Results 211 to 220 of about 2,247,754 (308)

Intrapancreatic fat deposition shows distinct regional and compartmental associations with obesity and diabetes. [PDF]

iScience
Adnan D, Allaoa A, Khoshaba ER, Cheng L, Bishehsari F.   +4 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Cryopreservation Maintains Structural Integrity and Biomechanical Properties of Human Rectus Fascia for up to 1 mo. [PDF]

Transplant Direct
Hennion I, Van De Winkel N, Weisrock A, Dubois A, Van Slambrouck J, Philips C, Deelkens C, Dedja K, Jin X, Barbarossa A, Muylle E, Heylen L, De Hertogh G, D'Hoore A, Pirenne J, Lagrou K, Lecomte-Grosbras P, Thorrez L, Ceulemans LJ.   +18 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Predicting Relevant Microglia-Associated Cell-Cell Communication Pathways in Alzheimer's Disease: A Role for SPP1. [PDF]

Glia
Kotah JM, Lima MT, Dragt EC, Voulgaroglou A, Brouwer N, Holtman IR, Kooistra SM, Eggen BJL.   +7 more
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Characterizing Donor-Derived Cells in Nonhematopoietic Tissue

Biology of Blood and Marrow Transplantation, 2006
Ramakrishnan, Aravind, Shi, Daqing, Torok-Storb, Beverly   +2 more
openaire   +2 more sources

Alarmins differentially modulate airway contraction and relaxation of human small airways. [PDF]

Respir Res
Kennedy JL, Frederick DN, Panettieri RA, Koziol-White CJ.   +3 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Evaluating the impact of blue-filtering intraocular lenses on macular oxidative stress: A comparative analysis of 8-hydroxy-2'-deoxyguanosine levels in the retinal tissue of donor eyes. [PDF]

Indian J Ophthalmol
Sevugamurthi K, Sivashanmugam P, Jaju S, Janani PS, Sakthivel V, Kumar N, Elamurugan V, Pandian J, Amarakoon S, Berendschot TTJM, Narendran S.   +10 more
europepmc   +1 more source