Results 101 to 110 of about 6,903,081 (310)

The influence of serum-free culture conditions on skeletal muscle differentiation in a tissue-engineered model

, 2008
The influence of differentiation medium (DM) components on C2C12 murine myoblast differentiation has only been studied in monolayer cultures. Serum-free formulations have been applied that omit the use of sera with unknown composition.
Baaijens, FPT Frank, Boonen, KJM Kristel, Oomens, CWJ Cees, Bouten, C.V.C., Bouten, C.V.C.; id_orcid, Gawlitta, D Debby, Bouten, CVC Carlijn, Boonen, K.J.M., Oomens, C.W.J., Baaijens, F.P.T., Gawlitta, D.   +10 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Hormone-responsive 3D multicellular culture model of human breast tissue

, 2012
A hormone-responsive 3D human tissue-like culture system was developed in which human primary mammary epithelial cells (MECs) were co-cultured with two types of predominant mammary stromal cells on silk protein scaffolds.
Kaplan, David L., Wang, Xiuli, DavidLKaplan   +2 more
core   +1 more source

GC–MS analysis underpins ethnomedicinal properties of Rhododendron flower brews from Singalila Himalaya highlighting the anticipated biosynthesis pathways of the bioactives

Discover Food
Guras or Rhododendron wine and its Raksi are popular and therapeutic traditional drinks served in the rhododendron growing regions of the Himalayas; mainly in northern and north eastern part of India, Nepal and Indo-Nepal Singalila ridge.
Soumya Majumder, Arindam Ghosh, Malay Bhattacharya   +2 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

BCTB Fresh Tissue Samples

This BCTB tissue subcollection consists of fresh tissue samples, that is, pieces of tissue placed in liquid nitrogen for freezing.

core  

Low oxygen concentrations impair tissue development in tissue-engineered cardiovascular constructs

, 2012
Cardiovascular tissue engineering has shown considerable progress, but in vitro tissue conditioning to stimulate the development of a functional extracellular matrix still needs improvement.
Baaijens, FPT Frank, Vlimmeren, M.A.A. van, Stoop, R, Broek, van den, W.J.T., Driessen - Mol, A., Bouten, C.V.C., Bouten, CVC Carlijn, Stoop, R., Baaijens, F.P.T., Vlimmeren, van, M.A.A., Driessen-Mol, A Anita, Oomens, CWJ Cees, Bouten, C.V.C.; id_orcid, Broek, M. van den, Driessen-Mol, A., Oomens, C.W.J., Vlimmeren, MAA Marijke van, Broek, WJT van den   +17 more
core   +1 more source

Asymbiotic Seed Germination and In Vitro Propagation of the Thai Rare Orchid Species; Eulophia bicallosa (D.Don) P.F.Hunt & Summerh.

Plants
An efficient in vitro propagation protocol for Eulophia bicallosa was developed using asymbiotic seed germination and protocorm proliferation. The effect of light on seed germination and development was evaluated on Vacin and Went (VW) medium under five ...
Thanakorn Wongsa, Jittra Piapukiew, Kanlaya Kuenkaew, Chatchaya Somsanook, Onrut Sapatee, Julaluk Linjikao, Boworn Kunakhonnuruk, Anupan Kongbangkerd   +7 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source