Results 51 to 60 of about 6,226 (154)

Tirofiban combined with Aspirin in the Treatment of Acute Penetrating Artery Territory Infarction (STRATEGY): protocol for a multicentre, randomised controlled trial

Stroke and Vascular Neurology
Background Perforating artery territorial infarction (PAI) caused by branch atheromatous disease (BAD) is prone to recurrence and early progression without an effective and well-documented antiplatelet treatment regimen.
Liping Liu, Yongjun Wang, Yilong Wang, Xingquan Zhao, Xiaoling Liao, Weiqi Chen, Yuesong Pan, Hui Qu, Shuo Feng, Yicong Wang   +9 more
doaj   +1 more source

Identification of Key Genes and Pathways Associated With Gender Differences in Pulmonary Arterial Hypertension Based on Bioinformatic Approaches

BioMed Research International, Volume 2026, Issue 1, 2026.
Pulmonary arterial hypertension (PAH) is a complex disease with multiple contributing factors. Epidemiological data showed that women are more susceptible to PAH, but they tend to have better right ventricular (RV) function and prognosis compared to men. The mechanisms behind these gender differences are not well understood.
Mohammad Panahi, Reyhaneh Kalhor, Mohammad-Hossein Mokhtarian, Fatemeh Javaheri Tehrani, Zinat Shams, Hourieh Kalhor, Hannah Wesley   +6 more
wiley   +1 more source

Radiolabeled tirofiban – a potential radiopharmaceutical for detection of deep venous thrombosis

Drug Design, Development and Therapy, 2016
Marija Darkovska-Serafimovska,1,2 Emilija Janevik-Ivanovska,1 Icko Djorgoski,2 Zorica Arsova-Sarafinovska,1,3 Milka Zdravkovska,1 Trajan Balkanov,4 Nenad Ugresic5 1Department of Pharmacy, Faculty of Medical Sciences, Goce Delcev University, Stip ...
Darkovska-Serafimovska M, Janevik-Ivanovska E, Djorgoski I, Arsova-Sarafinovska Z, Zdravkovska M, Balkanov T, Ugresic N   +6 more
doaj  

Comprehensive Review of Antiplatelet Therapy in Secondary Prevention of Myocardial Infarction: Mechanisms, Clinical Evidence, and Future Directions

Cardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Atherosclerotic cardiovascular disease (ASCVD), particularly myocardial infarction (MI), is the leading cause of mortality and morbidity worldwide. The pathophysiology of MI involves atherosclerotic plaque rupture with thrombus formation, interrupting myocardial blood supply with subsequent myocardial necrosis.
May Thu Kyaw, Arkar Moe, Irfan Ahmad
wiley   +1 more source

SAFETY OF TIROFIBAN FOR PATIENTS WITH ACUTE ISCHEMIC STROKE IN ROUTINE CLINICAL PRACTICE

Российский кардиологический журнал, 2014
Aim. This work aims to study the safety of tirofiban alone and in combination with various treatments in acute ischemic stroke (AIS).Material and methods. 120 AIS patients were included in this study.
Yan-Jun Zhang, Qing Liu, Qin Zhan, Qiong Li   +3 more
doaj   +1 more source

Efficacy and safety of tirofiban as an adjunctive therapy in patients with acute ST-segment elevation myocardial infarction undergoing percutaneous transluminal coronary angioplasty

National Journal of Physiology, Pharmacy and Pharmacology, 2016
Background: The introduction of stents and the use of platelet glycoprotein IIb/IIIa inhibitors, either alone or in combination with reduced-dose fibrinolytic therapy, has allowed percutaneous coronary intervention (PCI) to be performed more safely and ...
Sanjay Sharma, Seema Gupta, Sanjeev Bhat, Zahid Gillani, Dinesh Kumar, Rajesh Kumar   +5 more
doaj   +1 more source

Anticoagulant or Antithrombotic Therapy After Early Neurological Deterioration in Patients With Branch Atheromatous Disease Receiving Dual Antiplatelet Therapy

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Objective We evaluated the effectiveness and safety of adding tirofiban or argatroban after early neurological deterioration (END) in patients with branch atheromatous disease (BAD) receiving dual antiplatelet therapy and compared the outcomes with those of patients who continued dual antiplatelet therapy alone. Methods This retrospective study focused
Xuemin Zhong, Juan Yang, Ronghua Xu, Jian Wang, Nikhat Kaura   +4 more
wiley   +1 more source

Safety of tirofiban and dual antiplatelet therapy in treating intracranial aneurysms

Stroke and Vascular Neurology, 2019
Background Endovascular treatment of intracranial aneurysms usually involves stent-assisted coiling (SAC) and flow diverters. Glycoprotein IIb/IIIa inhibitors such as tirofiban and dual antiplatelet therapy (DAPT) are required to prevent thromboembolic ...
David M Hasan, Santiago Ortega-Gutierrez, Edgar A Samaniego, Pascal Jabbour, Jorge A Roa, Daichi Nakagawa, Mario Zanaty, Emilee Gibson   +7 more
doaj   +1 more source

Association of LDL‐C With Angiographic Thrombus Burden in Patients With ST‐Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Journal of Interventional Cardiology, Volume 2026, Issue 1, 2026.
Background High thrombus burden (HTB) during primary percutaneous coronary intervention (PCI) for ST‐segment elevation myocardial infarction (STEMI) is associated with adverse outcomes. Low‐density lipoprotein cholesterol (LDL‐C) is a key driver of atherosclerosis, but its direct role in acute thrombus formation remains unclear.
Tuo Han, Hytham H. Al-Samawi, Jing Xiao, Xiyu Gao, Gen Liu, Di Bai, Chunyan Zhang, Wei Jiang, Yan Zhang, Irfan Ahmad   +9 more
wiley   +1 more source

Adjunct tirofiban treatment after successful endovascular thrombectomy recanalisation in acute anterior circulation ischaemic stroke (ATTRACTION): protocol of a multicentre, prospective, double-blinded, randomised trial

Stroke and Vascular Neurology
Background Successful recanalisation without functional independence is a frequent phenomenon following endovascular thrombectomy (EVT) for large vessel occlusion (LVO) stroke.Aim To demonstrate the safety and efficacy of adjunct tirofiban therapy after ...
Wei Wang, Yi Zhang, Hao Huang, Zhouping Tang, Xiang Luo, Guo Li, Yiming Luo, Ying Yu, Gang Deng, Chen-Chen Liu, Sha-Bei Xu, Yi Xie, Qianqian Kong, Yi-Hui Wang, Dong-Hui Ao, Lingning Lan   +15 more
doaj   +1 more source