Results 111 to 120 of about 1,427,308 (312)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Cancerous Tissue Diagnosis by LIF Spectroscopy Derived From Body-Compatible Fluorophores. [PDF]

J Lasers Med Sci, 2021
Asghari Moghaddam A, Sajad B, Mehrad Nia F, Madani SH.   +3 more
europepmc   +1 more source

Molecular pathology assists the diagnosis of lymphoepithelial sialadenitis, Sjögren's syndrome and extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue

, 2023
Yanting Chi, Q M Zhang, Zhiming Qin, Jiaying Bai, Jing Yan, Cuiling Liu, Binbin Li   +6 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A Comparative Study of Endoscopic Ultrasound Fine-Needle Aspiration (EUS-FNA) and Endoscopic Retrograde Cholangiopancreatography (ERCP)-Based Brush Cytology for Tissue Diagnosis in Malignant Biliary Obstruction. [PDF]

Cureus, 2022
Mathew P, Kanni P, Gowda M, Devarapu C, Ansari J, Garg A.   +5 more
europepmc   +1 more source

Utility of the AVISE Connective Tissue Disease test in predicting lupus diagnosis and progression [PDF]

, 2020
Emily C. Liang, Mihaela Taylor, Maureen McMahon   +2 more
openalex   +1 more source

Automatic Diagnosis of Breast Tissue

, 2012
سيتم تعيينها حسب التكنولوجيا اعتمادًا على معيار الحافة، لحل مشاكل التجزئة مثل الضوضاء والانقطاعات (أوشر وفيدكيو، 2002). ومع ذلك، فإن جودة الثدي تجعل التجزئة فعالة فقط من خلال أخذ كل من الجوانب داخل المنطقة وفيما بين المناطق في الاعتبار. لتحقيق هدفنا وهو تجزئة العائد على الاستثمار في صور التصوير الشعاعي للثدي، نطبق طريقة مجموعة المستوى بناءً على الوظيفة
Atef Boujelben, Hedi Tmar, Mohamed Abid, J. Mnif   +3 more
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Tissue PCR Diagnosis of Patients Suspicious for Tuberculous Pleurisy [PDF]

Iranian Journal of Basic Medical Sciences, 2009
Objective(s)This study planned to assess the value of PCR IS6110 assay in tissue specimens of needle pleural biopsy inpatients suspicious to pleural tuberculosis.Materials and MethodsSixty eight patients with lymphocytic exudative pleural effusion ...
Mahnaz Amini, Davood Attaran, Kiarash Ghazvini, Habibollah Esmaily, Mahmood Bagheri   +4 more
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source