Results 61 to 70 of about 3,131,990 (302)

On the role of specific drug binding in modelling arterial eluting stents [PDF]

open access: yes, 2016
In this paper we consider drug binding in the arterial wall following delivery by a drug-eluting stent. Whilst it is now generally accepted that a non-linear saturable reversible binding model is required to properly describe the binding process, the ...
AR Tzafriri   +13 more
core   +1 more source

PEPTIDASE DISTRIBUTION IN LYMPHATIC TISSUE [PDF]

open access: yesThe Journal of Cell Biology, 1955
The lymphatic tissue of the rabbit contains a labile peptidase as measured by the hydrolysis of alanylglycine. Some characteristics of the enzyme were determined. This enzyme increases in amount when the numbers of macrophages in the tissue are increased and it is also present in the extracellular fluid in high concentration.
openaire   +2 more sources

Bioadditive manufacturing of hybrid tissue scaffolds for controlled release kinetics [PDF]

open access: yes, 2012
Development of engineered tissue scaffolds with superior control over cell-protein interactions is still very much infancy. Advancing through heterogeneous multifold scaffolds with controlled release fashion enables synchronization of regenerating tissue
Khoda, AKMB   +2 more
core   +1 more source

Tissue Distribution of 212Bi in Rats

open access: yesExperimental Biology and Medicine, 1969
SummaryThe 212Bi, relatively free of its parent 212Pb was injected intravenously into rats and the tissue distribution and was followed for a period of 2 hr postinjection. The kidney contained the highest concentration, equal to about 10 times that of the liver and spleen.
J B, Hursh, C, Brown
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Study on Formulation, in vivo Exposure, and Passive Targeting of Intravenous Itraconazole Nanosuspensions

open access: yesFrontiers in Pharmacology, 2019
The pharmacokinetic profile of a drug can be different when delivered as a nanosuspension compared with a true solution, which may in turn affect the therapeutic effect of the drug.
Qi Yuan   +9 more
doaj   +1 more source

Pharmacokinetic herb-drug interactions: Altered systemic exposure and tissue distribution of ciprofloxacin, a substrate of multiple transporters, after combined treatment with Polygonum capitatum Buch.-Ham. ex D. Don extracts

open access: yesFrontiers in Pharmacology, 2022
Background: Combination of Polygonum capitatum Buch.-Ham. ex D. Don extract (PCE) and ciprofloxacin (CIP) was commonly prescribed in the treatment of urinary tract infections. Their pharmacokinetic herb-drug interactions (HDIs) were focused in this study
Ziqiang Li   +8 more
doaj   +1 more source

Thyroid hormone receptors and ligand, tissue distribution and sexual behavior [PDF]

open access: yes, 2018
The thyroid hormones (THs) triiodothyronine (T3) and tetraiodothyronine, or thyroxine (T4), not only dramatically impact on development and differentiation, but also on the sexual and reproductive function.
Carosa, E, Jannini, Ea, Lenzi, A
core   +1 more source

Clinical Insights Into Hypercalcemia of Malignancy in Childhood

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley   +1 more source

New Insights Into the Evolution of Corticotropin-Releasing Hormone Family With a Special Focus on Teleosts

open access: yesFrontiers in Endocrinology, 2022
Corticotropin-releasing hormone (CRH) was discovered for its role as a brain neurohormone controlling the corticotropic axis in vertebrates. An additional crh gene, crh2, paralog of crh (crh1), and likely resulting from the second round (2R) of ...
Gersende Maugars   +6 more
doaj   +1 more source

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