Results 51 to 60 of about 7,611 (182)

Efeito protetor de antagonista das gliproteínas IIb/IIa nas alterações hepáticas e pulmonares secundárias à isquemia e reperfusão do fígado em ratos Protective effects of an inhibitor of glycoprotein IIb/IIIa in the hepatic and pulmonary disturbances secondary to ischemia and reperfusion injury of rat’s liver

Arquivos de Gastroenterologia, 2007
RACIONAL: A lesão de isquemia e reperfusão hepática é um evento comum e responsável por considerável morbidade e mortalidade. OBJETIVO: Avaliar efeitos de inibidor da glicoproteína IIb/IIIa, cloridrato de tirofiban, nas alterações hepáticas e pulmonares ...
Leonardo F. Canedo, Marcel Autran C. Machado, Ana M. M. Coelho, Sandra N. Sampietre, Telesforo Bachella, Marcel C. C. Machado   +5 more
doaj   +1 more source

Safety and Efficacy of Tirofiban During Intravenous Thrombolysis Bridging to Mechanical Thrombectomy for Acute Ischemic Stroke Patients: A Meta-Analysis

Frontiers in Neurology, 2022
IntroductionThe safety and efficacy of tirofiban in intravenous thrombolysis (IVT) bridging to mechanical thrombectomy in patients with acute ischemic stroke (AIS) is unknown.
Wei Li, Wei Li, Wei Li, Guohui Lin, Zaixing Xiao, Zaixing Xiao, Yichuan Zhang, Yichuan Zhang, Bin Li, Bin Li, Yu Zhou, Yu Zhou, Erqing Chai, Erqing Chai   +13 more
doaj   +1 more source

Low-dose intravenous tirofiban infusion after endovascular recanalization for non-acute middle cerebral artery occlusion

Heliyon, 2022
Background and purpose: Endovascular recanalization for patients with symptomatic non-acute middle cerebral artery occlusion still remines challenging. Postoperative treatment is still controversial.
Zhang Xi, Chen Zhibin, Luo Yun, Duan Guangxin, Zhang He, Li Jingwei, Xu Yun   +6 more
doaj   +1 more source

Tirofiban induces VEGF production and stimulates migration and proliferation of endothelial cells.

, 2014
Tirofiban is a fibrinogen receptor antagonist, generated using the tripeptide Arg-Gly-Asp (RGD) as a template. RGD activates integrin receptors and integrin-mediated signals are necessary for normal cells to promote survival and stimulate cell cycle ...
D'Arrigo P, Pepino P, Giordano A, D'ANGELILLO, ANNA, Messina S, Ferraro P, Corcione N, ROMANO, MARIA FIAMMETTA, BISOGNI, RITA, Polimeno M, ROMANO, SIMONA   +10 more
core   +2 more sources

Venom‐Derived Bioactive Peptides: From Toxins to Therapeutics

Advanced Therapeutics, Volume 9, Issue 8, August 2026.
Venomics → Target Identification → Peptide Optimization → Therapeutic Translation Bioactive venom peptides targeting ion channels, enzymes, and receptors drive the development of next‐generation precision therapeutics. ABSTRACT Venoms are complex biochemical mixtures composed of diverse bioactive components, including proteins, enzymes, small molecules,
Eldho Sabu, Othman Al Musaimi
wiley   +1 more source

Safety and Efficacy of Tirofiban During Mechanical Thrombectomy for Stroke Patients with Preceding Intravenous Thrombolysis

Clinical Interventions in Aging, 2020
Xiaochuan Huo,1,2,* Ming Yang,1,2,* Ning Ma,1,2 Feng Gao,1,2 Dapeng Mo,1,2 Xiaoqing Li,1,2 Anxin Wang,2,3 Yongjun Wang,2,3 Zhongrong Miao1,2 1Department of Interventional Neuroradiology, Beijing Tiantan Hospital, Capital Medical University, Beijing ...
Huo X, Yang M, Ma N, Gao F, Mo D, Li X, Wang A, Wang Y, Miao Z   +8 more
doaj  

Efficacy and Safety of Intracoronary versus Intravenous Administration of Tirofiban during Percutaneous Coronary Intervention for Acute Coronary Syndrome: A Meta-Analysis of Randomized Controlled Trials. [PDF]

PLoS ONE, 2015
Percutaneous coronary intervention (PCI) is known as the most effective treatment for acute coronary syndrome (ACS). However, without proper therapy and patient management, stent thrombosis after PCI may lead to another myocardial infarction. In addition
Xiuying Tang, Runjun Li, Quanmin Jing, Yingfeng Liu, Peng Liu   +4 more
doaj   +1 more source

There is no difference in safety and efficacy mechanical thrombectomy alone or mechanical thrombectomy with tirofiban for patients undergoing treatment of large vessel occlusion and underlying intracranial atherosclerosis

Interdisciplinary Neurosurgery, 2022
Background: Mechanical thrombectomy (MT) is a widely proven method to treat acute ischemic stroke (AIS) during mechanical thrombectomy and acute stenting and angioplasty is a topic discussed till this day regarding safety and efficacy.
Hari Movva, Rani Rabah, Wondwossen Tekle, Laurie Preston, Hari Kotta, Ameer E Hassan   +5 more
doaj   +1 more source

Bridging Therapy Versus Intravenous Thrombolysis Alone in Patients With Medium Vessel Occlusion Stroke: A Single‐Center Cohort Study

Brain and Behavior, Volume 16, Issue 8, August 2026.
ABSTRACT Background To compare the outcomes of bridging therapy versus intravenous thrombolysis (IVT) alone in patients with medium vessel occlusion (MeVO). Methods Consecutive MeVO patients between January 2019 and December 2024 were retrospectively included and classified into IVT alone or bridging therapy groups.
Di Hu, Mo Yang, Zhenghua Gu, Jie Fan, Lizhi Yu, Chengcai Xia, Qingguo Ren   +6 more
wiley   +1 more source

Data_Sheet_1_Can Tirofiban Improve the Outcome of Patients With Acute Ischemic Stroke: A Propensity Score Matching Analysis.docx

, 2021
Objective: To evaluate the efficacy and safety of tirofiban for patients with acute ischemic stroke (AIS), especially posterior circulation stroke (PCS).Methods: We enrolled consecutive patients with AIS who suffered large artery occlusion (LAO) and ...
Liang Xu (102656), Lingxin Cai (11425606), Cheng Yu (797688), Chenhan Ling (4886887), Jun Yu (5904), Jing Xu (15337), Min Lou (332318), Cong Qian (6109403), Xiaobo Yu (327693)   +8 more
core   +1 more source