Results 51 to 60 of about 1,553,407 (312)

Urinary proteomics to support diagnosis of stroke [PDF]

, 2012
Accurate diagnosis in suspected ischaemic stroke can be difficult. We explored the urinary proteome in patients with stroke (n = 69), compared to controls (n = 33), and developed a biomarker model for the diagnosis of stroke.
Mischak, H., Delles Christian, Dawson Jesse, Dawson, J., Mullen, W., Jesse Dawson, William Mullen, Delles, C., Walters Matthew, Mullen William, Matthew Walters, Harald Mischak, Walters, M., Christian Delles, Mischak Harald   +14 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Directly anterior approach for total hip arthroplasty with an acetabular structural bone graft for developmental dysplasia of the hip (Crowe III and IV): a concise 5-year follow-up evaluation

BMC Musculoskeletal Disorders
Background This study evaluated the results of total hip arthroplasty (THA) via the direct anterior approach (DAA) in the lateral decubitus position combined with acetabular reconstruction via a bulk autograft for patients with developmental dysplasia of
Lijia Pei, Ben Liu, Yifan Wu, Yuanhang Wang, Wenhao Sun, Wenju Chang, Xinshe Zhou   +6 more
doaj   +1 more source

Improving the Diagnosis of Skin Biopsies Using Tissue Segmentation

Diagnostics, 2022
Invasive melanoma, a common type of skin cancer, is considered one of the deadliest. Pathologists routinely evaluate melanocytic lesions to determine the amount of atypia, and if the lesion represents an invasive melanoma, its stage.
Shima Nofallah, Beibin Li, Mojgan Mokhtari, Wenjun Wu, Stevan Knezevich, Caitlin J. May, Oliver H. Chang, Joann G. Elmore, Linda G. Shapiro   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Isolation and characterization of human cKIT positive amniotic fluid stem cells obtained from pregnancies with spina bifida

Scientific Reports
Myelomeningocele (MMC) and myeloschisis (MS) are considered as the most severe forms of spina bifida aperta characterized by incomplete closure of the neural tube during the first trimester of pregnancy. Open maternal-fetal surgery has been identified as
Katarzyna Michalak-Micka, Nadine Huerlimann, Nicole Ochsenbein-Kölble, Martin Ehrbar, Agnes Silvia Klar, Thomas Biedermann, Ueli Moehrlen   +6 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

A recurrent OKC infected with actinomyces

BMC Oral Health
Background The postoperative recurrence of mandibular odontogenic keratocyst (OKC) accompanied by secondary actinomycotic osteomyelitis is extremely rare and presents significant challenges in clinical diagnosis and treatment.
Yuxin Ma, Lin Yang, Bao Zhong, Jingchao Han   +3 more
doaj   +1 more source

Optimisation of machine learning methods for cancer detection using vibrational spectroscopy [PDF]

, 2011
Early cancer detection drastically improves the chances of cure and therefore methods are required, which allow early detection and screening in a fast, reliable and inexpensive manner.
Sattlecker, Martine
core  

Artificial neural networks in hard tissue engineering : another look at age-dependence of trabecular bone properties in osteoarthritis [PDF]

, 2014
Artificial Neural Network (ANN) model has been developed to correlate age of severely osteoarthritic male and female specimens with key mechanical and structural characteristics of their trabecular bone.
Natasha A Khovanova, Khovanova, N. A., Mallick, Kajal, Shaikhina, Torgyn, Torgyn Shaikhina, Kajal K Mallick   +5 more
core   +1 more source