Advanced Biology, EarlyView.The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna +6 more
wiley +1 more source
Field evaluation of tissue culture-derived and offshoot-grown date palm cultivars: a comparative analysis of vegetative and fruit attributes. [PDF]
Front Plant SciSolangi N +7 more
europepmc +1 more source
A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study
Advanced Biology, EarlyView.Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers +10 more
wiley +1 more source
Tissue Culture Innovations for Propagation and Conservation of Myrteae-A Globally Important Myrtaceae Tribe. [PDF]
Plants (Basel)Bao J +5 more
europepmc +1 more source
Differentiation Treatment Applied to Lung Cancer Model Reduces Pathogenic Traits in Vitro
Advanced Biology, EarlyView.Non‐small cell lung cancer cells (A549) treated with a differentiation medium showed strong reduction in proliferation, migration, clonogenicity, spheroid formation and stemness markers, with enhanced adhesion properties and alveolar features, all pointing to a notably less aggressive phenotype in support of differentiation therapy as a promising ...
Alice Grossi +10 more
wiley +1 more source
Advanced Biology, EarlyView.In this study, Seaman et al. develop a co‐culture assay to examine interactions between prostate cancer cells and mineralized osteoblasts in a microfluidic platform. The authors collect conditioned media from static or flow‐stimulated osteocytes and demonstrate that mechanical loading of osteocytes regulates the growth of prostate cancer cells and ...
Kimberly Seaman +5 more
wiley +1 more source
Exploration of Suitable Conditions for Shoot Proliferation and Rooting of <i>Quercus robur</i> L. in Plant Tissue Culture Technology. [PDF]
Life (Basel)Wang T +6 more
europepmc +1 more source
Osteogenic Effects of Ion Released from Biodegradable Metallic Magnesium and Calcium Coating
Advanced Biology, EarlyView.This study explores how magnesium–calcium coatings on titanium promote osteogenesis by releasing ions and elevating pH during degradation. Using osteoblast‐like cells, the research demonstrates that both ion release and pH changes contribute to cell proliferation, differentiation, and mineralization, offering new insights into the design of bioactive ...
Risa Miyake +4 more
wiley +1 more source
Advancements in delivery strategies and non-tissue culture regeneration systems for plant genetic transformation. [PDF]
Adv Biotechnol (Singap)Wu M, Chen A, Li X, Li X, Hou X, Liu X.
europepmc +1 more source