Results 11 to 20 of about 7,611 (182)

The impact of intraarterial, intravenous, and combined tirofiban on endovascular treatment for acute intracranial atherosclerotic occlusion [PDF]

Frontiers in Neurology
Background and purposeAdjunctive tirofiban administration in patients undergoing endovascular treatment (EVT) for acute large vessel occlusion (LVO) has been investigated in several studies. However, the findings are conflict. This study aimed to compare
Zhiping Bu, Dapeng Sun, Gaoting Ma, Baixue Jia, Xu Tong, Xiaochuan Huo, Anxin Wang, Ning Ma, Feng Gao, Dapeng Mo, Ligang Song, Xuan Sun, Yiming Deng, Xiaoqing Li, Bo Wang, Gang Luo, Deguo Su, Zhongrong Miao   +17 more
doaj   +2 more sources

Adjunct Intraarterial or Intravenous Tirofiban Versus No Tirofiban After Successful Recanalization of Basilar Artery Occlusion Stroke: The BASILAR Registry [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Approximately half of patients who achieve successful reperfusion do not achieve functional independence. The present study sought to investigate the clinical outcomes and safety of intraarterial or intravenous tirofiban as adjunct therapy in ...
Huagang Li, Dongsheng Ju, Zhaojun Tao, Jiayin Wang, Thanh N. Nguyen, Jeffrey L. Saver, Raul G. Nogueira, Chang Liu, Qingwu Yang, Zhongming Qiu, Congguo Yin, Dong Sun, Shudong Liu   +12 more
doaj   +2 more sources

Mechanical Solitaire Thrombectomy with Low-Dose Booster Tirofiban Injection [PDF]

Neurointervention, 2016
PurposeMechanical thrombectomy using a Solitaire stent has been associated with a high recanalization rate and favorable clinical outcome in intra-arterial thrombolysis.
Duck-Ho Goh, Sung-Chul Jin, Hae Woong Jeong, Sam Yeol Ha   +3 more
doaj   +3 more sources

Influence of Tirofiban maintenance duration on patients with acute myocardial infarction treated by percutaneous coronary intervention [PDF]

Chronic Diseases and Translational Medicine, 2015
Objective: To evaluate the efficacy and short term prognosis of Tirofiban in different treatment duration in patients with acute ST segment elevation myocardial infarction (STEMI) and percutaneous coronary intervention (PCI) combined with intracoronary ...
Zhen-Guo Ji, Hong-Bin Liu, Zhi-Hong Liu, Guo-Ping Ma, Li-Qiang Qin, Wei Dong, Li-Ya Wang   +6 more
doaj   +2 more sources

Safety and Efficacy of Tirofiban in Severe Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

Journal of Cardiovascular Development and Disease, 2022
Tirofiban has recently shown encouraging efficacy and safety among acute ischemic stroke (AIS) patients with mechanical thrombectomy (MT). However, the benefits of tirofiban varied among studies depending on the patient’s condition, which was often not ...
Lingxin Cai, Tingting Wang, Aiqing Chen, Chenhan Ling, Jing Xu, Cong Qian, Gao Chen   +6 more
doaj   +2 more sources

Radiolabeled tirofiban – a potential radiopharmaceutical for detection of deep venous thrombosis

Drug Design, Development and Therapy, 2016
Marija Darkovska-Serafimovska,1,2 Emilija Janevik-Ivanovska,1 Icko Djorgoski,2 Zorica Arsova-Sarafinovska,1,3 Milka Zdravkovska,1 Trajan Balkanov,4 Nenad Ugresic5 1Department of Pharmacy, Faculty of Medical Sciences, Goce Delcev University, Stip ...
Darkovska-Serafimovska M, Janevik-Ivanovska E, Djorgoski I, Arsova-Sarafinovska Z, Zdravkovska M, Balkanov T, Ugresic N   +6 more
doaj   +1 more source

Case report: reuse of tirofiban leads to very severe thrombocytopenia [PDF]

Frontiers in Cardiovascular Medicine, 2023
BackgroundTelofiban is a class of small molecule non-peptide tyrosine derivatives containing RGD sequences. It is the only platelet surface glycoprotein (GP) IIb/IIIa receptor antagonist (GPI) currently marketed in China.
Yuqing Li, Jiuchun Qiu, Yi Gao, Guangping Li   +3 more
doaj   +2 more sources

Subtyping treatment response of tirofiban in acute ischemic stroke based on neuroimaging features

Clinical and Translational Science
In a previously published clinical trial, we demonstrated that tirofiban was effective and safe in acute ischemic stroke (AIS) patients who did not undergo early recanalization treatments.
Bin Han, Xu Man, Jian Ding, Yuzhu Li, Xintao Tian, Xuelian Zhu, Jiang Yu, Jinping Sun   +7 more
doaj   +2 more sources

Impact of Preemptive vs. Conventional Tirofiban Administration on the Outcomes in Acute Branch Atheromatous Disease: A Propensity Score-Weighted Cohort Study. [PDF]

CNS Neurosci Ther
In acute branch atheromatous disease stroke, preemptive tirofiban within 72 h significantly raised the 90‐day excellent outcome rate (76.6% vs. 44.6%) and shortened hospitalization without increasing mortality or recurrence. Preemptive administration independently predicted favorable recovery, with enhanced neuroprotection in patients over 65 years ...
Li C, Jin Y, Liu X, Liu Y, Yang W, Wang Y, Ju D.   +6 more
europepmc   +2 more sources

Gene mutations of platelet glycoproteins and response to tirofiban in acute coronary syndrome

São Paulo Medical Journal
CONTEXT AND OBJECTIVES: Glycoprotein inhibitors (abciximab, eptifibatide and tirofiban) are used in patients with unstable angina and non-ST-segment elevation myocardial infarction before percutaneous coronary intervention.
Antonio de Padua Mansur, Alessandra Roggerio, Júlio Yoshio Takada, Pérola Michelle Vasconcelos Caribé, Solange Desirée Avakian, Célia Maria Cassaro Strunz   +5 more
doaj   +2 more sources