Results 71 to 80 of about 8,279,566 (317)
THE DISTRIBUTION OF METABOLITES IN THE BLOOD AND TISSUES [PDF]
Archives of Internal Medicine, 1922 INTRODUCTION With the introduction of simple and reliable microchemical methods of analysis, the determination of the concentration of metabolites in the blood has become an accepted clinical procedure. Consequently, the relation of metabolites in the blood to their distribution throughout the entire organism is a subject of clinical as well as ...
openaire +2 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Frontiers in Pharmacology, 2017 The mechanisms underlying the enhancement of insulin sensitivity by selective peroxisome proliferator-activated receptor γ modulators (sPPARγMs) are still not completely known.
Xinni Xie +15 more
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PEPTIDASE DISTRIBUTION IN LYMPHATIC TISSUE [PDF]
The Journal of Cell Biology, 1955 The lymphatic tissue of the rabbit contains a labile peptidase as measured by the hydrolysis of alanylglycine. Some characteristics of the enzyme were determined. This enzyme increases in amount when the numbers of macrophages in the tissue are increased and it is also present in the extracellular fluid in high concentration.
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Tissue distribution in male and female.
, 2013 Tissue distribution in male and female.
Walter S. Leal (104796) +3 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Subchronic inhalation toxicity of gold nanoparticles
Particle and Fibre Toxicology, 2011 Background Gold nanoparticles are widely used in consumer products, including cosmetics, food packaging, beverages, toothpaste, automobiles, and lubricants.
Chung Yong +15 more
doaj +1 more source
Tissue Distribution of 212Bi in Rats
Experimental Biology and Medicine, 1969 SummaryThe 212Bi, relatively free of its parent 212Pb was injected intravenously into rats and the tissue distribution and was followed for a period of 2 hr postinjection. The kidney contained the highest concentration, equal to about 10 times that of the liver and spleen.
J B, Hursh, C, Brown
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PP2A B’’-subunits and their tissue distribution.
, 2014 PP2A B’’-subunits and their tissue distribution.
Pär Nordlund (161768) +5 more
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source