Results 11 to 20 of about 12,125 (226)

Local tirofiban infusion for remnant stenosis in large vessel occlusion: tirofiban ASSIST study [PDF]

BMC Neurology, 2020
Background Compared with embolic occlusions, intracranial atherosclerotic stenosis (ICAS)-related large vessel occlusions (LVOs) often require rescue treatment following mechanical thrombectomy (MT).
Yong-Won Kim, Sung-Il Sohn, Joonsang Yoo, Jeong-Ho Hong, Chang-Hyun Kim, Dong-Hun Kang, Yong-Sun Kim, Seong-Joon Lee, Ji Man Hong, Jin Wook Choi, Yang-Ha Hwang, Jin Soo Lee   +11 more
doaj   +2 more sources

Radiolabeled tirofiban – a potential radiopharmaceutical for detection of deep venous thrombosis [PDF]

Drug Design, Development and Therapy, 2016
Marija Darkovska-Serafimovska,1,2 Emilija Janevik-Ivanovska,1 Icko Djorgoski,2 Zorica Arsova-Sarafinovska,1,3 Milka Zdravkovska,1 Trajan Balkanov,4 Nenad Ugresic5 1Department of Pharmacy, Faculty of Medical Sciences, Goce Delcev University, Stip ...
Darkovska-Serafimovska M, Janevik-Ivanovska E, Djorgoski I, Arsova-Sarafinovska Z, Zdravkovska M, Balkanov T, Ugresic N   +6 more
doaj   +2 more sources

Safety and Efficacy of Tirofiban in Severe Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

Journal of Cardiovascular Development and Disease, 2022
Tirofiban has recently shown encouraging efficacy and safety among acute ischemic stroke (AIS) patients with mechanical thrombectomy (MT). However, the benefits of tirofiban varied among studies depending on the patient’s condition, which was often not ...
Lingxin Cai, Tingting Wang, Aiqing Chen, Chenhan Ling, Jing Xu, Cong Qian, Gao Chen   +6 more
doaj   +2 more sources

Subtyping treatment response of tirofiban in acute ischemic stroke based on neuroimaging features

Clinical and Translational Science
In a previously published clinical trial, we demonstrated that tirofiban was effective and safe in acute ischemic stroke (AIS) patients who did not undergo early recanalization treatments.
Bin Han, Xu Man, Jian Ding, Yuzhu Li, Xintao Tian, Xuelian Zhu, Jiang Yu, Jinping Sun   +7 more
doaj   +2 more sources

Mechanical Solitaire Thrombectomy with Low-Dose Booster Tirofiban Injection [PDF]

Neurointervention, 2016
PurposeMechanical thrombectomy using a Solitaire stent has been associated with a high recanalization rate and favorable clinical outcome in intra-arterial thrombolysis.
Duck-Ho Goh, Sung-Chul Jin, Hae Woong Jeong, Sam Yeol Ha   +3 more
doaj   +3 more sources

Safety of tirofiban and dual antiplatelet therapy in treating intracranial aneurysms

Stroke and Vascular Neurology, 2019
Background Endovascular treatment of intracranial aneurysms usually involves stent-assisted coiling (SAC) and flow diverters. Glycoprotein IIb/IIIa inhibitors such as tirofiban and dual antiplatelet therapy (DAPT) are required to prevent thromboembolic ...
David M Hasan, Santiago Ortega-Gutierrez, Edgar A Samaniego, Pascal Jabbour, Jorge A Roa, Daichi Nakagawa, Mario Zanaty, Emilee Gibson   +7 more
doaj   +2 more sources

Impact of Preemptive vs. Conventional Tirofiban Administration on the Outcomes in Acute Branch Atheromatous Disease: A Propensity Score-Weighted Cohort Study. [PDF]

CNS Neurosci Ther
In acute branch atheromatous disease stroke, preemptive tirofiban within 72 h significantly raised the 90‐day excellent outcome rate (76.6% vs. 44.6%) and shortened hospitalization without increasing mortality or recurrence. Preemptive administration independently predicted favorable recovery, with enhanced neuroprotection in patients over 65 years ...
Li C, Jin Y, Liu X, Liu Y, Yang W, Wang Y, Ju D.   +6 more
europepmc   +2 more sources

Tirofiban-induced acute profound thrombocytopenia in endovascular therapy for acute ischemic stroke: a rare case report

BMC Neurology
Background Studies have shown that tirofiban (a glycoprotein IIb/IIIa receptor antagonist) is effective in the endovascular treatment of cerebrovascular diseases. However, it has also been reported that tirofiban can cause thrombocytopenia.
Jiuling Liu, Melysze Deanne Oorloff, Adithya Nadella, Yun Yan, Ning Zhou   +4 more
doaj   +2 more sources

Secondary risks of bleeding and associated outcome after tirofiban application during interventional treatment of intracranial aneurysms. [PDF]

Brain Spine
Introduction Device-assisted endovascular treatment of ruptured aneurysms may require antiplatelet therapy, but bleeding risk is a concern. This retrospective propensity score-matched cohort study investigated whether tirofiban, including prolonged ...
Griessmair M, Bodden J, Hedderich DM, Kirschke J, Maegerlein C, Renz M, Platzek P, Meyer B, Zimmer C, Wostrack M, Boeckh-Behrens T, Schwarting J.   +11 more
europepmc   +2 more sources

Pharmacosimulation of delays and interruptions during administration of tirofiban: a systematic comparison between EU and US dosage regimens. [PDF]

, 2022
Tirofiban is a glycoproteine (GP) IIb/IIIa receptor antagonist, which inhibits platelet-platelet aggregation and is a potential adjunctive antithrombotic treatment in patients with acute coronary syndromes (ACS) or high-risk percutaneous coronary ...
Karathanos, Athanasios, Gurbel, Paul A., Nia, Amir M., Masyuk, Maryna, Kelm, Malte, Muessig, Johanna M., Nia, Amir M, Tantry, Udaya S, Jung, Christian, Muessig, Johanna M, Polzin, Amin, Gurbel, Paul A, Tantry, Udaya S., Heramvand, Nadia, Valgimigli, Marco, Malte Kelm, Athanasios Karathanos, Marco Valgimigli, Johanna M. Muessig, Paul A. Gurbel, Maryna Masyuk, Amir M. Nia, Amin Polzin, Udaya S. Tantry, Christian Jung, Nadia Heramvand   +25 more
core   +2 more sources