Results 11 to 20 of about 3,131,990 (302)
Nanomaterials, 2023 The widespread biomedical and commercial applications of silver nanoparticles (AgNPs) have increased their potential for human and environmental exposure and toxicity to human health.
Elsayed I. Salim +4 more
doaj +1 more source
Applied Sciences, 2021 Quiescin Q6 sulfhydryl oxidase 1 (QSOX1) catalyzes the oxidation of the sulfhydryl group to disulfide bond and is widely expressed in various tissues. This study focuses on investigating QSOX1′s spatiotemporal and cellular protein expression profile of ...
Hung-Shih Lin +4 more
doaj +1 more source
Molecules, 2021 Poloxamer188 (PL188), as one of the most commonly used pharmaceutical excipients, has unique physicochemical properties and good biocompatibility, and so is playing an increasingly extensive role in the field of medicine. Currently, there are few studies
Yixuan Feng +7 more
doaj +1 more source
Evaluation of the activity of cyanide-metabolizing sulfurtransferase enzymes in different tissues of turkey (Meleagris gallopavo) [PDF]
The Iranian Journal of Veterinary Science and Technology, 2015 This study was undertaken to estimate specific activities of rhodanese and 3-mercaptopyruvate sulfurtransferase (MST) in different tissues of turkey.
Kamal JalilianKabiri, Hassan Baghishani
doaj +1 more source
Optimization, and in vitro and in vivo evaluation of etomidate intravenous lipid emulsion
Drug Delivery, 2021 The aim of this investigation was to develop an etomidate intravenous lipid emulsion (ETM-ILE) and evaluate its properties in vitro and in vivo. Etomidate (ETM) is a hydrophobic drug, and organic solvents must be added to an etomidate injectable solution
Dandan Geng +8 more
doaj +1 more source
Human Tissue Distribution of Voriconazole [PDF]
Antimicrobial Agents and Chemotherapy, 2011 ABSTRACT Voriconazole concentrations were determined in autopsy samples of eight patients who had been treated for a median of 7 days (interquartile range [IQR], 5 days). Voriconazole penetrates well into various tissues, with median levels of 6.26 μg/g ((interquartile range [IQR], 7.87 μg/g) in the lung, 3.41 μg/g (IQR, 16.72 μg/g) in the ...
Stefan, Weiler +7 more
openaire +2 more sources
Computational fluid dynamic analysis of bioprinted self-supporting perfused tissue models [PDF]
, 2020 Natural tissues are incorporated with vasculature, which is further integrated with a cardiovascular system responsible for driving perfusion of nutrient‐rich oxygenated blood through the vasculature to support cell metabolism within most cell‐dense ...
Bonewald, Lynda F. +8 more
core +1 more source
Drug Delivery, 2021 Background Combination of the prodrug technique with an albumin nano drug-loaded system is a novel promising approach for cancer treatment. However, the long-lasting and far-reaching challenge for the treatment of cancers lies in how to construct the ...
Hang Chen +14 more
doaj +1 more source
Fishes, 2022 Kidney-type glutaminase, encoded by the gls1 gene, plays a critical role in glutamate production and improvement of meat flavor. In this study, a gls1 gene encoding 595 amino acids was cloned from triploid crucian carp (Carassius auratus) (TCC) and ...
Yangbo Xiao +14 more
doaj +1 more source
Human tissue distribution of caspofungin
International Journal of Antimicrobial Agents, 2022 Tissue concentrations of caspofungin were determined in nine clinically relevant tissues taken during routine autopsy of 20 patients who had died during caspofungin treatment or within 23 days of cessation. The highest levels were achieved in liver, with concentrations ranging from ≤0.50 to 91.5 µg/g (0.60 µg/g 21 days after the last administration ...
Jana Marx +7 more
openaire +2 more sources