Public views on the donation and use of human biological samples in biomedical research: a mixed methods study [PDF]
Objective A mixed methods study exploring the UK general public's willingness to donate human biosamples (HBSs) for biomedical research.<p></p> Setting Cross-sectional focus groups followed by an online survey.<p></p> ...
Clotworthy, M. +6 more
core +1 more source
The intense use of resources to combat COVID-19 causes concern in the entire transplant community because, in addition to physical limitations such as ICU beds, lack of homogeneous treatment protocols and uncertainties about the effects of ...
MARCELO AUGUSTO FONTENELLE RIBEIRO JUNIOR +5 more
doaj +2 more sources
Background A quality assurance programme for the tissue donation process was launched in Andalusia in 2020 to facilitate the integration of tissue donation into end-of-life care, and to respond to the growing need for human tissue for therapeutic ...
Antonia José Alvarez-Marquez +8 more
doaj +1 more source
Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Andréoletti +43 more
core +1 more source
Perceptions and understanding of organ donation among medical undergraduates in Southeastern Nigeria [PDF]
Background/Aim: Organ donation continues to be acknowledged globally as the preferred treatment for individuals with end-stage organ diseases. So far, it is one of the greatest advances of modern science and has resulted in many patients getting a new ...
Njelita Ifeoma Anne +6 more
doaj +1 more source
Donor-derived TB after kidney transplantation: a case report
Introduction: Tuberculosis (TB) is a possible serious complication of solid organ transplantation, associated with high mortality and morbidity. Post-transplant TB has varied pathogenesis with many approaches to its prevention, which is the most ...
Luiz Roberto de Sousa Ulisses +12 more
doaj +2 more sources
Increased expression of 5-hydroxytryptamine(2A/B) receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention [PDF]
Background Idiopathic pulmonary fibrosis (IPF) has a poor prognosis and limited responsiveness to available treatments. It is characterised by epithelial cell injury, fibroblast activation and proliferation and extracellular matrix deposition ...
Amarie, Oana Veronica +8 more
core +1 more source
Francisella tularensis Transmission by Solid Organ Transplantation, 2017
In July 2017, fever and sepsis developed in 3 recipients of solid organs (1 heart and 2 kidneys) from a common donor in the United States; 1 of the kidney recipients died.
Christina A. Nelson +27 more
doaj +1 more source
Optimization of Optical and Mechanical Properties of Real Architecture for 3-Dimensional Tissue Equivalents: Towards Treatment of Limbal Epithelial Stem Cell Deficiency [PDF]
Limbal epithelial stem cell (LESC) deficiency can cause blindness. Transplantation of cultured human limbal epithelial cells (hLE) on human amniotic membrane (HAM) can restore vision but clinical graft manufacture can be unreliable.
Daniels, JT +4 more
core
Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies [PDF]
Rising numbers of patients with cardiovascular diseases and limited availability of donor hearts require new and improved therapy strategies. Human atrial appendage-derived cells (hAACs) are promising candidates for an allogeneic cell-based treatment. In
Diedrichs, Falk +5 more
core +1 more source

