Results 61 to 70 of about 36,410 (330)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Challenges of Organ Shortage for Transplantation: Solutions and Opportunities

International Journal of Organ Transplantation Medicine, 2014
Organ shortage is the greatest challenge facing the field of organ transplantation today. A variety of approaches have been implemented to expand the organ donor pool including live donation, a national effort to expand deceased donor donation, split ...
RF Saidi, SK Hejazii Kenari
doaj  

Nurse’s life world in organ donation and tissue [PDF]

Revista Brasileira de Enfermagem
Objectives: to understand the experience of nurses immersed in the everyday world of organ and tissue donation. Methods: study on the social phenomenology of Alfred Schütz, carried out with 27 nurses who work on Intra-Hospital Committees for Donation of
Karine de Melo Cezar Alves, Isabel Comassetto, Guilherme Oliveira de Albuquerque Malta, Regina Maria dos Santos, Gian Carlos Rodrigues do Nascimento, Igor Michel Ramos dos Santos   +5 more
doaj   +1 more source

Improvement of lung preservation - From experiment to clinical practice [PDF]

, 2002
Background. Reperfusion injury represents a severe early complication following lung transplantation. Among the pathogenetic factors, the high potassium content of Euro-Collins(R) solution is discussed.
Bittmann, I., Fürst, H., Hatz, Rudolf A., Kellner, B., Müller, Ch., Reichart, B., Schelling, G., Schildberg, Friedrich Wilhelm   +7 more
core   +1 more source

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Attitude and Performance of Staff Working in Educational Hospitals Regarding Organ Donation

Journal of Holistic Nursing and Midwifery, 2017
Introduction: The demand for organ donation has increased in most countries of the world, while the number of donors remains relatively stable. Objective: The aim of this study was to determine the attitude and performance of physicians and nurses in ...
Mahasti Emami, Kobra Salami Kohan, Asieh Sedighi Chafjiri, Ehsan Kazem Nezhad Leyli, Pardis Rahmat Poor   +4 more
doaj  

Establishing a deceased donor transplantation program and its impact in a public sector hospital in India – A single centre experience from India

Indian Journal of Transplantation, 2020
Introduction: Organ transplantation is growing in India but is mostly dependent on living donors. Deceased donor organ procurement has grown in certain parts of the country in the past decade.
JIPMER Deceased Donor Transplantation Committee (JDDTC)
doaj   +1 more source

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

Ovarian Tissue Procurement from Organ Donor v1 [PDF]

, 2023
pooja.devrukhkar not provided, hannah.anvari not provided, asma.giornazi Asma Giornazi, shriya.shah not provided, maryellen.pavone not provided, Francesca E. Duncan   +5 more
openalex   +1 more source

Governing the post mortem procurement of human body material for research [PDF]

, 2015
Human body material removed post mortem is a particularly valuable resource for research. Considering the efforts that are currently being made to study the biochemical processes and possible genetic causes that underlie cancer and cardiovascular and ...
Capitaine, Laura, Pennings, Guido, Sterckx, Sigrid, Van Assche, Kristof   +3 more
core   +1 more source