Results 141 to 150 of about 614,474 (290)

Collagen matrices from sponge to nano: new perspectives for tissue engineering of skeletal muscle [PDF]

, 2009
Justus P. Beier, Dorothee Klumpp, Markus Rudisile, Roland Dersch, Joachim H. Wendorff, Oliver Bleiziffer, Andreas Arkudas, Elias Polykandriotis, Raymund E. Horch, Ulrich Kneser   +9 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Embroidered Silk Fibroin Scaffolds for ACL Tissue Engineering. [PDF]

Int J Mol Sci
Majeed Y, Gögele C, Elschner C, Werner C, Braun T, Hahn J, Bernhardt R, Krause U, Minnich B, Schulze-Tanzil G.   +9 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Editorial: Advances in biotechnological approaches for reproductive tissue engineering. [PDF]

Front Bioeng Biotechnol
Almeida GHDR, Bressan FF, Miglino MA, Kim MS, Carreira ACO.   +4 more
europepmc   +1 more source

3D-printing-assisted fabrication of chitosan scaffolds from different sources and cross-linkers for dental tissue engineering

, 2021
Mostafa EzEldeen, J.A. Loos, Zohre Mousavi Nejad, Marta Cristaldi, Denise Murgia, Annabel Braem, Reinhilde Jacobs   +6 more
openalex   +1 more source

Tissue Engineering

Molecular Therapy, 2000
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Decellularized rat tubules for tissue engineering. [PDF]

Transl Androl Urol
Jia Q, Li K, Liu T, Kong F, Zhao S, Yang X, Guan Y.   +6 more
europepmc   +1 more source

Preparation and Characterization of porous tubular scaffold made of PCL/PLCL blends for vascular tissue engineering / Azizah Pangesty and Mitsugu Todo [PDF]

, 2017
Azizah Intan Pangesty, Mitsugu Todo
openalex