Results 11 to 20 of about 6,226 (154)

Efficacy and Safety of Tirofiban for the Management of Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Randomized Controlled Trials (RCTs). [PDF]

Brain Behav
Graphical representation of the comparative efficacy and safety of intravenous tirofiban for acute ischemic stroke in randomized controlled trials. ABSTRACT Background: Tirofiban is a GP IIb/IIIa inhibitor, an anti‐platelet drug that is used in ischemic stroke or acute coronary syndromes.
Bullecer DL, Mohammed C, Loiola JAL, Chy MGT, Ramli SF, Hussein AS, Showkat WB, Taikadan T, Mutyala S, Ayyan M, Rehman MAU, Ahmad A, Alsubari AMA.   +12 more
europepmc   +2 more sources

Tirofiban-Associated Profound Thrombocytopenia in a Patient With Glucose-6-Phosphate Dehydrogenase Deficiency Undergoing Primary Percutaneous Coronary Intervention: A Case Report. [PDF]

Case Rep Cardiol
Background Profound thrombocytopenia after tirofiban exposure during primary percutaneous coronary intervention (PCI) is rare but clinically important. Causal attribution may be challenging when unfractionated heparin is coadministered, and the relevance of glucose‐6‐phosphate dehydrogenase (G6PD) deficiency remains uncertain.
Zhao C, Wang Y, Gao S, Meng W, Yang Y, Tan W.   +5 more
europepmc   +2 more sources

Platelet Function and Risk of Bleeding in Patients With Acute Coronary Syndrome Following Tirofiban Infusion

Frontiers in Pharmacology, 2019
Aim: To assess platelet (PLT) function and bleeding risks in patients with acute coronary syndrome after tirofiban infusion.Methods: Patients diagnosed with acute coronary syndrome from May 2016 to February 2018 in the Department of Cardiac Intensive ...
Xiaoye Li, Shuning Zhang, Zi Wang, Qiuyi Ji, Qibing Wang, Xiaoyu Li, Qianzhou Lv   +6 more
doaj   +1 more source

Influence of tirofiban on stroke outcome after mechanical thrombectomy in acute vertebrobasilar artery occlusion

BMC Neurology, 2022
Background Even undergoing mechanical thrombectomy (MT), patients with acute vertebrobasilar artery occlusion (AVBAO) still have a high rate of mortality.
Xiding Pan, Mengyi Xu, Yuxiang Fei, Shiteng Lin, Yapeng Lin, Jianjun Zou, Jie Yang   +6 more
doaj   +1 more source

Safety and efficacy of low-dose and long-course tirofiban in large hemispheric infarction

Frontiers in Neurology, 2022
BackgroundThe clinical efficacy and safety of tirofiban in the treatment of large hemispheric infarction (LHI) remain controversial.MethodsThis study prospectively enrolled patients with acute LHI who were admitted to Putuo Hospital affiliated with ...
Yinqin Hu, Qian Xiao, Zhizhen Shi, Yangbo Hou, Zhen Chen, Jiwei Cheng, Guoyi Li   +6 more
doaj   +1 more source

Tirofiban for Preventing Early Neurological Deterioration in Acute Ischemic Stroke Within 48 Hours of Onset: Evidence From a Dual-Method Analysis Using Propensity Score Matching and Multivariable Regression. [PDF]

CNS Neurosci Ther
Previous studies have shown that tirofiban may reduce the risk of early neurological deterioration within 24 h after symptom onset in patients with acute ischemic stroke (AIS). However, evidence on its efficacy beyond this time window is limited. This study suggests that tirofiban may still confer potential therapeutic benefits in AIS patients without ...
Wen Q, Zhao Y, Deng Y, Guan S, Zhang S, Zhou J, Zhu P, Fan X, Li J, Chen Y, Cai G, Huang Y, Zheng S, Meng H.   +13 more
europepmc   +2 more sources

Influence of Tirofiban maintenance duration on patients with acute myocardial infarction treated by percutaneous coronary intervention

Chronic Diseases and Translational Medicine, 2015
Objective: To evaluate the efficacy and short term prognosis of Tirofiban in different treatment duration in patients with acute ST segment elevation myocardial infarction (STEMI) and percutaneous coronary intervention (PCI) combined with intracoronary ...
Zhen-Guo Ji, Hong-Bin Liu, Zhi-Hong Liu, Guo-Ping Ma, Li-Qiang Qin, Wei Dong, Li-Ya Wang   +6 more
doaj   +1 more source

The Safety and Efficiency of Tirofiban in Acute Ischemic Stroke Patients Treated with Mechanical Thrombectomy: A Multicenter Retrospective Cohort Study

Biochemistry Research International, 2020
Introduction. Limited comparative studies have reported the safety and efficacy of tirofiban in acute ischemic stroke (AIS) patients after mechanical thrombectomy (MT).
Lili Zhao, Yating Jian, Tao Li, Heying Wang, Zhang Lei, Man Sun, Ye Li, Yiheng Zhang, Meijuan Dang, Wang Huqing, Sun Hong, Zhang Ru, Hongxing Zhang, Yi Jia, Luo Guogang, Zhang Guilian   +15 more
doaj   +1 more source

Safety and Efficacy of Tirofiban in Severe Ischemic Stroke Patients Undergoing Mechanical Thrombectomy

Journal of Cardiovascular Development and Disease, 2022
Tirofiban has recently shown encouraging efficacy and safety among acute ischemic stroke (AIS) patients with mechanical thrombectomy (MT). However, the benefits of tirofiban varied among studies depending on the patient’s condition, which was often not ...
Lingxin Cai, Tingting Wang, Aiqing Chen, Chenhan Ling, Jing Xu, Cong Qian, Gao Chen   +6 more
doaj   +1 more source

Long-Term Outcomes of Local Tirofiban Infusion for Intracranial Atherosclerosis-Related Occlusion

Brain Sciences, 2022
Local tirofiban infusion has been reported as a rescue strategy for intracranial atherosclerotic stenosis (ICAS)-related stroke. However, the long-term outcomes of local tirofiban infusion during endovascular reperfusion therapy (ERT) for ICAS-related ...
Woochan Choi, Yang-Ha Hwang, Yong-Won Kim   +2 more
doaj   +1 more source