IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Effect of combined nitrogen on symbiotic nitrogen fixation in pea plants [PDF]
The nitrogen-fixing activity of the symbiotic system of Pisum sativum with Rhizobium leguminosarum is adversely affected by combined nitrogen. Both ammonium chloride and potassium nitrate, when added to the roots, lower the nitrogenase activity ...
Houwaard, F.
core
A Simple Technique for Reconstruction of the Medial Patellofemoral Ligament With Patellar Soft-Tissue Fixation Using Synthetic Suture Tape Internal Bracing. [PDF]
Berger P, Vandenneucker H, Bellemans J.
europepmc +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Endoscopic-Assisted Fibula Reduction With Full Percutaneous Fixation of Ankle Fracture Dislocation
Ankle fracture is one of the most commonly encountered fractures. Open reduction and internal fixation is the gold standard of treatment. However, minimally invasive fixation of ankle fracture is gaining popularity among foot and ankle surgeons as the ...
Chau Ming Hong, M.B.Ch.B., F.H.K.C.O.S., F.H.K.A.M. (Orthopaedic Surgery), F.R.C.S.Ed. (Orth.), M.R.C.S.Ed. +1 more
doaj +1 more source
Revisiting PFA-mediated tissue fixation chemistry: <i>FixEL</i> enables trapping of small molecules in the brain to visualize their distribution changes. [PDF]
Nonaka H +14 more
europepmc +1 more source
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti +5 more
wiley +1 more source
Current Advances in Three-Dimensional Tissue/Organ Printing
Three-dimensional (3D) tissue/organ printing is a major aspect of recent innovation in the field of tissue engineering and regenerative medicine. 3D tissue/organ printing aims to create 3D living tissue/organ analogues, and have evolved along with ...
Jang, J, Park, JH, Cho, DW, Lee, JS
core +1 more source
Survivorship and Reoperation of 324 Consecutive Isolated or Combined Arthroscopic Meniscal Allograft Transplants Using Soft Tissue Fixation. [PDF]
Grassi A +7 more
europepmc +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source

