Results 41 to 50 of about 3,131,990 (302)

Tissue Distributions and Toxic Effects of Hexavalent Chromium in Laboratory-Exposed Periwinkle (Littorina littorea Linnaeus)

Animals, 2023
The increased use of hexavalent chromium (Cr6+) in various industrial applications has contributed to its elevated levels in the environment, especially the aquatic environment.
Olufemi S. Salami, Joseph A. Adeyemi, Toluwase S. Olawuyi, Fernando Barbosa, Chris O. Adedire   +4 more
doaj   +1 more source

Pharmacokinetics and tissue distribution of four major bioactive components of Cynanchum auriculatum extract: a UPLC–MS/MS study in normal and functional dyspepsia rats

Frontiers in Pharmacology, 2023
Introduction:Cynanchum auriculatum (CA) is usually used to treat digestive disorders, such as anorexia, enteritis, dysentery, and indigestion. Functional dyspepsia (FD) is characterized by a group of symptoms associated with the gastroduodenal region ...
Jia Sun, Jia Sun, Xin Meng, Xin Meng, Di Huang, Di Huang, Zipeng Gong, Chunhua Liu, Ting Liu, Jie Pan, Yuan Lu, Lin Zheng   +11 more
doaj   +1 more source

DISTRIBUTION OF PROSTAGLANDINS IN HUMAN TISSUES [PDF]

British Journal of Pharmacology and Chemotherapy, 1967
The concentrations of prostaglandins present in 23 types of human tissues was estimated. Tissues were obtained from necropsy examinations of adult patients carried out within 24 hours. All tissues were macroscopically free of disease and in most instances were examined histologically to confirm this. The preparation used was shown to be sensitive to
S M, Karim, M, Sandler, E D, Williams
openaire   +2 more sources

Absolute Bioavailability, Tissue Distribution, and Excretion of Erinacine S in Hericium erinaceus Mycelia

Molecules, 2019
Erinacine S, so far known to have been produced only in Hericium erinaceus mycelia, has just recently been discovered and is able to reduce amyloid plaque growth and improve neurogenesis in aged brain of rats.
Jun-Hao Hu, I-Chen Li, Ting-Wei Lin, Wan-Ping Chen, Li-Ya Lee, Chin-Chu Chen, Chia-Feng Kuo   +6 more
doaj   +1 more source

Analysis of healthy sitting behavior: Interface pressure distribution and subcutaneous tissue oxygenation [PDF]

, 2009
Pressure ulcers are a large problem in individuals who use a wheelchair for their mobility and have limited trunk stability and motor function. Because no relation between interface pressure and pressure ulcer development has been established and no ...
Geffen, Paul van, IJzerman, Maarten, Jannink, Michiel, Nederhand, Marc, Reenalda, Jasper, Rietman, Hans   +5 more
core   +2 more sources

Ethnic differences in adiposity and diabetes risk – insights from genetic studies [PDF]

, 2020
Type 2 diabetes is more common in non-Europeans and starts at a younger age and at lower BMI cut-offs. This review discusses the insights from genetic studies about pathophysiological mechanisms which determine risk of disease with a focus on the role of
Bell, J.D., Bell, J.D., Thomas, E.L., Thomas, E.L., Whitcher, B., Whitcher, B., Yaghootkar, H., Yaghootkar, H.   +7 more
core   +2 more sources

Pharmacokinetics, Tissue Distribution, and Elimination of Three Active Alkaloids in Rats after Oral Administration of the Effective Fraction of Alkaloids from Ramulus Mori, an Innovative Hypoglycemic Agent

Molecules, 2017
In this study, we systematically investigated the plasma pharmacokinetics, tissue distribution, and elimination of three active alkaloids after oral administration of the effective fraction of alkaloids from Ramulus Mori (SZ–A)—an innovative hypoglycemic
Shuang Yang, Jiaqi Mi, Zhihao Liu, Baolian Wang, Xuejun Xia, Renyun Wang, Yuling Liu, Yan Li   +7 more
doaj   +1 more source

Absorption, tissue distribution, and excretion of glycycoumarin, a major bioactive coumarin from Chinese licorice (Glycyrrhiza uralensis Fisch)

Frontiers in Pharmacology, 2023
Licorice (Glycyrrhiza uralensis Fisch) is a natural plant resource widely used as a food and herbal medication in China. Glycycoumarin (GCM) is a major coumarin in licorice that possesses several biological activities.
Linhu Ye, Linhu Ye, Linhu Ye, Lei Cheng, Yan Deng, Sen Wang, Xinyu Wu, Shuiping Ou, Qi Chang, Xinqian Zhao, Wen Zhou, Jinghua Yu, Zuqiang Wu   +12 more
doaj   +1 more source

Expression Patterns of PACAP and PAC1R Genes and Anorexigenic Action of PACAP1 and PACAP2 in Zebrafish

Frontiers in Endocrinology, 2019
Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide with potent suppressive effects on feeding behavior in rodents, chicken, and goldfish. Teleost fish express two PACAPs (PACAP1, encoded by the adcyap1a gene, and PACAP2, encoded
Tomoya Nakamachi, Ayano Tanigawa, Norifumi Konno, Seiji Shioda, Kouhei Matsuda   +4 more
doaj   +1 more source

Change of metformin concentrations in the liver as a pharmacological target site of metformin after long-term combined treatment with ginseng berry extract

Frontiers in Pharmacology, 2023
Metformin as an oral glucose-lowering drug is used to treat type 2 diabetic mellitus. Considering the relatively high incidence of cardiovascular complications and other metabolic diseases in diabetic mellitus patients, a combination of metformin plus ...
Choong Whan Lee, Byoung Hoon You, Sreymom Yim, Seung Yon Han, Hee-Sung Chae, Hee-Sung Chae, Mingoo Bae, Seo-Yeon Kim, Jeong-Eun Yu, Jieun Jung, Piseth Nhoek, Hojun Kim, Han Seok Choi, Young-Won Chin, Hyun Woo Kim, Young Hee Choi   +15 more
doaj   +1 more source