Results 251 to 260 of about 177,664 (273)

Tissue Clearing Approaches in Atherosclerosis

2022
Recent advances in cardiovascular research have led to a more comprehensive understanding of molecular mechanisms of atherosclerosis. It has become apparent that the disease involves three layers of the arterial wall: the intima, the media, and a connective tissue coat termed the adventitia.
Sun, T., Li, Y., Förstera, B., Stanic Aguilera, K.N., Lu, S., Steffens, S., Yin, C., Ertürk, A., Megens, R.T.A., Weber, C., Habenicht, A.J., Mohanta, S.K.   +11 more
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Clearing Tissue Homogenates

Nature, 1962
THE separation, isolation and identification of the protein fractions in different tissues have recently been of ever-increasing interest, because of the possibility of isolating biologically very active fractions, for example, serum protein fractions from placental tissue1 or fractions which influence the coagulation system2.
A, HANSEN, J, CLAUSEN, R, JENSEN
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Tissue optical immersion clearing

Expert Review of Medical Devices, 2010
In this article, we discuss the optical immersion method based on refractive index matching of scatterers (e.g., collagen, elastin fibers, cells and cell compartments) and the ground material (interstitial fluid and/or cytoplasm) of tissue and blood under the action of exogenous optical clearing agents.
Elina A, Genina, Alexey N, Bashkatov, Valery V, Tuchin   +2 more
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Ethyl Cinnamate-Based Tissue Clearing Strategies

2022
Tissue clearing turns otherwise turbid and opaque tissue transparent, enabling imaging deep within tissues. The nontransparent nature of most tissues is due to the refractive index mismatch between its three major constituent components (lipids, proteins, and water). All tissue clearing methods rectify this mismatch by homogenizing the refractive index
Wouter, Masselink, Elly M, Tanaka
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Tissue Clearing for Optical Anatomy

Angewandte Chemie International Edition, 2013
Quest for transparency: Detailed optical imaging of complex biological entities remains an unmet goal mainly because of the light scattering of biological tissue. A new approach to tissue clearing termed CLARITY is getting us closer to an anatomical view of thick tissues and entire organs with cellular resolution.
Dmytro A, Yushchenko, Carsten, Schultz
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Liposome Imaging in Optically Cleared Tissues

Nano Letters, 2020
Three-dimensional (3D) optical microscopy can be used to understand and improve the delivery of nanomedicine. However, this approach cannot be performed for analyzing liposomes in tissues because the processing step to make tissues transparent for imaging typically removes the lipids. Here, we developed a tag, termed REMNANT, that enables 3D imaging of
Abdullah Muhammad Syed, Presley MacMillan, Jessica Ngai, Stefan Wilhelm, Shrey Sindhwani, Benjamin R. Kingston, Jamie L. Y. Wu, Pablo Llano-Suárez, Zachary Pengju Lin, Ben Ouyang, Zaina Kahiel, Suresh Gadde, Warren C. W. Chan   +12 more
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Optical clearing for multiscale biological tissues

Journal of Biophotonics, 2017
Three‐dimensional reconstruction of tissue structures is essential for biomedical research. The development of light microscopes and various fluorescent labeling techniques provides powerful tools for this motivation. However, optical imaging depth suffers from strong light scattering due to inherent heterogeneity of biological tissues.
Tingting Yu, Yisong Qi, Hui Gong, Qingming Luo, Dan Zhu   +4 more
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Clear Cell Tumors of Soft Tissue

Surgical Pathology Clinics, 2011
Clear cell lesions of soft tissue include varying morphologic patterns and a range of clinical behaviors and prognoses. Benign lesions include perivascular epithelioid cell tumors, clear cell fibrous papule, and distinctive dermal clear cell mesenchymal tumor; malignant tumors include clear cell sarcoma, liposarcoma, and rare malignant perivascular ...
Aaron, Auerbach, David S, Cassarino
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Clear cell sarcoma of soft tissues

Journal of Surgical Oncology, 2006
AbstractClear cell sarcoma (CCS) is a rare but highly malignant tumor of soft tissues often appearing as a small tender mass in the deep tissues of the distal extremities. We have studied 17 patients with such lesions treated since 1986 and have a high incidence of local recurrence and metastasis with a survival rate of only 47% despite surgery and for
Sara Sofia, Malchau, James, Hayden, Francis, Hornicek, Henry J, Mankin   +3 more
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