Plasma Bead Entrapped Liposomes as a Potential Drug Delivery System to Combat Fungal Infections
Fibrin-based systems offer promises in drug and gene delivery as well as tissue engineering. We established earlier a fibrin-based plasma beads (PB) system as an efficient carrier of drugs and antigens.
Munazza Tamkeen Fatima +4 more
doaj +1 more source
Involvement of UDP-Glucuronosyltransferases and Sulfotransferases in the Excretion and Tissue Distribution of Resveratrol in Mice. [PDF]
Resveratrol is a naturally occurring polyphenolic compound with various pharmacological activities. It is unknown whether the expression of metabolizing enzymes correlates with resveratrol levels in organs and tissues.
Brenner, Stefan +8 more
core +2 more sources
Leptin: its pharmacokinetics and tissue distribution [PDF]
The pharmacokinetics and tissue distribution of leptin in rats was investigated.A catheter was inserted in the right jugular vein of rats on the day prior to experiment. The next day, blood was sampled and then a tracer dose of radioiodinated hormone was administered via the catheter.
Hill, Rodney +3 more
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Reentry near the percolation threshold in a heterogeneous discrete model for cardiac tissue [PDF]
Arrhythmias in cardiac tissue are related to irregular electrical wave propagation in the heart. Cardiac tissue is formed by a discrete cell network, which is often heterogeneous.
Alonso Muñoz, Sergio, Baer, Markus
core +2 more sources
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. [PDF]
Two different monoclonal antibodies, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton protein, which is exposed on the outer surface of brain synaptic vesicles. Immunocytochemical experiments at the electron
Matthew, WD, Reichardt, LF, Tsavaler, L
core +2 more sources
DISTRIBUTION OF ZINC IN BONE TISSUE [PDF]
High concentrations of zinc have been found by a histochemical method at the sites of calcification. Zinc has been detected in the developing osteons (Haversian systems) of compact bone exactly at the border line between calcified and uncalcified tissue (Fig. 1), in the cartilaginous partitions of hypertrophic cells (Fig.
openaire +2 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Physiological Functions and Molecular Mechanisms of Neurokinin B in Fish
Neurokinin B (NKB) is a hypothalamic neuropeptide containing 10 amino acids and is an essential member of the tachykinin family. Based on studies in mammals, Kiss, NKB, and dynorphin A are located in the common neurons, named KNDy neurons, and NKB and ...
Bin WANG +5 more
doaj +1 more source

