Results 241 to 250 of about 439,003 (336)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Loss of Insulin-Positive Cell Clusters Precedes the Decrease in Islet Frequency and β-Cell Area in Type 1 Diabetes. [PDF]

Diabetes
Drotar DM, Vazquez Ramos GJA, Williams MD, David ST, Luce C, Smith JA, Posgai AL, Bacher R, Campbell-Thompson M, Kusmartseva I, Brusko MA, Atkinson MA, Wasserfall CH.   +12 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Amygdalar and hippocampal volume loss in limbic-predominant age-related TDP-43 encephalopathy. [PDF]

Brain
Wesseling A, Calandri IL, Bouwman MMA, Reijner N, Deshayes NAC, Barkhof F, Ossenkoppele R, van de Berg WDJ, Rozemuller AJM, Pijnenburg YAL, Hoozemans JJM, Jonkman LE.   +11 more
europepmc   +1 more source

Characterizing Donor-Derived Cells in Nonhematopoietic Tissue

Biology of Blood and Marrow Transplantation, 2006
Ramakrishnan, Aravind, Shi, Daqing, Torok-Storb, Beverly   +2 more
openaire   +2 more sources

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

Regulation of T cell tissue residency and activation in human PCLS. [PDF]

Respir Res
Bargmann T, Sommer C, Stowasser L, Jacob S, Jürgen L, Konzok S, Werlein C, Zardo P, Neubert L, Jonigk D, Fieguth HG, Dahlmann F, Sewald K, Dehmel S, Braun A.   +14 more
europepmc   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Human Peripancreatic Fat Secretome Impacts Local Pancreas Biology. [PDF]

J Clin Endocrinol Metab
Kashyap SR, Alonso LC.
europepmc   +1 more source

Tissue responses to nitric oxide donors: studies in platelets and in myocardium

, 2004
M. Worthley
openalex   +1 more source