Results 231 to 240 of about 1,922,235 (275)

Osteoclast visualization: Tartrate-resistant acid phosphatase activity staining using NewFuchsin compatible with non-aqueous mounting and tissue clearing. [PDF]

MethodsX
Nakamura T, Kawaai K, Kuroda Y, Matsuo K.   +3 more
europepmc   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

Immunolabeling-compatible PEGASOS tissue clearing for high-resolution whole mouse brain imaging. [PDF]

Front Neural Circuits
Gao P, Rivera M, Lin X, Holmes TC, Zhao H, Xu X.   +5 more
europepmc   +1 more source

A robust vessel-labeling pipeline with high tissue clearing compatibility for 3D mapping of vascular networks. [PDF]

iScience
Deng Y, Zhu J, Liu X, Dai J, Yu T, Zhu D.   +5 more
europepmc   +1 more source

Increased Multiplexity in Optical Tissue Clearing-Based Three-Dimensional Immunofluorescence Microscopy of the Tumor Microenvironment by Light-Emitting Diode Photobleaching. [PDF]

Lab Invest
Zheng J, Wu YC, Phillips EH, Cai X, Wang X, Seung-Young Lee S.   +5 more
europepmc   +1 more source

Preparation and Characterization of Acrylic and Methacrylic Phospholipid-Mimetic Polymer Hydrogels and Their Applications in Optical Tissue Clearing. [PDF]

Polymers (Basel)
Dei N, Ishihara K, Matsumoto A, Kojima C.   +3 more
europepmc   +1 more source

Efficacy and Feasibility of Tissue-Clearing Technique and Three-Dimensional Imaging in the Human Gastrointestinal Tissues Using Illuminate Cleared Organs to Identify Target Molecules.

Dig Dis
Mizutani H, Ono S, Miura Y, Ohki D, Takeuchi C, Tsuji Y, Yamamichi N, Onodera H, Fujishiro M.   +8 more
europepmc   +1 more source

Tissue clearing [PDF]

Nature Reviews Methods Primers, 2021
Tissue clearing of gross anatomical samples was first described more than a century ago and has only recently found widespread use in the field of microscopy.
Ali Ertürk, Hiroki R Ueda, Jeff W. Lichtman   +2 more
exaly   +7 more sources

Clarifying Tissue Clearing [PDF]

Cell, 2015
Biological specimens are intrinsically three dimensional; however, because of the obscuring effects of light scatter, imaging deep into a tissue volume is problematic.
Jeff W. Lichtman, Douglas Richardson
exaly   +5 more sources

A beginner’s guide to tissue clearing [PDF]

International Journal of Biochemistry and Cell Biology, 2017
The last decade has seen a proliferation of tissue clearing methods that render large biological samples transparent and allow unprecedented three-dimensional views of enormous volumes of tissue.
Pablo Ariel
exaly   +5 more sources