Results 41 to 50 of about 5,346,855 (293)

Spatial distribution of Mycobacterium ulcerans in Buruli ulcer lesions: implications for laboratory diagnosis [PDF]

, 2016
BACKGROUND: Current laboratory diagnosis of Buruli ulcer (BU) is based on microscopic detection of acid fast bacilli, quantitative real-time PCR (qPCR), histopathology or cultivation.
Miriam Bolz, Yeboah-Manu, Dorothy, Gerd Pluschke, Alphonse Um Boock (267187), Marie-Thérèse Ruf, Dorothy Yeboah-Manu (120059), Ruf, Marie-Thérèse, Vogel, Moritz, Um Boock, Alphonse, Pierre F. Bayi (2814127), Marie-Thérèse Ruf (2280196), Martin W. Bratschi (309715), Moritz Vogel, Ghislain Emmanuel Sopho, Moritz Vogel (267190), Bayi, Pierre F., Bolz, Miriam, Thomas Junghanss, Miriam Bolz (309717), Alphonse Um Boock, Bratschi, Martin W., Gerd Pluschke (7855), Sopho, Ghislain Emmanuel, Thomas Junghanss (46932), Martin W Bratschi, Dorothy Yeboah-Manu, Pierre F Bayi, Junghanss, Thomas, Ghislain Emmanuel Sopho (2814130), Pluschke, Gerd   +29 more
core   +2 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Directly anterior approach for total hip arthroplasty with an acetabular structural bone graft for developmental dysplasia of the hip (Crowe III and IV): a concise 5-year follow-up evaluation

BMC Musculoskeletal Disorders
Background This study evaluated the results of total hip arthroplasty (THA) via the direct anterior approach (DAA) in the lateral decubitus position combined with acetabular reconstruction via a bulk autograft for patients with developmental dysplasia of
Lijia Pei, Ben Liu, Yifan Wu, Yuanhang Wang, Wenhao Sun, Wenju Chang, Xinshe Zhou   +6 more
doaj   +1 more source

Imprint cytology: A boon in tissue diagnosis

Medical Journal of Dr. D.Y. Patil University, 2017
Background: The technique of imprint cytology has provided great impetus to cytodiagnosis due to its simplicity, cost effectiveness, rapid results. It plays a significant role in the rapid diagnosis of the lesions.
Charusheela Rajesh Gore, Bikash K Singh, Shirish S Chandanwale, Sushma G Gurwale, Harsh Kumar, Rupali Bawikar, Indranil Dey   +6 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

Isolation and characterization of human cKIT positive amniotic fluid stem cells obtained from pregnancies with spina bifida

Scientific Reports
Myelomeningocele (MMC) and myeloschisis (MS) are considered as the most severe forms of spina bifida aperta characterized by incomplete closure of the neural tube during the first trimester of pregnancy. Open maternal-fetal surgery has been identified as
Katarzyna Michalak-Micka, Nadine Huerlimann, Nicole Ochsenbein-Kölble, Martin Ehrbar, Agnes Silvia Klar, Thomas Biedermann, Ueli Moehrlen   +6 more
doaj   +1 more source

Adipose derived tissue engineered heart valve [PDF]

, 2015
Introduction: A major challenge associated with heart valve tissue engineering is the in vitro creation of mature tissue structures compliant with native valve functionality.
Baaijens, FPT Frank, Beer, G M, Driessen - Mol, A., Hoerstrup, S., Beer, G.M., Baaijens, Frank P T, Baaijens, F.P.T., Weber, B., Hoerstrup, S P, Driessen-Mol, Anita, Frese, Laura, Frese, L., Driessen-Mol, A Anita, Weber, Benedikt, Beer, Gertrude M, Sanders, B Bart, Hoerstrup, S Simon, Sanders, Bart, Sanders, B.   +18 more
core   +2 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

A recurrent OKC infected with actinomyces

BMC Oral Health
Background The postoperative recurrence of mandibular odontogenic keratocyst (OKC) accompanied by secondary actinomycotic osteomyelitis is extremely rare and presents significant challenges in clinical diagnosis and treatment.
Yuxin Ma, Lin Yang, Bao Zhong, Jingchao Han   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source