Results 91 to 100 of about 393,517 (265)

In Vivo Kinematic Analysis of Lateral Meniscal Allograft Transplantation With Soft Tissue Fixation. [PDF]

Orthop J Sports Med, 2021
Macchiarola L, Di Paolo S, Grassi A, Dal Fabbro G, Lucidi GA, Cucurnia I, Zaffagnini S.   +6 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Vital Perfusion-Fixation Technique Through Carotid Arteries for Preparation of Histologic Sections from Periodontium and Jaw Bone of Dog

مجله دانشکده دندانپزشکی اصفهان, 2005
processing of tissues before histologic slices is necessary for preparation of proper histologic sections in animal studies. Fixation is one of the most important and early laboratory stages of tissue processing.
AA - Basiri, M Atabaki, Sh Adibi
doaj  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Timing of open reduction and internal fixation for acute pilon fractures in adults: Early versus delayed — A systematic review and meta-analysis

Journal of Orthopaedic Surgery
Objective To compare the safety, clinical outcomes, and healthcare resource utilization associated with early versus delayed definitive fixation for acute pilon fractures through a systematic review and meta-analysis.
Yang Chen, Huan Liu, Yongzhong Cheng, Haibin Sun, Chaolu Wang, Chaoyue Zhao, Rui Li   +6 more
doaj   +1 more source

Quantitative assessment of fixation strength in combined thread lifting: Comparative analysis of bidirectional-multidirectional versus double bidirectional thread combinations

JPRAS Open
Background: The efficacy of thread lifting procedures for facial rejuvenation is significantly influenced by thread fixation strength and tissue stabilization capabilities. This study presents a quantitative biomechanical comparison between bidirectional
Kyu-Ho Yi, Soo Yeon Park, Jovian Wan, Jong Keun Song, Jin-Hyun Kim, Erik Koppert, Jae Young Kim   +6 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Elevated Pressure Improves the Rate of Formalin Penetration while Preserving Tissue Morphology

Journal of Cancer, 2010
Formaldehyde fixation and paraffin-embedding remains the most widely used technique for processing cancer tissue specimens for pathologic examination, the study of tissue morphology, and archival preservation.
Ingrid E. Chesnick, Jeffrey T. Mason, Timothy J. O'Leary, Carol B. Fowler
doaj