Results 61 to 70 of about 94,902 (266)

Antiadhesive Nanofibrous Materials for Medicine: Preventing Undesirable Tissue Adhesions. [PDF]

ACS Omega, 2023
Klicova M, Rosendorf J, Erben J, Horakova J.   +3 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Predicting Intra-Abdominal Adhesions in Repeat Cesarean Sections: Scar Tissue Characteristics, Striae Gravidarum, and Corset Use

Clinical and Experimental Obstetrics & Gynecology
Background: This study evaluated whether abdominal scar tissue characteristics, duration of corset use, and striae gravidarum (SG) density are associated with the severity of intra-abdominal adhesions (IAA) in repeat cesarean sections (
Yusuf Ziya Kizildemir, Hacer Uyanikoglu, Ömer Tammo, Mehmet İncebiyik, Bekir Kahveci   +4 more
doaj   +1 more source

Informativeness of phenotypic features of connective tissue dysplasia in children with peritoneal adhesions

Galician Medical Journal, 2016
Connective tissue dysplasia can be realized with a large number of clinical variants, and accordingly, excessive postoperative adhesion formation can be considered as a manifestation of dysplastic-dependent processes.
M. G. Melnichenko, A. A. Kvashnina
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Bronchial anastomosis with a tissue adhesive

The Journal of Thoracic and Cardiovascular Surgery, 1987
Air leakage and necrotic degeneration may occur after bronchial anastomosis and can lead to death from secondary pneumothorax and pneumonia. We studied the ability of a new tissue adhesive (N-butyl-cyanoacrylate monomer) to enforce the bronchial suture line.
M, Hachida, P, Naruns, S, Morris, I, Irie, A J, Cochran, D L, Morton   +5 more
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

NETworking for Health and in Disease: Neutrophil Extracellular Traps in Pediatric Surgical Care

Children
This comprehensive review examines the role of Neutrophil Extracellular Traps (NETs) in pediatric surgery. Focusing on NET formation, functions, and implications, this study highlights their dual impact in infection control and contribution to tissue ...
Maximilian Dölling, Martin Herrmann, Michael Boettcher   +2 more
doaj   +1 more source

Effectiveness of Seprafilm in Reducing Postoperative Adhesions after Abdominopelvic Surgery: A Prospective Interventional Study [PDF]

Journal of Clinical and Diagnostic Research
Introduction: Postoperative adhesions are indeed a significant concern following abdominopelvic surgeries. These fibrous bands of tissue can form between abdominal or pelvic organs and tissues, leading to various complications.
M Malarmannan, A Pravindhas, Debarath Das, R Lakshmana, N Soorya, N Snigdha   +5 more
doaj   +1 more source