Results 31 to 40 of about 1,553,407 (312)
The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urine [PDF]
, 2010 <p><b>Background:</b>
Microseminoprotein-beta (MSMB) regulates apoptosis and using genome-wide association studies the rs10993994 single nucleotide polymorphism in the MSMB promoter has been linked to an increased risk of developing ...Page Elizabeth, Donaldson, A., Mitra, A, Stapleton, A., Donaldson, Alan, Douglas, F., Douglas, F, Whitaker Hayley C., Fiona Douglas, Leongamornlert, D., Catherine Mercer, null null, Izatt Louise, Tymrakiewicz, M., Lilja, H, Jhavar, S, Whitaker, Hayley C., Vickers, A., Anne George, Walker, L, Warren, Anne Y., Stapleton, A, David E. Neal, Elizabeth Page, Izatt, Louise, Easton, D., Virginia Clowes, Hans Lilja, Leongamornlert, D, Warren Anne Y., Neal David E., Anne Y. Warren, Lindeman, Geoffrey J., Alan Donaldson, Cooper, C., IMPACT Study Steering Committee, Tucker, Kathy, Evans, DG, Bancroft, E., Whitaker, HC, Blanco, I, Stapleton, Alan, Eeles, Rosalind, Easton, Douglas, Hodgson Shirley, Neal, David E., Blanco, I., Jimmy Lam, Lindeman, G.J., Leongamornlert Daniel, Geoffrey J. Lindeman, Tobias, E.S., Mercer, C, Leongamornlert, Daniel, Saunders, Edward, Lam, Jimmy, Izatt, L, Kirk, J, Clowes, V., Hodgson, Shirley, Douglas Easton, Daniel Leongamornlert, Rubinstein, W.S., Shirley Hodgson, David E Neal, Lisa Walker, Mitchell, G., Kirk, Judy, Ignacio Blanco, Donaldson, A, George, Anne, Eeles, R., D Gareth Evans, Neal, DE, Elizabeth Bancroft, Dorkins, H, Ross-Adams, Helen, Evans, D. Gareth; id_orcid, Bancroft, E, Gillian Mitchell, Rubinstein, WS, Bancroft Elizabeth, Donaldson Alan, Lam, J., Lindeman, GJ, Page, Elizabeth, Ross-Adams, H., Male, A, Kote-Jarai Zsofia, Bancroft, Elizabeth K., George, A., Saunders, E, Tucker Kathy, Saunders, E., Cooper Colin, Huw Dorkins, UK GPCS Collaborators, Tymrakiewicz, M, Walker Lisa, Kote-Jarai, Z., Evans, D. Gareth, Burge, Johanna, Walker, Lisa, Lilja Hans, Clowes Virginia, Rubinstein Wendy S., Evans D. Gareth, Mercer, C., Eeles Rosalind, Burge, J, Page, E, Bancroft, Elizabeth, Ross-Adams, H, Judy Kirk, Hayley C. Whitaker, Dorkins, H., Warren, A.Y., Page, E., Lilja, Hans, Anne Y Warren, Colin Cooper, Rosalind Eeles, D. Gareth Evans, Burge Johanna, Dorkins, Huw, Mitchell Gillian, Lindeman Geoffrey J., Evans, D.G., Anita Mitra, Wendy S Rubinstein, Mercer Catherine, Eeles, R, Geoffrey J Lindeman, Lilja, H., Ross-Adams Helen, Stapleton Alan, Rubinstein, Wendy S., Mitra, A., Hodgson, S., Neal, D.E., Easton, D, Jhavar, S., Alan Stapleton, Mitchell, G, Male, Alison, George Anne, Cooper, C, Wendy S. Rubinstein, Edward Saunders, Jhavar Sameer, Hodgson, S, Cooper, Colin, Helen Ross-Adams, Louise Izatt, Kote-Jarai, Zsofia, Blanco Guillermo, Ignacio, Tucker, K., Male Alison, Malgorzata Tymrakiewicz, Kote-Jarai, Z, Blanco, Ignacio, Saunders, Edward J., Evans, D. G., Johanna Burge, Tucker, K, Saunders Edward, Dorkins Huw, Tymrakiewicz, Malgorzata, Kirk, J., Mitra, Anita, Jhavar, Sameer, Blanco Ignacio, Douglas, Fiona, Mitchell, Gillian, Whitaker, H.C., Male, A., IMPACT Study Collaborators, Alison Male, Sameer Jhavar, Clowes, Virginia, Hayley C Whitaker, Tymrakiewicz Malgorzata, Warren, AY, Kathy Tucker, Zsofia Kote-Jarai, Mitra Anita, Kirk Judy, Mercer, Catherine, Lam, J, George, A, Douglas Fiona, Burge, J., Easton Douglas, Clowes, V, Lam Jimmy, Walker, L., Whitaker, H. C., Izatt, L. +197 morecore +1 more sourceRole of human tissue kallikrein in gastrointestinal stromal tumour invasion [PDF]
