Results 71 to 80 of about 3,873,709 (285)

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

open access: yesAdvanced Science, EarlyView.
Awake longitudinal multimodal ultrasound imaging integrates functional ultrasound (fUS), ultrasound localization microscopy (ULM), and functional ULM (fULM) to characterize cerebrovascular function, microvascular architecture, and flow dynamics within the same animals over time.
Zhe Huang   +9 more
wiley   +1 more source

Comparison of echocardiography with tissue Doppler imaging and magnetic resonance imaging with delayed enhancement in the assessment of children with hypertrophic cardiomyopathy

open access: yes, 2016
Introduction : In children with hypertrophic cardiomyopathy (HCM) there often occurs a non-ischemic pattern of myocardial fibrosis, which could be the cause of impaired left ventricular (LV) diastolic function assessed by tissue Doppler imaging (TDI ...
Lidia Ziółkowska   +3 more
core   +1 more source

A Spatiotemporal Single‐Cell Atlas Uncovers Dysregulated ECM Dynamics and Septal Remodeling Arrest in Human Ventricular Septal Defects

open access: yesAdvanced Science, EarlyView.
Integrating single‐cell and spatial transcriptomics reveals human ventricular septal defect (VSD) as a disease of microenvironmental insufficiency and structural remodeling arrest. Attenuated endothelial‐fibroblast crosstalk, alongside downregulated THBS1/TGF‐β1 and MMP2 signaling networks, impairs the endothelial‐to‐mesenchymal transition (EndoMT) and
Xiaoyuan Zhang   +9 more
wiley   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

open access: yesAdvanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan   +14 more
wiley   +1 more source

Tissue Doppler Imaging: Diagnostic and Prognostic Value

open access: yesJournal of the American College of Cardiology, 2007
The paper by Yu et al. ([1][1]) in the Journal summarized the applications of tissue Doppler imaging (TDI). However, we consider additional clinical applications to be very important. We have used TDI routinely for after-transplant monitoring since 1998.
Dandel, Michael   +3 more
openaire   +2 more sources

Sentinel-1 Imaging Performance Verification with TerraSAR-X [PDF]

open access: yes, 2010
This paper presents dedicated analyses of TerraSAR-X data with respect to the Sentinel-1 TOPS imaging mode. First, the analysis of Doppler centroid behaviour for high azimuth steering angles, as occurs in TOPS imaging, is investigated followed by the ...
Malz, Elke   +7 more
core  

Ischemic Postconditioning Protects Aged Myocardium Against Ischemia/Reperfusion Injury by Regulating Mitochondrial Dynamics via piR‐4913

open access: yesAdvanced Science, EarlyView.
A tiny RNA tips the scales of cardiac injury in aging. piR‐4913 recruits OGT to Drp1 and drives its O‐GlcNAcylation at Thr604, promoting excessive mitochondrial fission that aggravates ischemia‐reperfusion injury. Ischemic postconditioning silences this pathway to restore mitochondrial balance and protect the aged myocardium, revealing piR‐4913 as a ...
Xiangyu Zhao   +11 more
wiley   +1 more source

ALDH2 Deficiency Promotes Mitochondrial Oxidative Stress and Adverse Limb Outcomes via VDAC–HSP60 Signaling

open access: yesAdvanced Science, EarlyView.
ALDH2 deficiency promotes 4‐HNE accumulation, resulting in covalent modification of HSP60, disruption of its oligomeric assembly, and VDAC1‐dependent release of HSP60 from mitochondria to the cytosol. Pharmacological activation of ALDH2 preserves HSP60 proteostasis and mitochondrial integrity, whereas the clinical association between the ALDH2 rs671 ...
You‐Cheng Lin   +7 more
wiley   +1 more source

Is there a role for tissue doppler imaging in infective endocarditis?

open access: yesJournal of Cardiovascular Echography, 2014
An 87-year-old woman was admitted to our Cardiology Department with symptoms and signs of acute congestive heart failure and fever. She had a long history of hypertension and chronic atrial fibrillation. Transthoracic echocardiography showed a large (>10 mm) and mobile mitral valve vegetation, prolapsing into the left ventricular inflow tract, with ...
Sonaglioni, Andrea   +3 more
openaire   +3 more sources

Tissue Doppler imaging data of mitral and tricuspid annulus data obtained by transesophageal echocardiography.

open access: yes, 2014
Va1ues are mean ± SD.W = Wistar; SAD = sinoaortic denervation; SHR = spontaneously hypertensive rats; SHRSAD = spontaneously hypertensive rats with sinoaortic denervation.S’ = peak velocity of systolic velocity obtained by tissue Doppler imaging; E ...
Charles Mady (59479)   +9 more
core   +1 more source

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