Results 211 to 220 of about 61,211 (254)

A Dynamic 3D Human Liver Sinusoid Model for Mechanistic Interrogation of Fontan‐Associated Liver Disease

Advanced Science, EarlyView.
This study presents a perfusable 3D bioengineered liver sinusoid platform that integrates biofabrication, 3D cell culture, controlled hemodynamics, and multiparametric characterization to model Fontan‐associated liver disease. By decoupling pressure and hypoxia effects, the system reveals early mechanobiological and profibrotic responses under ...
Sarah Rezapourdamanab, Mehdi Salar Amoli, Tanmay Mukherjee, Maryam Bagheri, Boeun Hwang, Linqi Jin, Yamini Singh, Sophia Norton, Ashay Vishwas Bongirwar, Shweta Karnik, Lakshmi Prasad Dasi, Reza Avazmohammadi, Rene Romero, Holly D. Bauser‐Heaton, Vahid Serpooshan   +14 more
wiley   +1 more source

Expansion Microscopy of the Enteric Nervous System: A Feasibility Study. [PDF]

Cells
Xu X, Zhang W, Hanani M.
europepmc   +1 more source

Functional Disorder at the Neural Interface: How Disordered Nanostructures Promote Proper Growth and Differentiation in In Vitro Neural Cultures

Advanced Science, EarlyView.
This work provides a practical guide for neuroengineers to design advanced neural interfaces, embracing and tailoring the concept of functional disorder. By bridging 2D and 3D in vitro models, this work highlights how non‐periodic, spatially heterogeneous, multiscale nanotopography can enable more physiologically relevant platforms for studying neural ...
F. Maita, E. Palmieri, I. Lucarini, L. Montaina, L. Maiolo   +4 more
wiley   +1 more source

White matter microstructure differences between 15q11.2 copy number variation carriers and non-carriers in mid-to-late life. [PDF]

Transl Psychiatry
Korbmacher M, Boen R, Andreassen OA, Westlye LT, Sønderby IE, Maximov II.   +5 more
europepmc   +1 more source

Harnessing Phase Separation for the Development of High‐Performance Hydrogels

Advanced Science, EarlyView.
ABSTRACT Hydrogels are indispensable for the development of next‐generation bioelectronics, soft robotics, and biomedical devices, where their mechanical properties determine performance and reliability. Among strategies to enhance hydrogel mechanics, phase separation enables controlled heterogeneity resulting in gel networks that are reinforced by ...
Yue Shao, Yiming Ma, Baihao Shao, Molly M. Stevens   +3 more
wiley   +1 more source

Innovations in collagen-network remodeling and extracellular matrix mechanics: toward a new era in articular cartilage repair. [PDF]

Front Bioeng Biotechnol
Huang K, Hong Y, Cai H.
europepmc   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Myelin water and tensor-valued diffusion imaging: (How) are they related? [PDF]

Magn Reson Med
Balaji S, Dvorak AV, Wiley N, MacMillan EL, Traboulsee A, Vavasour IM, Gilbert G, Moore GRW, Li DKB, Laule C, MacKay AL, Kolind S.   +11 more
europepmc   +1 more source

Ultrasound-responsive Janus patch with mechanical anisotropy, pro-healing, and anti-adhesion properties for abdominal wall defect repair. [PDF]

J Nanobiotechnology
Peng B, Ma B, Lu H, Chen Z, Xiong W, Wang H, Cai Z, Shi X, Huang R.   +8 more
europepmc   +1 more source

Learning to simulate realistic human diffuse reflectance spectra. [PDF]

J Biomed Opt
Hübner M, Bin Qasim A, Studier-Fischer A, Rees M, Tran Ba V, Nölke JH, Seidlitz S, Sellner J, Heinecke J, Brandt J, Özdemir B, Dreher K, Seitel A, Nickel F, Max Haney C, Kowalewski KF, Ayala L, Maier-Hein L.   +17 more
europepmc   +1 more source