, 2010 Background:
Human tissue kallikrein (hK1) generates vasodilator kinins from kininogen and promotes angiogenesis by kinin-dependent and kinin-independent mechanisms.Sharman, JA, Mangialardi, GMVU, Sharman, J.A., J A Sharman, Pignatelli, M., Campagnolo, P., H. Zadeh M, P Dominek, Spinetti G, Kränkel, N, Madeddu, P, Kränkel N, H-Zadeh, M., Emanueli, C., M Pignatelli, Spinetti, G., M Chilosi, H-Zadeh, M, A Caporali, Campagnolo P, Dominek, P., Pignatelli M, P Madeddu, Mangialardi G, M H-Zadeh, Emanueli C, N Kränkel, Caporali, A, Pignatelli, M, Spinetti, G, Madeddu, P., Chilosi, M., Mangialardi, G, Emanueli, C, Dominek, PK, Kraenkel, N, Sharman, J A, G Mangialardi, Caporali A, Dominek P, Sharman JA, Madeddu, PR, Mangialardi, G., CHILOSI, Marco, P Campagnolo, Chilosi, M, G Spinetti, Campagnolo, P, Madeddu P., Kränkel, N., C Emanueli, Caporali, A., Caporali, A; id_orcid, Dominek, P +53 morecore +1 more sourceIn vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers
Genome Medicine, 2021 Background Mutations in the DMD gene encoding dystrophin—a critical structural element in muscle cells—cause Duchenne muscular dystrophy (DMD), which is the most common fatal genetic disease.Menglong Chen, Hui Shi, Shixue Gou, Xiaomin Wang, Lei Li, Qin Jin, Han Wu, Huili Zhang, Yaqin Li, Liang Wang, Huan Li, Jinfu Lin, Wenjing Guo, Zhiwu Jiang, Xiaoyu Yang, Anding Xu, Yuling Zhu, Cheng Zhang, Liangxue Lai, Xiaoping Li +19 moredoaj +1 more sourceAptamer Detection of Mycobaterium tuberculosis Mannose-Capped Lipoarabinomannan in Lesion Tissues for Tuberculosis Diagnosis
Frontiers in Cellular and Infection Microbiology, 2021 Tuberculosis (TB) is the leading infectious cause of mortality worldwide. However, the diagnosis of TB, especially extrapulmonary TB (EPTB) diagnosis from lesion tissues, remains a challenge.Yuanyuan Zhou, Yuanyuan Zhou, Yuanyuan Zhou, Huan Xiong, Huan Xiong, Huan Xiong, Rong Chen, Rong Chen, Lixia Wan, Lixia Wan, Ying Kong, Ying Kong, Ying Kong, Jianwei Rao, Jianwei Rao, Jianwei Rao, Yan Xie, Yan Xie, Yan Xie, Chaolin Huang, Chaolin Huang, Xiao-Lian Zhang, Xiao-Lian Zhang, Xiao-Lian Zhang +23 moredoaj +1 more sourceDetermination of Pericardial Adipose Tissue Increases the Prognostic Accuracy of Coronary Artery Calcification for Future Cardiovascular Events [PDF]
, 2012 Objectives: Pericardial adipose tissue (PAT) is associated with coronary artery plaque accumulation and the incidence of coronary heart disease. We evaluated the possible incremental prognostic value of PAT for future cardiovascular events.Ziegler, Franz von, Saam, Tobias, Steinbeck, Gerhard, Becker, Alexander, Hacker, Marcus, Greif, Martin, Leber, Alexander Wolfgang, Uebleis, Christopher, Rümmler, Janine, Arias-Herrera, Vivian, Becker, Christoph, D'Anastasi, Melvin +11 morecore +1 more sourceCarcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations
Pediatric Blood &Cancer, EarlyView.ABSTRACT
Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach +19 morewiley +1 more sourceEuropean Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents
Pediatric Blood &Cancer, EarlyView.ABSTRACT
Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach +23 morewiley +1 more sourceHealth‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams +8 morewiley +1 more source
