Results 121 to 130 of about 6,903,081 (310)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Breast Cancer Tissue Bank Sample and Image Collection

This is a collection of samples of breast cancer and normal breast, also including images of tissue samples, and blood samples. Samples and images are made available from the Breast Cancer Tissue Bank for research into breast cancer including its causes,

core  

Potential of tissue cultured medicinal plants in Malaysia [PDF]

, 2013
Medicinal plants possess many secondary products that exhibit biological activities such as antioxidant, anticancer, anti-inflammatory, antibacterial and anti microbial.
Abd Samad, Azman, Ayob, Zahidah, Wagiran, Alina   +2 more
core  

Primary tissue culture of normal adult rabbit adrenocortical cells from zonae fasciculata and reticularis.

, 1988
A novel method is reported for the primary tissue culture of normal adult rabbit adrenocortical cells from zonae fasciculata and ...
MENAPACE, Lia, ARMATO, Ubaldo
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Gibberellic acid-induced changes in glutathione metabolism and anthocyanin content in plant tissue

, 2001
Literature data point to a possible link between gibberellic acid (GA(3)) and glutathione metabolism in plant tissue, as both are connected to dormancy breakage.
Berglund, Torkel,, Ohlsson, Anna B.,
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Maintenance and characterization of human myometrial smooth muscle cells in monolayer culture

, 1984
Human myometrial cells were dispersed from uterine tissue by limited enzymatic digestion of myometrium that was obtained at the time of hysterectomy. The dispersed myometrial cells that are obtained in this manner can be maintained in monolayer culture ...
Snyder, Jeanne M., Mitchell, Murray D., Casey, M. Linette, MacDonald, Paul C.   +3 more
core   +1 more source

Impact of Exogenous Cytokinin and Auxin on In Vitro Culture of Pineapple (Ananas comosus) (L) var Sweet Cayenne Under Aseptic Conditions

Advances in Agriculture
An efficient micropropagation technique for pineapple utilizes shoot crowns as an explant. Traditional propagation methods are slow and insufficient for large-scale production due to the small number of suckers naturally produced by the plant. This study
Samuel C. Chukwu, Eufenia Arexandra, Fortonato P. Ngonga, Gervasius Hatutale   +3 more
doaj   +1 more source