Results 131 to 140 of about 9,392,969 (335)

Asymbiotic Seed Germination and In Vitro Propagation of the Thai Rare Orchid Species; Eulophia bicallosa (D.Don) P.F.Hunt & Summerh.

open access: yesPlants
An efficient in vitro propagation protocol for Eulophia bicallosa was developed using asymbiotic seed germination and protocorm proliferation. The effect of light on seed germination and development was evaluated on Vacin and Went (VW) medium under five ...
Thanakorn Wongsa   +7 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

GC–MS analysis underpins ethnomedicinal properties of Rhododendron flower brews from Singalila Himalaya highlighting the anticipated biosynthesis pathways of the bioactives

open access: yesDiscover Food
Guras or Rhododendron wine and its Raksi are popular and therapeutic traditional drinks served in the rhododendron growing regions of the Himalayas; mainly in northern and north eastern part of India, Nepal and Indo-Nepal Singalila ridge.
Soumya Majumder   +2 more
doaj   +1 more source

Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures [PDF]

open access: bronze, 2015
Franziska E. Uhl   +9 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Medicinal orchids and their uses: Tissue culture a potential alternative for conservation

open access: yes, 2013
Orchids are nature's most extravagant group of flowering plants distributed throughout the world from tropics to high alpine. They exhibit incredible range of diversity in size, shape and color of their flowers.
B. Pant
semanticscholar   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Toxicity Effect of Silver Nanoparticles in Brine Shrimp Artemia

open access: yesThe Scientific World Journal, 2014
The present study revealed the toxic effect of silver nanoparticles (AgNPs) in Artemia nauplii and evaluated the mortality rate, hatching percentage, and genotoxic effect in Artemia nauplii/cysts.
Chinnasamy Arulvasu   +3 more
doaj   +1 more source

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