Results 51 to 60 of about 5,346,855 (293)

Impeding glial scarring hyperplasia and activating axon neogenesis via immunomodulatory microneedle patch for spinal cord repair

Journal of Nanobiotechnology
Immune dysregulation and scar tissue formation following traumatic spinal cord injury (SCI) result in the generation of a microenvironment that significantly inhibits nerve regeneration and functional recovery.
Tao Zhou, Yajing Lin, Ying Wang, Lin Lin, Jingtong Li, Ning Tang, Yingji Mao, Pinghui Zhou   +7 more
doaj   +1 more source

Comparison of quantitative real time PCR with Sequencing and ribosomal RNA-FISH for the identification of fungi in Formalin fixed, paraffin-embedded tissue specimens [PDF]

, 2011
Background: Identification of the causative agents of invasive fungal infections (IFI) is critical for guiding antifungal therapy. Cultures remain negative in a substantial number of IFI cases.
Rickerts Volker, Ko Daisy L, Fredricks, David N., Prasanna D Khot, David N Fredricks, David Myerson, Khot Prasanna D, Myerson David, Ko, Daisy L., Khot, Prasanna D., Myerson, David, Volker Rickerts, Lambrecht, Evelyn, Lambrecht Evelyn, Rickerts, Volker, Fredricks David N, Daisy L Ko, Evelyn Lambrecht   +17 more
core   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Role of fine-needle aspiration cytology in evaluating mediastinal masses

Lung India, 2009
Background: Fine-needle aspiration cytology is an important and useful investigation and is considered next to imaging in the diagnosis of mediastinal lesions.
Pandey D, Ahmad Zuber, Masood I, Singh S, Jairajpuri Z   +4 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Preoperative tissue diagnosis for tumours of the pancreas

Journal of British Surgery, 2009
Abstract Background Preoperative biopsy of pancreatic lesions suspected of malignancy is controversial. Methods A systematic Medline literature search was carried out.
W, Hartwig, L, Schneider, M K, Diener, F, Bergmann, M W, Büchler, J, Werner   +5 more
openaire   +2 more sources

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Cancer-associated fibroblast-induced lncRNA WARS2-IT1 confers radioresistance of colorectal cancer via enhancing HIF-1α stability

Cell Death and Disease
The tumor microenvironment in colorectal cancer (CRC) is marked by a diverse and abundant population of cancer-associated fibroblasts (CAFs), which play a crucial role in radioresistance.
Yuanqi Li, Wei Dai, Xiao Zheng, Qi Wang, Jinping Zhang, Xiangyin Kong, Jingting Jiang, You Zhou   +7 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

MXenes‐based flexible electronics for wound monitoring and treatment

Interdisciplinary Medicine
Wound healing is a dynamic and overlapping bio‐process with varied cellular and molecular characteristics involved. Traditional wound dressings have made significant achievements in accelerating wound healing; however, they lack the ability to monitor ...
Ye Yang, Zesheng Chen, Wenwen Cheng, Fanghan Li, Xiaolong Wang, Zijian Wang, Weikang Hu   +6 more
doaj   +1 more source