Results 121 to 130 of about 2,255,345 (306)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Mass propagation and ex vitro survival of banana cv. 'Basrai' through tissue culture
European Journal of Horticultural Science, 2000 Dilip Nandwani +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Risk assessment of spreading Banana streak viruses in the Dominican Republic through large scale cultivation of plantain cultivars and hybrids harbouring infectious eBSVs. [O.33] [PDF]
, 2015 Most cultivated plantains are interspecific cultivars or hybrids: they harbour Musa acuminata (A) genomes and Musa balbisiana (B) genomes which hosts infectious endogenous Banana streak virus sequences (eBSVs).
Acina Manbole, Isabelle Nina +5 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Lattice and Continuum Modelling of a Bioactive Porous Tissue Scaffold
, 2018 A contemporary procedure to grow artificial tissue is to seed cells onto a porous biomaterial scaffold and culture it within a perfusion bioreactor to facilitate the transport of nutrients to growing cells.
Beliaev, Dmitry +3 more
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新規蛍光プローブ探索のための C2C12 細胞を用いた機能性組織の再構築 [PDF]
, 2018 The second near-infrared window ranged between 900 and 1400 nm, namely NIR-II, has advantages for deep tissue imaging with extrinsic fluorophores due to lacking autofluorescence, low light absorption, and reduced scattering.
Jin, Takashi +8 more
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