Results 71 to 80 of about 2,390,613 (305)

The Differences of 10% Neutral Buffered Formalin, 4% Paraformaldehyde, and Bouin Solution in Newborn Rat Brain

WMJ (Warmadewa Medical Journal)
Rats are widely used in the study of embryological development of the central nervous system and its congenital disorders. Therefore, tissue fixation is very important in obtaining a good picture of the central nervous system, especially in newborn rats.
Luh Gde Evayanti , Ni Putu Diah Witari , Komang Trisna Sumadewi , A. A. Ayu Asri Prima Dewi , Fransiscus Fiano Anthony Kerans , Dewa Ayu Agung Alit Suka Astini   +5 more
doaj   +1 more source

A Technique of Superficial Medial Collateral Ligament Reconstruction Using an Adjustable-Loop Suspensory Fixation Device

Arthroscopy Techniques, 2015
This report describes superficial medial collateral ligament reconstruction of the knee using a novel method of graft fixation with the ACL Tightrope RT (Arthrex, Naples, FL).
Shaneel Deo, B.H.B.(Hons), M.B.Ch.B., F.R.A.C.S., Alan Getgood, M.Phil., M.D., F.R.C.S.(Tr&Orth), Dip.S.E.M.   +1 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Nitrogen fixation and nitrogenase activity of Azotobacter chroococcum [PDF]

, 1974
The purpose of the present investigation was to study the effect of some chemical, physical and biological factors on growth, efficiency of nitrogen fixation and nitrogenase activity of Azotobacter chroococcum.From biochemical studies with cell-free ...
Brotonegoro, S.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The scale-up of a tissue engineered porous hydroxyapatite polymer composite scaffold for use in bone repair: an ovine femoral condyle defect study

, 2014
The development of an osteogenic bone graft substitute has important practical and cost implications in many branches of medicine where bone regeneration is required.
Oreffo, Richard O. C., Purcell, Matthew, Tayton, Edward, Dunlop, Douglas G., Shakesheff, Kevin M., Goodship, Allen, Fowler, Darren, Smith, James O., Howdle, Steven M., Oreffo, Richard O.C., Blunn, Gordon, Lanham, Stuart, Tayton, Edward R.   +12 more
core   +1 more source

Minimally invasive method for murine brain fixation

BioTechniques, 2005
Complete brain fixation can be achieved with transthoracic cardiac infusion without thoracotomy. Light and electron microscopy tissue sections reveal preservation of cytoplasmic and nuclear structure at all magnification levels.
Kenneth D. Eichenbaum, Joseph W. Eichenbaum, Ahmed Fadiel, Douglas C. Miller, Necdet Demir, Frederick Naftolin, Arnold Stern, Paul H. Pevsner   +7 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Critique of fourier transform infrared microspectroscopy applications to prostate pathology diagnosis [PDF]

, 2010
Prostate cancer is a biologically heterogenous disease with considerable variation in clinical aggressiveness. Gleason grade, the universally accepted method for classification of prostate cancer, is subjective and gives limited predictive information
Aning, Jonathan
core   +3 more sources