenen Methoden der Gefäßrekanalisation.
Mädl, Jennifer
core   +1 more source

Incidence of Periprocedural Myocardial Injury and Infarction After Intravascular Lithotripsy for Calcified Coronary Artery Stenosis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Intravascular lithotripsy (IVL) has emerged as an effective technique for modifying heavily calcified coronary plaques, facilitating optimal stent expansion while minimizing procedural complications. However, data on periprocedural myocardial injury (PMI) and infarction (PPMI) following IVL remain scarce.
Gwaenaelle Aellen, Dorian Garin, Yannick Faucherre, Serban Puricel, Mario Togni, Stéphane Cook   +5 more
wiley   +1 more source

Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres, Cristobalina Mayorga, Elizabeth J. Phillips, Adriana Ariza, Annick Barbaud, Patrizia Bonadonna, Mariana Castells, Gülfem Çelik, Knut Brockow, Lene H. Garvey, Inmaculada Doña, Jean‐Christoph Caubet, Francesca Mori, Jason Trubiano, Giorgia Marta, Antonino Romano, Ingrid Terreehorst, Asli Gelincik, Philip H. Li, Vito Sabato   +19 more
wiley   +1 more source

Guideline for the Comprehensive Perioperative Management of Older Patients With Lung Cancer (2025)

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT With the accelerating population aging, the number of older adult patients with lung cancer continues to increase. These patients often present with multiple chronic diseases and geriatric syndromes, resulting in more complex perioperative management and significantly increased surgical risks.
Daiping Li, Rui Liang, Birong Dong, Lunxu Liu, Ning Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +6 more
wiley   +1 more source

Tirofiban Preserves Endothelial Junctions and Decreases Endothelin-1

, 2008
It has been verified that glycoprotein IIb/IIIa inhibitor tirofiban can attenuate myocardial no-reflow. Myocardial no-reflow has been associated with alterations in endothelial junctions.
Yue-Jin YANG, Run-Lin GAO, Ya-Xin LIU, Mei ZHAI, Yu-Hua SUN, Wei-Dong PEI, Jing-Lin ZHAO   +6 more
core   +1 more source

Platelet integrin αIIbβ3 plays a key role in a venous thrombogenesis mouse model

Nature Communications
Venous thrombosis (VT) is a common vascular disease associated with reduced survival and a high recurrence rate. VT is initiated by the accumulation of platelets and neutrophils at sites of endothelial cell activation. A role for platelet αIIbβ3 in VT is
Brian D. Adair, Conroy O. Field, José L. Alonso, Jian-Ping Xiong, Shi-Xian Deng, Hyun Sook Ahn, Eivgeni Mashin, Clary B. Clish, Johannes van Agthoven, Mark Yeager, Youzhong Guo, David A. Tess, Donald W. Landry, Mortimer Poncz, M. Amin Arnaout   +14 more
doaj   +1 more source

Safety and Efficacy of Ultra‐Early Tirofiban Treatment Following Alteplase in Patients With Noncardioembolic Acute Ischemic Stroke

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Secondary platelet activation peaks ≈2 hours after intravenous thrombolysis with alteplase. This study evaluated the safety and efficacy of ultra‐early tirofiban administration and compared different tirofiban regimens following intravenous ...
Qing Zhao, Yi Yang, Wangsheng Jin, Huaqiao Chi, De Yang, Shengli Chen, Chengchun Liu, Ya Wu, Xiaoshu Li, Zhiqiang Sun, Wenjun Han, Zihao Wang, Rongchang Zhao, Yanjiang Wang, Wei Li, Meng Zhang   +15 more
doaj   +1 more source

Association between tirofiban monotherapy and efficacy and safety in acute ischemic stroke

BMC Neurology, 2021
Background Studies have suggested that glycoprotein IIb/IIIa antagonists such as tirofiban are beneficial for patients with acute coronary syndromes.
Chunrong Tao, Yuyou Zhu, Chao Zhang, Jianlong Song, Tianlong Liu, Xiaodong Yuan, Wenwu Luo, Changchun Chen, Dezhi Liu, Yuanyuan Zhu, Jie Liu, Wei Hu   +11 more
doaj   +1 more source

Recombinant Human Thrombopoietin Reduces the Need for Platelet Transfusion in Patients With Chronic Liver Disease and Thrombocytopenia

American Journal of Hematology, Volume 101, Issue 10, Page 2571-2580, October 2026.
ABSTRACT Chronic liver disease (CLD)‐related thrombocytopenia can limit the feasibility of invasive procedures. Recombinant human thrombopoietin (rhTPO) has demonstrated a favorable safety profile without hepatotoxicity. We evaluated the efficacy and safety of rhTPO in patients with CLD‐related thrombocytopenia who were undergoing elective invasive ...
Yifan Han, Ning Lin, Jinghang Xu, Sikui Wang, Jinglan Jin, Jia Shang, Yongning Xin, Youwen Tan, Dazhi Zhang, Jinlin Hou, Ping An, Wen Xie, Yujuan Guan, Qingfang Xiong, Hong Wu, Huiguo Ding, Yu Chen, Rongkuan Li, Zhili Wen, Mingqin Lu, Jinhui Yang, Zhongyin Zhou, Yongjian Zhou, Zujiang Yu, Kecan Lin, Wei Wang, Yan Huang, Yuemin Nan, Xinhua Luo, Rongshu Shi, Yi Kang, Tao Han, Shiyan Chen, Kai Wang, Yunfeng Shan, Jiaping Li, Pingguo Liu, Zheng Lu, Jun Chen, Zhen Liu, Liaoyun Zhang, Li Yang, Jifang Sheng, Zhan Zeng, Yanyan Yu, Xiaoyuan Xu   +45 more
wiley   +1 more source

Mechanical Thrombus Aspiration for a Young STEMI Patient With Plaque Erosion: Time for a Stent‐Free Approach?

Catheterization and Cardiovascular Interventions, Volume 108, Issue 3, Page 833-839, September 1, 2026.
ABSTRACT A 34‐year‐old man with no cardiovascular history presented with anterior ST‐elevation myocardial infarction and a large thrombotic occlusion of the mid left anterior descending artery. Following potent antithrombotic therapy and mechanical thrombus aspiration, angiography revealed vessel patency without residual significant stenosis, allowing ...
Domenico Simone Castiello, Francesco Greco, Antonio Curcio, Alberto Polimeni   +3 more
wiley   +1 more source