Results 221 to 230 of about 445,327 (340)

Donor variability alters differentiation and mechanical cohesion of tissue-engineered constructs based on human endothelial / stem cells co-culture [PDF]

open access: gold
Timothée Baudequin   +7 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

The status of donor cancer tissues affects the fate of patient-derived colorectal cancer xenografts in NOG mice

open access: diamond, 2015
Etsuko Fujii   +5 more
openalex   +2 more sources

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

[Repair of skin and soft tissue defects of auricle and donor site with relay flap].

open access: green, 2019
Shusen Chang   +8 more
openalex   +2 more sources

Donor organ cultured corneal tissue selection before penetrating keratoplasty [PDF]

open access: bronze, 1998
Vincent Borderie   +5 more
openalex   +1 more source

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