Results 121 to 130 of about 2,261,601 (352)

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Diagnosis of rectal cancer by Tissue Resonance Interaction Method

open access: yesBMC Gastroenterology, 2010
Background Since population screening has the potential to reduce mortality from rectal cancer (RC), novel methods with improved cost-effectiveness warrant consideration.
Poiasina Elia   +3 more
doaj   +1 more source

Ovarian teratoma in the mare: a review and two cases [PDF]

open access: yes, 2010
A 4-year-old Belgian Warmblood mare suffering from pelvic flexure impaction was diagnosed with a teratoma of the left ovary. The enlarged ovary was identified several days after treatment of the impaction.
de Kruif, Aart   +10 more
core  

Two-Stage Convolutional Neural Network for Breast Cancer Histology Image Classification

open access: yes, 2018
This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.
DC Cireşan   +7 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

A practical risk stratification system based on ultrasonography and clinical characteristics for predicting the malignancy of soft tissue masses

open access: yesInsights into Imaging
Objective To establish a practical risk stratification system (RSS) based on ultrasonography (US) and clinical characteristics for predicting soft tissue masses (STMs) malignancy.
Ying-Lun Zhang   +13 more
doaj   +1 more source

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