Mediators of Inflammation, 2011 We have investigated whether an oxygen/ozone (95%O2/5%O3) mixture would have potential against the formation of experimental postsurgical peritoneal adhesions.
Clara Di Filippo +6 more
doaj +1 more source
Battling adhesions: from understanding to prevention
BMC Biomedical Engineering, 2019 Adhesions represent a major burden in clinical practice, particularly following abdominal, intrauterine, pericardial and tendon surgical procedures. Adhesions are initiated by a disruption in the epithelial or mesothelial layer of tissue, which leads to ...
Héctor Capella-Monsonís +3 more
doaj +1 more source
Collective cell durotaxis emerges from long-range intercellular force transmission [PDF]
, 2016 The ability of cells to follow gradients of extracellular matrix stiffness—durotaxis—has been implicated in development, fibrosis, and cancer. Here, we found multicellular clusters that exhibited durotaxis even if isolated constituent cells did not. This
Conte, V +10 more
core +2 more sources
CaproGlu: Multifunctional tissue adhesive platform
Biomaterials, 2020 Driven by the clinical need for a strong tissue adhesive with elastomeric material properties, a departure from legacy crosslinking chemistries was sought as a multipurpose platform for tissue mending. A fresh approach to bonding wet substrates has yielded a synthetic biomaterial that overcomes the drawbacks of free-radical and nature-inspired ...
Djordjevic, Ivan +16 more
openaire +4 more sources
Pharmacological HIF-inhibition attenuates postoperative adhesion formation
Scientific Reports, 2017 Peritoneal adhesions represent a common complication of abdominal surgery, and tissue hypoxia is a main determinant in adhesion formation. Reliable therapeutic options to reduce peritoneal adhesions are scarce.
Moritz J. Strowitzki +12 more
doaj +1 more source
Adhesions in the epidural space caused by frequent epidural blocks
JA Clinical Reports, 2017 We report a case of adhesions in the epidural space caused by more than 200 times epidural blocks that were observed with epiduroscopy. A 41-year-old man had repeatedly undergone lumbar epidural blocks to treat pain in his leg, resulting in decreased ...
Nobuhiro Shimada +5 more
doaj +1 more source
A first-in-human, randomized, controlled, subject- and reviewer-blinded multicenter study of Actamax™ Adhesion Barrier [PDF]
, 2016 Purpose: Post-surgical adhesions remain a significant concern following abdominopelvic surgery. This study was to assess safety, manageability and explore preliminary efficacy of applying a degradable hydrogel adhesion barrier to areas of surgical ...
Brucker, Sara Y. +12 more
core +2 more sources
Meloxicam Decreases the Formation of Peritoneal Adhesions in an Experimental Surgical Model in Rats
International Journal of Medical Students, 2017 Background: Inflammatory adhesions result from an inflammatory response of the peritoneum during an intra-abdominal inflammatory process secondary to thermal or mechanical injury, infection, radiation, ischemia, dissection, abrasion or foreign body ...
Luis Alfredo Hernandez Villarroel +2 more
doaj +1 more source
α5β1-Integrin promotes tension-dependent mammary epithelial cell invasion by engaging the fibronectin synergy site. [PDF]
, 2017 Tumors are fibrotic and characterized by abundant, remodeled, and cross-linked collagen that stiffens the extracellular matrix stroma. The stiffened collagenous stroma fosters malignant transformation of the tissue by increasing tumor cell tension to ...
Cassereau, L +11 more
core +2 more sources
Technical Development of a New Semispherical Radiofrequency Bipolar Device (RONJA): Ex Vivo and In Vivo Studies [PDF]
, 2014 The aim of this study is to inform about the development of a new semispherical surgical instrument for the bipolar multielectrode radiofrequency liver ablation.
Crha, M +14 more
core +5 more sources