Results 111 to 120 of about 12,434,864 (335)

Analysis of rabbit cell surface (CD) antigens by means of cross-reactive monoclonal antibodies with specificity for cattle CD antigens

Czech Journal of Animal Science, 2009
Studies that involved testing monoclonal antibodies (mAbs) for cross-species reactivity proved to be efficient for the identification of previously unrecognized antigens in a number of different species.
M. Simon, J. Antalíková, Ľ. Horovská, J. Jankovičová, K. Fábryová, S. Hluchý, P. Chrenek, V. Tančin   +7 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Tissue culture isolation, electron microscopic characterization and PCR-detection of a betanodavirus isolated from diseased Asian sea bass. [PDF]

, 2010
A viral agent was successfully isolated from Asian sea bass juveniles (Letes calcarifer) exhibiting clinical signs of viral nervous necrosis (VNN) in southern Malaysia on February 2008. Eyes and brains of diseased fish were pooled, extracted and filtered.
Arshad, Siti Suri, Bejo, Mohd Hair, F. Hasoon, Mauida, Mohd. Daud, Hassan   +3 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Subprodutos do maracujá em dietas para frangos de corte = Passion fruit by-products in broiler diets

Acta Scientiarum: Animal Sciences, 2008
Um experimento foi realizado com 200 frangos de corte machos da linhagem Cobb, a fim de avaliar desempenho, características de carcaça e teores de colesterol em tecidos e soro quando alimentados com rações compostas por milho e farelo de soja ...
Cristina Kimie Togashi, José Brandão Fonseca, Rita da Trindade Ribeiro Nobre Soares, Ana Paula Delgado da Costa, Karla Ferreira da Silveira, Edenio Detmann   +5 more
doaj  

Targeting Strategies for the Combination Treatment of Cancer Using Drug Delivery Systems

Pharmaceutics, 2017
Cancer cells have characteristics of acquired and intrinsic resistances to chemotherapy treatment—due to the hostile tumor microenvironment—that create a significant challenge for effective therapeutic regimens.
Janel Kydd, Rahul Jadia, Praveena Velpurisiva, Aniket Gad, Shailee Paliwal, Prakash Rai   +5 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Panfacial trauma: management of a traumatic hemifacial avulsion and degloving injury with multiple maxillofacial fractures [PDF]

Archives of Trauma Research
Background: Cases of avulsion and degloving injuries of solitary areas of the face have been reported in the literature. However, complex traumatic degloving hemifacial injury with compound panfacial fractures is very rare.
Pulkit Khandelwal, Harish Saluja, Seemit Shah, Anuj Dadhich, Niharika Dubey   +4 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source