Results 91 to 100 of about 2,390,613 (305)

The Fixation of Tetanus Toxin by Nervous Tissue [PDF]

Journal of General Microbiology, 1959
SUMMARY: The fixation of tetanus toxin by nervous tissue (Wassermann-Takaki phenomenon, 1898) has been re-investigated. Fixation is greatly dependent on the concentration of toxin and of receptor. Toxin is fixed in preference to toxoid, but its toxicity does not appear to be markedly diminished by fixation.
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

The importance of internal strain as opposed to interface pressure in the prevention of pressure related deep tissue injury

, 2010
For pressure ulcer prevention an ambitious goal would be the establishment of a mechanical threshold for tissue damage. In the past, several researchers have sought to establish such a threshold often involving the loading time.
Oomens, CWJ Cees, Bader, D.L., Loerakker, S Sandra, Loerakker, S., Oomens, C.W.J., Bader, DL Dan, Loerakker, Sandra   +6 more
core   +1 more source

Effect of tissue fixation on the optical properties of structural components assessed by non-linear microscopy imaging. [PDF]

Biomed Opt Express, 2023
Markus MA, Ferrari DP, Alves F, Ramos-Gomes F.   +3 more
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Using E-Z reader to examine the consequences of fixation-location measurement error

, 2015
There is an ongoing debate about whether fixation durations during reading are only influenced by the processing difficulty of the words being fixated (i.e., the serial-attention hypothesis) or whether they are also influenced by the processing ...
Reichle, Erik D., Drieghe, Denis
core   +1 more source

Using a reconstruction locking compression plate as external fixator in infected open clavicle fracture

Orthopedic Reviews, 2013
Open clavicle fracture is an uncommon injury mostly caused by severe direct trauma. It is often associated with multiple organ injuries. Generally, surgical intervention with debridement and fracture repair is always indicated in order to prevent ...
Norachart Sirisreetreerux, Paphon Sa-ngasoongsong, Pongsthorn Chanplakorn, Noratep Kulachote, Sukij Laohajaroensombat, Chanyut Suphachatwong, Vajara Phiphobmongkol, Wiwat Wajanavisit   +7 more
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Histological assessment of PAXgene tissue fixation and stabilization reagents.

PLoS ONE, 2011
Within SPIDIA, an EC FP7 project aimed to improve pre analytic procedures, the PAXgene Tissue System (PAXgene), was designed to improve tissue quality for parallel molecular and morphological analysis.
Marcel Kap, Frank Smedts, Wolter Oosterhuis, Rosa Winther, Nanna Christensen, Bilge Reischauer, Christian Viertler, Daniel Groelz, Karl-Friedrich Becker, Kurt Zatloukal, Rupert Langer, Julia Slotta-Huspenina, Koppany Bodo, Bas de Jong, Uwe Oelmuller, Peter Riegman   +15 more
doaj   +1 more source

Assessing Tissue Fixation Time and Quality with Label-free Mid Infrared Spectroscopy and Machine Learning. [PDF]

Biopreserv Biobank, 2023
Bauer DR, Chafin DR.
europepmc   +1 more source