Results 281 to 290 of about 3,009,910 (332)

Serum soluble mediator signatures of lupus nephritis: histological features and response to treatment

Arthritis Care &Research, Accepted Article.
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histological features and treatment response.
Andrea Fava, Catriona A. Wagner, Carla J. Guthridge, Susan Macwana, Wade DeJager, Melissa E. Munroe, Peter Izmirly, H. Michael Belmont, Betty Diamond, Anne Davidson, Paul J. Utz, Michael H Weisman, Philip M Carlucci, Maria Dall'Era, Kenneth Kalunian, Chaim Putterman, Jennifer Anolik, Jennifer L Barnas, David Wofsy, Diane Kamen, Richard A Furie, Deepak A Rao, the Accelerating Medicines Partnership (AMP) RA/SLE Network, Michelle Petri, Joel M. Guthridge, Jill Buyon, Judith A. James   +26 more
wiley   +1 more source

Pharmacokinetics and tissue distribution of vigabatrin enantiomers in rats. [PDF]

Saudi Pharm J
Zheng Q, He S, Xu SL, Ma MD, Fan M, Ge JF.   +5 more
europepmc   +1 more source

Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients

Arthritis Care &Research, Accepted Article.
Background Maturational signal in the sacroiliac joint (SIJ) of skeletally immature youth is often misinterpreted as inflammation. Diagnostic tools that improve specificity are greatly needed. Apparent diffusion coefficient (ADC) values from diffusion‐weighted imaging (DWI), when used with standard imaging, may enhance diagnostic accuracy.
Michael L. Francavilla, Timothy G. Brandon, Dmitry Khrichenko, Rui Xiao, Nancy A. Chauvin, Asef Khwaja, Pamela F. Weiss   +6 more
wiley   +1 more source

Pharmacokinetics and tissue distribution of LN002, a new compound alternative oxidase inhibitor against Cryptosporidium in rats. [PDF]

Front Pharmacol
Ma M, Zhang Y, Fang Y, Lu Y, Huang H, Zeng Z, Zeng D.   +6 more
europepmc   +1 more source

Association between Discordance of Disease Activity Indices and Quantitative Sensory Testing Measures of Nociplastic Pain in Patients with Rheumatoid Arthritis

Arthritis Care &Research, Accepted Article.
Objective This study investigates the association between discordance in commonly collected clinical indicators of rheumatoid arthritis (RA) disease activity and abnormalities in quantitative sensory testing (QST) observed in individuals with nociplastic pain.
Clarice P. Lin, Burcu Aydemir, Jing Song, Lutfiyya N. Muhammad, Tuhina Neogi, Wendy Marder, Clifton O. Bingham, Marcy B. Bolster, Daniel J. Clauw, Dorothy D. Dunlop, Yvonne C. Lee   +10 more
wiley   +1 more source

Characterization of Leptin and Leptin Receptor Gene in the Siberian Sturgeon (<i>Acipenser baerii</i>): Molecular Cloning, Tissue Distribution, and Its Involvement in Feeding Regulation. [PDF]

Int J Mol Sci
Wu H, Li J, Jiang K, Li Y, Yu Z, Wang B, Zhou B, Zhang X, Tang N, Li Z.   +9 more
europepmc   +1 more source

The Immobilization of Hyaluronic Acid in 3D Hydrogel Scaffolds Modulates Macrophage Polarization

Advanced Biology, EarlyView.
This study explores the use of collagen‐hyaluronic acid (HA) hydrogels for the 3D culture of macrophages, providing a useful tool for modelling macrophage behavior in tissues and diseases. It highlights how hydrogel composition, mechanical properties, and preparation methods influence macrophage behavior, revealing for the first time that HA's ...
Tiah CL Oates, Jasmin Boyd, Louise Dolan, C de Kergariou, Jingwen Zhu, Ash Toye, Adam W Perriman, Asme Boussahel   +7 more
wiley   +1 more source

LC-MS/MS assisted pharmacokinetic and tissue distribution study of ropivacaine and 3-OH-ropivacaine on rats after plane block anesthesia. [PDF]

Front Pharmacol
Butiulca M, Farczadi L, Imre S, Vari CE, Vlase L, Cordos B, Azamfirei L, Lazar AE.   +7 more
europepmc   +1 more source

Using a Supramolecular Approach to Engineer Modular Hydrogel Platforms for Culturing Protoplasts – from General Tissue Engineering to Cellular Agriculture

Advanced Biology, EarlyView.
Using supramolecular monomers, various hydrogel culture systems were formulated to culture protoplasts; including 2D, 2.5D, and 3D hydrogels. Depending on the culture platform, bioactive functionalization led to protoplast enlargement (2D and 2.5D) or plasmolysis (3D). This work shows the potential to modularly engineer synthetic platforms for cellular
Maritza M. Rovers, Erik J. Slootweg, Ferdinand C. O. Los, Patricia Y. W. Dankers   +3 more
wiley   +1 more source

Effect of caffeic acid grafted chitosan loaded quercetin lyophilized powder formulation on avian colibacillosis and tissue distribution. [PDF]

Front Vet Sci
Ren X, Yuan S, Ren J, Ma L, Liu J, Wang G.   +5 more
europepmc   +1 more source