Results 31 to 40 of about 3,131,990 (302)

Improved Pharmacokinetic Feasibilities of Mirabegron-1,2-Ethanedisulfonic Acid, Mirabegron-1,5-Naphthalenedisulfonic Acid, and Mirabegron-L-Pyroglutamic Acid as Co-Amorphous Dispersions in Rats and Mice

open access: yesPharmaceutics, 2023
Mirabegron (MBR) is a β3-adrenoceptor agonist used for treating overactive bladder syndrome. Due to its poor solubility and low bioavailability (F), the development of novel MBR formulations has garnered increasing attention.
Seo-Yeon Kim   +5 more
doaj   +1 more source

DISTRIBUTION OF ZINC IN BONE TISSUE [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1961
High concentrations of zinc have been found by a histochemical method at the sites of calcification. Zinc has been detected in the developing osteons (Haversian systems) of compact bone exactly at the border line between calcified and uncalcified tissue (Fig. 1), in the cartilaginous partitions of hypertrophic cells (Fig.
openaire   +2 more sources

Reentry near the percolation threshold in a heterogeneous discrete model for cardiac tissue [PDF]

open access: yes, 2013
Arrhythmias in cardiac tissue are related to irregular electrical wave propagation in the heart. Cardiac tissue is formed by a discrete cell network, which is often heterogeneous.
Alonso Muñoz, Sergio, Baer, Markus
core   +2 more sources

Analysis of the Distribution of Total Phosphine and the Characteristics of Phosphine Poisoning in 29 Victims

open access: yesFayixue Zazhi, 2022
ObjectiveTo study the distribution of total phosphine in phosphine poisoning victims and summarize the characteristics of phosphine poisoning cases.MethodsThe phosphine and its metabolites in the biological samples of 29 victims in 16 phosphine poisoning
YAN Hui   +6 more
doaj   +1 more source

Perivascular adipose tissue as a relevant fat depot for cardiovascular risk in obesity [PDF]

open access: yes, 2018
Obesity is associated with increased risk of premature death, morbidity, and mortality from several cardiovascular diseases (CVDs), including stroke, coronary heart disease (CHD), myocardial infarction, and congestive heart failure.
Costa, Rafael M.   +3 more
core   +3 more sources

Distribution of Micro-Nano PS, DEHP, and/or MEHP in Mice and Nerve Cell Models In Vitro after Exposure to Micro-Nano PS and DEHP

open access: yesToxics, 2023
Polystyrene (PS) and di-(2-ethylhexyl) phthalate (DEHP) exist widely in the environment. However, their distribution in organisms remains unclear. We used three sizes (50 nm, 500 nm, and 5 μm) of PS and DEHP to study the distribution and accumulation of ...
Jie Han   +8 more
doaj   +1 more source

Adipose Tissue Distribution and Survival Among Women with Nonmetastatic Breast Cancer. [PDF]

open access: yes, 2019
ObjectivePrevious studies of breast cancer survival have not considered specific depots of adipose tissue such as subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT).MethodsThis study assessed these relationships among 3,235 women with ...
Albers, Kathleen B   +6 more
core   +2 more sources

Dynamic Distribution of Mesanophrys sp. and Tissue Enzyme Activities in Experimentally Infected Mud Crab Scylla paramamosain

open access: yesFishes, 2023
Mesanophrys sp. is reported to be highly pathogenic to marine crustaceans. This study presents the first report of Mesanophrys sp. infection in the mud crab (Scylla paramamosain).
Kexin Zhang   +9 more
doaj   +1 more source

THE DISTRIBUTION OF ESTERASES IN MOUSE TISSUES [PDF]

open access: yesJournal of Histochemistry & Cytochemistry, 1959
The esterases contained in 32 mouse tissues and organs have been analyzed using the zymogram technique. More than ten different esterases have been resolved and partly characterized by their substrate and inhibition specificities. The esterases compose a family of distinct enzymes with overlapping specificities, and the total activity in any tissue is
C L, MARKERT, R L, HUNTER
openaire   +2 more sources

Lipid changes within the epidermis of living skin equivalents observed across a time-course by MALDI-MS imaging and profiling [PDF]

open access: yes, 2015
© 2015 Mitchell et al. Abstract Background: Mass spectrometry imaging (MSI) is a powerful tool for the study of intact tissue sections. Here, its application to the study of the distribution of lipids in sections of reconstructed living skin equivalents ...
Clench, Malcolm   +4 more
core   +2 more sources

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